Peroxynitrite affects Ca2+ transport in Trypanosoma cruzi

Molecular and Biochemical Parasitology

Volumn 98, Issue 1, 1999, Pages 81-91

  Thomson, Leonor ^a,b   Gadelha, Fernanda R ^c   Peluffo, Gonzalo ^a   Vercesi, Anibal E ^c   Radi, Rafael ^a  

^a DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Ca2+ ATPase activity; Calcium; Calcium transport systems; Peroxynitrite; Trypanosoma cruzi

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIMYCIN; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; OLIGOMYCIN; PEROXYNITRITE; ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATE; CALCIUM; NITRATE; PEROXYNITRIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI; ANIMAL; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; DRUG ANTAGONISM; DRUG EFFECT; ENERGY METABOLISM; HOMEOSTASIS; METABOLISM; MITOCHONDRION; TRANSPORT AT THE CELLULAR LEVEL; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL MEMBRANE PERMEABILITY; ENERGY METABOLISM; HOMEOSTASIS; MEMBRANE POTENTIALS; MITOCHONDRIA; NITRATES; TRYPANOSOMA CRUZI;

EID: 0032588702     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00149-2     Document Type: Article

References (49)

1. Brener Z. Biology of Trypanosoma cruzi. Ann. Rev. Microbiol. 27:1973;347-382.
2. Reed S.G., Nathan C.F., Pihl D.L., Rodricks P., Shanebeck K., Conlon P.J., Grabstein K.H. Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. J. Exp. Med. 166:1987;1734-1746.
3. 2-generating system. Proc. Natl. Acad. Sci. 79:1982;2584-2588.
4. Gazzinelli R.T., Oswald I.P., Hieny S., James S.L., Sher A. The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β Eur. J. Immunol. 22:1992;2501-2506.
5. Petray P., Rottemberg M.E., Grinstein S., Örn A. Release of nitric oxide during the experimental infection with Trypanosoma cruzi. Parasite. Immunol. 16:1994;193-199.
6. Muñoz-Femandez M.A., Fernandez M.A., Fresno M. Synergism between tumor necrosis factor-α and interferon-γ on macrophages activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur. J. Immunol. 22:1992;301-307.
7. Muñoz-Fernandez M.A., Fernandez M.A., Fresno M. Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and INF-γ through a nitric oxide-dependent mechanism. Immunol. Lett. 33:1992;35-40.
8. Ischiropoulos H., Zhu L., Beckman J.S. Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298:1992;446-451.
9. Wang J.F., Komarov P., Sies H., Groot H. Contribution of nitric oxide to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells. Biochem. J. 279:1991;311-314.
10. Denicola A., Rubbo H., Rodriguez D., Radi R. Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi. Arch. Biochem. Biophys. 304:1993;279-286.
11. Koppenol W.H., Pryor W.A., Moreno J.J., Ischiropoulos H., Beckman J.S. Peroxynitrite, a clocked oxidant formed by nitric oxide and superoxide. Chem. Res. Toxicol. 5:1992;834-842.
12. Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite oxidation of sulfhydryls. J. Biol. Chem. 266:1991;4244-4250.
13. Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288:1991;481-487.
14. King P.A., Anderson V.E., Edwards J.O., Gustafson G., Plumb R.C., Suggs J.W. A stable solid that generates hydroxyl radical upon dissolution in aqueous solutions: reaction with proteins and nucleic acids. J. Am. Chem. Soc. 114:1992;5430-5432.
15. Castro L., Rodriguez M., Radi R. Aconitase is readily inactivated by peroxynitrite, but not by its precursor nitric oxide. J. Biol. Chem. 47:1994;29409-29415.
16. Radi R., Rodriguez M., Castro L., Telleri R. Inhibition of the mitochondrial transport chain by peroxynitrite. Arch. Biochem. Biophys. 308:1994;89-95.
17. Packer M.A., Murphy M.P. Peroxynitrite causes calcium efflux from mitochondria which is prevented by cyclosporin A. FEBS. Lett. 345:1994;237-240.
18. Packer M.A., Murphy M.P. Peroxynitrite formed by simultaneous nitric oxide and superoxide generation causes cyclosporin A-sensitive mitochondrial calcium efflux and depolarization. FEBS. Lett. 234:1995;231-239.
19. 2+ release from intact rat liver mitochondria. Biochemistry. 35:1996;4524-4528.
