-
1
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
M. S. Brown and J. L. Goldstein, A receptor-mediated pathway for cholesterol homeostasis. Science 232, 34-47 (1986).
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
2
-
-
0018181378
-
Low density lipoprotein (LDL) receptor activity in human myelogenous leukemia cells
-
Y. K. Ho, G. S. Smith, M. S. Brown and J. L. Goldstein, Low density lipoprotein (LDL) receptor activity in human myelogenous leukemia cells. Blood 52, 1099-1104 (1978).
-
(1978)
Blood
, vol.52
, pp. 1099-1104
-
-
Ho, Y.K.1
Smith, G.S.2
Brown, M.S.3
Goldstein, J.L.4
-
3
-
-
0019453214
-
Low density lipoprotein as a potential vehicle for chemotherapeutic agents and radionucleotides in the management of gynecologic neoplasms
-
D. Gal, M. Ottashi, P. C. MacDonald, H. J. Buschbaum and E. R. Simpson, Low density lipoprotein as a potential vehicle for chemotherapeutic agents and radionucleotides in the management of gynecologic neoplasms. Am. J. Obstet. Gynecol. 139, 877-885 (1981).
-
(1981)
Am. J. Obstet. Gynecol.
, vol.139
, pp. 877-885
-
-
Gal, D.1
Ottashi, M.2
MacDonald, P.C.3
Buschbaum, H.J.4
Simpson, E.R.5
-
4
-
-
0022384877
-
Hypocholesterolemia in malignancy due to elevated LDL receptor activity in tumor cells: Evidence from studies in leukemic patients
-
S. Vitols, G. Gahrton, M. Bjorkholm and C. O. Peterson, Hypocholesterolemia in malignancy due to elevated LDL receptor activity in tumor cells: Evidence from studies in leukemic patients. Lancet II, 1150-1154 (1985).
-
(1985)
Lancet
, vol.2
, pp. 1150-1154
-
-
Vitols, S.1
Gahrton, G.2
Bjorkholm, M.3
Peterson, C.O.4
-
5
-
-
0022597584
-
Content of low density lipoprotein receptors in breast cancer tissue related to survival of patients
-
M. J. Rudling, L. Stihle, C. O. Peterson and L. Skoog, Content of low density lipoprotein receptors in breast cancer tissue related to survival of patients. Br. Med. J. 292, 580-582 (1986).
-
(1986)
Br. Med. J.
, vol.292
, pp. 580-582
-
-
Rudling, M.J.1
Stihle, L.2
Peterson, C.O.3
Skoog, L.4
-
6
-
-
0025067415
-
Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement
-
M. J. Rudling, B. Angelin, C. O. Peterson and V. P. Collins, Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement. Cancer Res. 50, 483-487 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 483-487
-
-
Rudling, M.J.1
Angelin, B.2
Peterson, C.O.3
Collins, V.P.4
-
7
-
-
0019382396
-
Effect of cell density and confluency on cholesterol metabolism in cancer cells in monolayer culture
-
D. Gal, P. S. MacDonald, J. C. Porter, J. W. Smith and E. R. Simpson, Effect of cell density and confluency on cholesterol metabolism in cancer cells in monolayer culture. Cancer Res. 41, 473-477 (1981).
-
(1981)
Cancer Res.
, vol.41
, pp. 473-477
-
-
Gal, D.1
MacDonald, P.S.2
Porter, J.C.3
Smith, J.W.4
Simpson, E.R.5
-
8
-
-
0021351230
-
Preparation and interaction of a low density lipoprotein:Daunomycin complex with P388 leukemic cells
-
M. Iwanik, K. V. Shaw, B. Ledwith, S. Yanovich and J. M. Shaw, Preparation and interaction of a low density lipoprotein:daunomycin complex with P388 leukemic cells. Cancer Res. 44, 1206-1215 (1984).
-
(1984)
Cancer Res.
, vol.44
, pp. 1206-1215
-
-
Iwanik, M.1
Shaw, K.V.2
Ledwith, B.3
Yanovich, S.4
Shaw, J.M.5
-
9
-
-
0022476847
-
Low density lipoprotein as a carrier of antitumoral drugs: In vivo fate of drug-human low-density lipoprotein complexes in mice
-
M. Masquelier, S. Vitols and C. O. Peterson, Low density lipoprotein as a carrier of antitumoral drugs: In vivo fate of drug-human low-density lipoprotein complexes in mice. Cancer Res. 46, 3842-3847 (1986).
-
(1986)
Cancer Res.
, vol.46
, pp. 3842-3847
-
-
Masquelier, M.1
Vitols, S.2
Peterson, C.O.3
-
10
-
-
0023270613
-
Preparation of drug-low density lipoprotein complexes for delivery of antitumoral drugs via the low density lipoprotein pathway
-
B. Lundberg, Preparation of drug-low density lipoprotein complexes for delivery of antitumoral drugs via the low density lipoprotein pathway. Cancer Res. 47, 4105-4108 (1987).
-
(1987)
Cancer Res.
, vol.47
, pp. 4105-4108
-
-
Lundberg, B.1
-
11
-
-
0025084549
-
Low density lipoprotein for delivery of a water insoluble alkylating agent to malignant cells. In vitro and in vivo studies of drug-lipoprotein complex
-
S. Vitols, K. Soderberg-Reid, M. Masquelier, B. Sjostrom and C. O. Peterson, Low density lipoprotein for delivery of a water insoluble alkylating agent to malignant cells. In vitro and in vivo studies of drug-lipoprotein complex. Br. J. Cancer 62, 724-729 (1990).
-
(1990)
Br. J. Cancer
, vol.62
, pp. 724-729
-
-
Vitols, S.1
Soderberg-Reid, K.2
Masquelier, M.3
Sjostrom, B.4
Peterson, C.O.5
-
12
-
-
0025328321
-
Comparative study of the incorporation of ellipticine-esters into low density lipoprotein (LDL) and selective cell uptake of drug-LDL complex via the LDL receptor pathway in vitro
-
M. Samadi-Baboli, G. Favre, J. Bernadou, D. Berg and G. Soula, Comparative study of the incorporation of ellipticine-esters into low density lipoprotein (LDL) and selective cell uptake of drug-LDL complex via the LDL receptor pathway in vitro. Biochem. Pharmacol. 2, 203-212 (1990).
-
(1990)
Biochem. Pharmacol.
, vol.2
, pp. 203-212
-
-
Samadi-Baboli, M.1
Favre, G.2
Bernadou, J.3
Berg, D.4
Soula, G.5
-
13
-
-
0028386492
-
Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells
-
R. A. Firestone, Low-density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells. Bioconjug. Chem. 5, 105-113 (1994).
-
(1994)
Bioconjug. Chem.
, vol.5
, pp. 105-113
-
-
Firestone, R.A.1
-
14
-
-
0025695510
-
Prolonged serum half-life of antineoplastic drugs by incorporation into the low density lipoprotein
-
P. de Smidt and T. J. C. van Berkel, Prolonged serum half-life of antineoplastic drugs by incorporation into the low density lipoprotein. Cancer Res. 50, 7476-7482 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 7476-7482
-
-
De Smidt, P.1
Van Berkel, T.J.C.2
-
15
-
-
0026467279
-
Elevated uptake of low density lipoproteins by human lung cancer tissue in vivo
-
S. Vitols, C. Peterson, O. Larsson, P. Holm and B. Aberg, Elevated uptake of low density lipoproteins by human lung cancer tissue in vivo. Cancer Res. 52, 6244-6247 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6244-6247
-
-
Vitols, S.1
Peterson, C.2
Larsson, O.3
Holm, P.4
Aberg, B.5
-
16
-
-
0027336379
-
99m-Tc-labeled LDL in B16-melanoma-bearing mice: Visualization of a preferential uptake by the tumor
-
99m-Tc-labeled LDL in B16-melanoma-bearing mice: Visualization of a preferential uptake by the tumor. Int. J. Cancer 54, 411-417 (1993).
-
(1993)
Int. J. Cancer
, vol.54
, pp. 411-417
-
-
Ponty, E.1
Favre, G.2
Benaniba, R.3
Boneu, A.4
Lucot, H.5
Carton, M.6
Soula, G.7
-
17
-
-
0028985072
-
99mTc-low-density lipoprotein in human malignant glioma
-
99mTc-low-density lipoprotein in human malignant glioma. Br. J. Cancer 71, 383-387 (1995).