20. 2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation. Arch. Biochem. Biophys. 345:1997;243-250.
21. Rubbo H., Denicola A., Radi R. Peroxynitrite inactivates thiol-containing enzymes of Trypanosoma cruzi energetic metabolism and inhibits cell respiration. Arch. Biochem. Biophys. 308:1994;96-102.
22. Moreno S.N.J., Silva J., Vercesi A.E., Docampo R. Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion. J. Exp. Med. 180:1994;1535-15340.
23. 2+ transport by coupled Trypanosoma cruzi mitochondria in situ. J. Biol. Chem. 264:1989;108-111.
24. 2+ transport by Trypanosoma cruzi mitochondria in situ. Arch. Biochem. Biophys. 272:1989;122-129.
25. Moreno S.N.J., Vercesi A.E., Pignataro O.P., Docampo R. Calcium homeostasis in Trypanosoma cruzi amastigotes: presence of inositol phosphates and lack of an inositol 1,4,5-triphosphate-sensitive calcium pool. Mol. Biochem. Parasitol. 52:1982;251-262.
26. 2+ storage in acidocalcisomes of Trypanosoma cruzi. Biochem. J. 310:1995;1005-1012.
27. Denicola-Seoane A., Rubbo H., Prodanov E., Turrens J. Succinate-dependent metabolism in Trypanosoma cruzi epimastigotes. Molec. Biochem. Parasitol. 54:1992;43-50.
28. Gornall A.G., Bardawill C.J., David M.M. Determination of serum proteins by means of the Biuret reaction. J. Biol. Chem. 177:1949;751-766.
29. Scarpa A Measurement of cation transport with metallochromic indicator. Fleischer S., Packer L. Methods in Enzymology 56. 1979;301-338 Academic Press, New York.
30. Äkerman K.E.O., Wilkstrom M.K.F. Safranine as a probe of the mitochondrial membrane potential. FEBS. Lett. 68:1976;191-197.
31. Vercesi A.E., Bernades C.F., Hoffman M.E., Gadelha F.R., Docampo R. Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ. J. Biol. Chem. 266:1991;14434-14434.
32. Pignataro O.P., Ascoli M. Epidermal growth factor increases the labeling of phosphatidylinositol 3,4-bisphosphate en MA-10 leyding tumor cells. J. Biol. Chem. 265:1990;1718-1723.
33. Docampo R., Pignataro O.P. The inositol phosphate/diacylglycerol signalling pathway in Trypanosoma cruzi. Biochem. J. 275:1991;407-411.
34. Rangel-Aldao R., Allende O., Triana F., Piras R., Henriquez D., Piras M. Possible role of cAMP in the differentiation of Trypanosoma cruzi. Mol. Biochem. Parasitol. 22:1987;39-43.
35. 2+ from the sarcoplasmic reticulum. McCormack J.G., Cobold P.H. Cellular calcium: A practical approach. 1991;313-343 Oxford University Press, New York.
36. 2+ transport in digitonin-permeabilized trypanosomatids. Mol Biochem Parasitol 1990;42:119-124.
37. Philosoph H., Zilberstein D. Regulation of intracellular calcium in promastigotes of the human protozoan parasite Leishmania donovani. J. Biol. Chem. 264:1989;10420-10424.
38. Carafoli E. Intracellular calcium homeostasis. Annul. Rev. Biochem. 56:1987;395-433.
39. + exchange in acidic vacuoles of Trypanosoma brucei. Biochem. J. 304:1994;227-233.
40. 2+ release from acidocalcisomes of Trypanosoma brucei. Biochem. J. 315:1996;265-270.
41. Lehninger AL. Biochemistry. 1981 (Worth Publishers Eds. New York).
42. 2+ transport by plasma membrane vesicles from Trypanosoma cruzi. Biochem. J. 280:1992;715-720.
43. Benaim G., Moreno S.N.J., Hutchinson G., Cervino V., Hermoso T., Romero P.J., Ruiz F., De Souza W., Docampo R. Characterization of the plasma membrane calcium pump from Trypanosoma cruzi. Biochem. J. 306:1995;299-303.
44. Lammel E.M., Barbieri M.A., Wilkowsky S.E., Bertini F., Isola E.L. Trypanosoma cruzi: involvement of intracellular calcium in multiplication and differentiation. Exp. Parasitol. 83:1996;240-249.
45. Carbonera D., Azzone G.F. Permeability of inner mitochondrial membrane and oxidative stress. Biochim. Biophys. Acta. 943:1988;245-255.
46. 2+ plus prooxidants. J. Biol. Chem. 265:1990;19955-19960.
47. 2+ transport ATPase of sarcoplasmic reticulum. Biochem. Biophys. Acta. 1113:1992;323-338.
48. Cannata J.J.B., Cazulo J.J. The aerobic fermentation of glucose by Trypanosoma CNZi. Comp. Biochem. Physiol. 79B:1984;297-308.
49. 2+ homeostasis in Trypanosoma cruzi. Braz. J. Med. Biol. Res. 26:1993;355-363.