-
(1995)
Br. J. Cancer
, vol.71
, pp. 383-387
-
-
Leppala, L.1
Kallio, M.2
Nikula, T.3
Nikkinen, P.4
Liewendahl, K.5
Jaaskelainen, J.6
Savolainen, S.7
Gylling, H.8
Hiltunen, J.9
Farkkila, M.10
-
18
-
-
0017864942
-
A new approach for assessing cumulative lysosomal degradation of proteins and other macromolecules
-
R. C. Pittman and D. Steinberg, A new approach for assessing cumulative lysosomal degradation of proteins and other macromolecules. Biochem. Biophys. Res. Commun. 81, 1254-1259 (1978).
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.81
, pp. 1254-1259
-
-
Pittman, R.C.1
Steinberg, D.2
-
19
-
-
0030038709
-
Indium-111 labeling of low density lipoproteins with the DTPA-bis(stearylamide): Evaluation as a potential radiopharmaceutical for tumor localization
-
F. Jasanada, P. Urizzi, J. P. Souchard, F. Le Gaillard, G. Favre and F. Nepveu, Indium-111 labeling of low density lipoproteins with the DTPA-bis(stearylamide): Evaluation as a potential radiopharmaceutical for tumor localization. Bioconjug, Chem. 7, 72-81 (1996).
-
(1996)
Bioconjug, Chem.
, vol.7
, pp. 72-81
-
-
Jasanada, F.1
Urizzi, P.2
Souchard, J.P.3
Gaillard, F.L.4
Favre, G.5
Nepveu, F.6
-
20
-
-
0031038761
-
Internalization of indium-labeled LDL through a lipid chelating anchor in human pancreatic-cancer cells as a potential radiopharmaceutical for tumor localization
-
P. Urizzi, J. P. Souchard, C. Palevody, G. Ratovo, E. Hollande and F. Nepveu, Internalization of indium-labeled LDL through a lipid chelating anchor in human pancreatic-cancer cells as a potential radiopharmaceutical for tumor localization. Int. J. Cancer 70, 315-322 (1997).
-
(1997)
Int. J. Cancer
, vol.70
, pp. 315-322
-
-
Urizzi, P.1
Souchard, J.P.2
Palevody, C.3
Ratovo, G.4
Hollande, E.5
Nepveu, F.6
-
21
-
-
0020563598
-
Biodistribution of a new lipid-soluble CT contrast agent. Evaluation of cholesteryl iopanoate in the rabbit
-
M. A. Longino, J. P. Weichert, S. W. Schwendner, S. M. Szabo, R. E. Counsell and G. M. Glazer, Biodistribution of a new lipid-soluble CT contrast agent. Evaluation of cholesteryl iopanoate in the rabbit. Invest. Radiol. 18, 275-278 (1983).
-
(1983)
Invest. Radiol.
, vol.18
, pp. 275-278
-
-
Longino, M.A.1
Weichert, J.P.2
Schwendner, S.W.3
Szabo, S.M.4
Counsell, R.E.5
Glazer, G.M.6
-
22
-
-
0022970460
-
Potential tumor or organ-imaging agents. 27 polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols
-
J. P. Weichert, M. P. Groziak, M. A. Longino, S. W. Schwendner and R. E. Counsell, Potential tumor or organ-imaging agents. 27 Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols. J. Med. Chem. 29, 2457-2465 (1986).
-
(1986)
J. Med. Chem.
, vol.29
, pp. 2457-2465
-
-
Weichert, J.P.1
Groziak, M.P.2
Longino, M.A.3
Schwendner, S.W.4
Counsell, R.E.5
-
23
-
-
0023948231
-
Iodine-125 cholesteryl iopanoate for measuring extent of atherosclerosis in rabbits
-
M. R. DeGalan, S. W. Schwendner, R. W. S. Skinner, M. A. Longino, M. Gross and R. E. Counsell, Iodine-125 cholesteryl iopanoate for measuring extent of atherosclerosis in rabbits. J. Nucl. Med. 29, 503-508 (1988).
-
(1988)
J. Nucl. Med.
, vol.29
, pp. 503-508
-
-
DeGalan, M.R.1
Schwendner, S.W.2
Skinner, R.W.S.3
Longino, M.A.4
Gross, M.5
Counsell, R.E.6
-
24
-
-
0022556074
-
Sequential flotation ultracentrifugation
-
V. N. Schumaker and D. L. Puppione, Sequential flotation ultracentrifugation. Meth. Enzymol. 128, 155-171 (1986).
-
(1986)
Meth. Enzymol.
, vol.128
, pp. 155-171
-
-
Schumaker, V.N.1
Puppione, D.L.2
-
25
-
-
0005849853
-
Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemic fibroblasts
-
S. K. Basu, J. L. Goldstein, R. G. W Anderson and M. S. Brown, Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemic fibroblasts. Proc. Natl. Acad. Sci. USA 73, 3178-3182 (1976).
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 3178-3182
-
-
Basu, S.K.1
Goldstein, J.L.2
Anderson, R.G.W.3
Brown, M.S.4
-
26
-
-
0031755224
-
Drug targeting using low density lipoprotein (LDL): Physicochemical factors affecting drug loading into LDL particles
-
A. Kader, P. J. Davis, M. Kara and H. Liu, Drug targeting using low density lipoprotein (LDL): physicochemical factors affecting drug loading into LDL particles. J. Controlled Release 55, 231-243 (1998).
-
(1998)
J. Controlled Release
, vol.55
, pp. 231-243
-
-
Kader, A.1
Davis, P.J.2
Kara, M.3
Liu, H.4
-
27
-
-
0016241915
-
Binding and degradation of low density lipoproteins to cultured human fibroblasts
-
J. L. Goldstein and M. S. Brown, Binding and degradation of low density lipoproteins to cultured human fibroblasts. J. Biol. Chem. 249, 5153-5162 (1974).
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 5153-5162
-
-
Goldstein, J.L.1
Brown, M.S.2
-
28
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
-
M. M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72, 248 (1976).
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248
-
-
Bradford, M.M.1
-
29
-
-
0344854156
-
Seal oil markedly enhances the transfer of a hydrophobic radiopharmaceutical into acetylated low density lipoprolein
-
in press
-
W. Xiao, L. Wang, P. J. Davis and H. Liu, Seal oil markedly enhances the transfer of a hydrophobic radiopharmaceutical into acetylated low density lipoprolein. Lipids, in press.
-
Lipids
-
-
Xiao, W.1
Wang, L.2
Davis, P.J.3
Liu, H.4
-
30
-
-
0026696768
-
Low-density lipoprotein for delivery of an acrylophenone antineoplastic molecule into malignant cells
-
S. Lestavel-Delattre, F. Martin-Nizard, V. Clavey, P. Testard, G. Favre, G. Doualin, H. S. Houssaini, J. Bard, P. Duriez and J. Fruchart, Low-density lipoprotein for delivery of an acrylophenone antineoplastic molecule into malignant cells. Cancer Res. 52, 3629-3635 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 3629-3635
-
-
Lestavel-Delattre, S.1
Martin-Nizard, F.2
Clavey, V.3
Testard, P.4
Favre, G.5
Doualin, G.6
Houssaini, H.S.7
Bard, J.8
Duriez, P.9
Fruchart, J.10
-
31
-
-
0009627006
-
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
-
J. L. Goldstein, Y. K. Ho, S. K. Basu and M. S. Brown, Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad Sci. USA 76, 333-337 (1979).
-
(1979)
Proc. Natl. Acad Sci. USA
, vol.76
, pp. 333-337
-
-
Goldstein, J.L.1
Ho, Y.K.2
Basu, S.K.3
Brown, M.S.4
-
32
-
-
0030946330
-
Overview by an oncologist: What are the imaging needs of the oncologist and oncological surgeon?
-
R. Gucalp, J. P. Dutcher and P. H. Wiernik, Overview by an oncologist: What are the imaging needs of the oncologist and oncological surgeon? Semin. Nucl. Med. 27, 3-9 (1997).
-
(1997)
Semin. Nucl. Med.
, vol.27
, pp. 3-9
-
-
Gucalp, R.1
Dutcher, J.P.2
Wiernik, P.H.3
-
33
-
-
0027355226
-
Imaging and dosimetry determinations using radio-labeled antibodies
-
J. Carrasquillo, Imaging and dosimetry determinations using radio-labeled antibodies. Cancer Treat. Res. 68, 65-97 (1993).
-
(1993)
Cancer Treat. Res.
, vol.68
, pp. 65-97
-
-
Carrasquillo, J.1
-
34
-
-
0030579707
-
Doxorubicin in sterically stabilized liposomes
-
D. D. Lasic, Doxorubicin in sterically stabilized liposomes. Nature 380, 561-562 (1996).
-
(1996)
Nature
, vol.380
, pp. 561-562
-
-
Lasic, D.D.1
-
35
-
-
0029951471
-
Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: Pharmacokinetics and biodistribution in tumor bearing mice
-
N. Emmanual, E. Kedar, E. M. Bolotin, N. I. Smorodinsky and Y. Berenholz, Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: Pharmacokinetics and biodistribution in tumor bearing mice. Pharmacol. Res. 13, 861-868 (1996).
-
(1996)
Pharmacol. Res.
, vol.13
, pp. 861-868
-
-
Emmanual, N.1
Kedar, E.2
Bolotin, E.M.3
Smorodinsky, N.I.4
Berenholz, Y.5
-
36
-
-
0028864970
-
Targeted immunoliposomes: Potential role in the delivery of cytotoxic drugs
-
A. Mori and L. Huang, Targeted immunoliposomes: Potential role in the delivery of cytotoxic drugs. Clin. Immunother. 3, 227-240 (1995).
-
(1995)
Clin. Immunother.
, vol.3
, pp. 227-240
-
-
Mori, A.1
Huang, L.2
-
38
-
-
0023630747
-
Delivery of lipophilic drugs using lipoproteins
-
J. M. Shaw, K. V Shaw, S. Yanovich, M. Iwanik, W. S. Futch, A. Rosowsky and L. B. Schook, Delivery of lipophilic drugs using lipoproteins. Ann. NY Acad. Sci. 507, 252-271 (1987).
-
(1987)
Ann. NY Acad. Sci.
, vol.507
, pp. 252-271
-
-
Shaw, J.M.1
Shaw, K.V.2
Yanovich, S.3
Iwanik, M.4
Futch, W.S.5
Rosowsky, A.6
Schook, L.B.7
-
39
-
-
0026606798
-
Treatment of cancer patients with a low density lipoprotein delivery vehicle containing a cytotoxic drug
-
D. Filipowska, T. Filipowski, B. Morelowska, W. Kazanowska, T. Laudanski, S. Lapinjoki, M. Akerland and A. Breeze, Treatment of cancer patients with a low density lipoprotein delivery vehicle containing a cytotoxic drug. Cancer Chemother. Pharmacol. 29, 396-400 (1992).
-
(1992)
Cancer Chemother. Pharmacol.
, vol.29
, pp. 396-400
-
-
Filipowska, D.1
Filipowski, T.2
Morelowska, B.3
Kazanowska, W.4
Laudanski, T.5
Lapinjoki, S.6
Akerland, M.7
Breeze, A.8
-
40
-
-
0032907327
-
Radiolabeled cholesteryl iopanoate/acetylated low density lipoprotein as a potential probe for visualization of early atherosclerotic lesions in rabbits
-
W. Xiao, L. Wang, T. M. Scott, R. E. Counsell and H. Liu, Radiolabeled cholesteryl iopanoate/acetylated low density lipoprotein as a potential probe for visualization of early atherosclerotic lesions in rabbits. Pharmacol. Res. 16, 420-426 (1999).
-
(1999)
Pharmacol. Res.
, vol.16
, pp. 420-426
-
-
Xiao, W.1
Wang, L.2
Scott, T.M.3
Counsell, R.E.4
Liu, H.5
-
41
-
-
0033559933
-
Estimates of the worldwide incidence of 25 major cancers in 1990
-
D. M. Parkin, P. Pisani and J. Ferlay, Estimates of the worldwide incidence of 25 major cancers in 1990. Int. J. Cancer 80, 827-841 (1999).
-
(1999)
Int. J. Cancer
, vol.80
, pp. 827-841
-
-
Parkin, D.M.1
Pisani, P.2
Ferlay, J.3
-
42
-
-
0017239547
-
Receptor-mediated control of cholesterol metabolism
-
M. S. Brown and J. L. Goldstein, Receptor-mediated control of cholesterol metabolism. Science 191, 150-154 (1976).
-
(1976)
Science
, vol.191
, pp. 150-154
-
-
Brown, M.S.1
Goldstein, J.L.2
|