Elevations of serum T3 levels and their association with symptoms in World War II veterans with combat-related posttraumatic stress disorder: Replication of findings in Vietnam combat veterans

Psychosomatic Medicine

Volumn 61, Issue 2, 1999, Pages 131-138

  Wang, Sheila ^a,b   Mason, John ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Combat; Posttraumatic stress disorder; Psychiatric symptoms; Thyroid; Triiodothyronine; World War II veterans

Indexed keywords

CORTICOTROPIN; LIOTHYRONINE; THYROGLOBULIN; THYROTROPIN; THYROXINE; THYROXINE BINDING PROTEIN;

AGED; AROUSAL; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIOTHYRONINE BLOOD LEVEL; MALE; MENTAL DISEASE; NORMAL HUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SOLDIER; SUICIDAL BEHAVIOR; SYMPTOMATOLOGY; THYROID FUNCTION; WAR; BLOOD; CHRONIC DISEASE; HEALTH STATUS; MIDDLE AGED; PSYCHOLOGICAL ASPECT; THYROID FUNCTION TEST; VETERAN; VIET NAM;

CHRONIC DISEASE; COMBAT DISORDERS; HEALTH STATUS; HUMANS; MIDDLE AGED; THYROID FUNCTION TESTS; THYROXINE; THYROXINE-BINDING PROTEINS; TRIIODOTHYRONINE; VETERANS; VIETNAM; WAR;

EID: 0032588166     PISSN: 00333174     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006842-199903000-00001     Document Type: Article

References (31)

1. Mason JW. A review of psychoendocrine research on the pituitary-thyroid system. Psychosom Med 1968;30:666-81.
2. Parry CH. Collections from the unpublished writings of the late CH Parry. London: Underwoods; 1825.
3. Bram I. Psychic trauma and pathogenesis of exophthalmic goiter. Endocrinology 1927;11:106-16.
4. Winsa B, Adami HO, Bergstrom R, Gamstedt A, Dahlberg PA, Adamson U, Jansson R, Karlsson A. Stressful life events and Graves' disease. Lancet 1991;338:1475-9.
5. Harris T, Creed F, Brugha TS. Stressful life events and Graves' disease. Br J Psychiatry 1992;161:535-41.
6. Radosavljevic VR, Jankovic SM, Marindovic JM. Stressful life events in the pathogenesis of Graves' disease. Eur J Endocrinol 1996;134:699-701.
7. Mason J, Southwick S, Yehuda R, Wang S, Riney S, Bremner D, Johnson D, Lubin H, Blake D, Zhou G, Gusman F, Charney D. Elevation of serum-freetriiodothyronine, total triiodothyronine, thyroxine-binding globulin, and total thyroxine levels in combat-related posttraumatic stress disorder. Arch Gen Psychiatry 1994;51:629-41.
8. Mason J, Weizman R, Laor N, Wang S, Schujovitsky A, Abramovitz-Schneider P, Feiler D, Charney D. Serum triiodothyronine elevation in Israeli combat veterans with posttraumatic stress disorder: a cross cultural study. Biol Psychiatry 1996;39:835-8.
9. Mason JW, Kennedy JL, Kosten TR, Giller EL. Serum thyroxine levels in schizophrenic and affective disorder diagnostic sub-groups. J Nerv Ment Dis 1989;177:351-8.
10. Wang S, Mason J, Southwick S, Johnson D, Lubin H Charney D. Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder. Psychosom Med 1995;57:398-402.
11. Wang S, Mason J, Charney D, Yehuda R, Riney S, Southwick S. Relationships between hormonal profile and novelty seeking in combat-related posttraumatic stress disorder. Biol Psychiatry 1997;41:145-51.
12. Keane TM, Caddell JM, Taylor KL. Mississippi Scale for combat-related post-traumatic stress disorder: three studies in reliability and validity. J Consult Clin Psychol 1988;56:85-90.
13. Foa EB, Riggs DS, Dancu CV, Rothbaum BO. Reliability and validity of a brief instrument for assessing posttraumatic stress disorder. J Trauma Stress 1993;6:459-73.
14. Keane TM, Fairbank JA, Caddell JM, Zimering RT, Taylor KL, Mora CA. Clinical evaluation of a measure to assess combat exposure. Psychol Assess J Consult Clin Psychol 1989;1:53-5.
15. Derogotis LR. Brief symptom inventory. Baltimore: Clinical Psychometric Research; 1975.
16. Hesch RD, Gatz J, Pape J, Schmidt E, von zurMuhlen A. Total and free triiodothyronine and thyroid-binding globulin concentration in elderly human persons. Eur J Clin Invest 1976;6: 139-45.
17. Larsen PR, Ingbar SH. The thyroid gland. In: Wilson JD, Foster DW, editors. Williams textbook of endocrinology. 8th ed. Philadelphia: WB Saunders; 1992.
18. Franklyn JA, Ramsden DB, Sheppard MC. The influence of age and sex on tests of thyroid function. Ann Clin Biochem 1985; 22:502-5.
19. Rock R. Interpreting thyroid tests in the elderly. Geriatrics 1995; 40:61-8.
20. Kolb LC, Burris BC, Griffiths S. Propranolol and clonidine in the treatment of chronic post-traumatic stress disorders of war. In: van der Kolk BA, editor. Post-traumatic stress disorder: psychological and biological sequelae. Washington DC: American Psychiatric Press; 1984.
21. Famularo R, Kinscherff R, Fenton T. Propranolol treatment for childhood posttraumatic stress disorder, acute type. A pilot study. Am J Dis Child 1988;142:1244-7.
22. Futterman S, Pumpian-Mindlin E. Traumatic war neuroses five years later. Am J Psychiatry 1951;108:401-8.
23. Brill NQ, Beebe GW. A follow-up study of war neuroses. Washington DC: Veterans Administration; 1955.
24. Archibald HC, Tuddenham RD. Persistent stress reaction after combat. Arch Gen Psychiatry 1965;12:475-81.
25. Keehn RJ, Goldberg ID, Beebe GW. Twenty-four year mortality follow-up of army veterans with disability separations for psychoneurosis in 1944. Psychosom Med 1974;36:27-46.
26. Lee KA, Valliant GE, Torrey WC, Elder GH. A 50-year prospective study of the psychological sequelae of World War II combat. Am J Psychiatry 1995;152:516-22.
27. Elder GH, Shanahan MJ, Clipp EC. Linking combat and physical health: the legacy of World War II in men's lives. Am J Psychiatry 1997;154:330-6.
28. Davidson RT, Kudler HS, Saunders WB, Smith RD. Symptom and comorbidity patterns in World War II and Vietnam veterans with posttraumatic stress disorder. Comp Psychiatry 1990;31: 162-70.
29. Rosenheck R, Fontana A. Long-term sequelae of combat in World War II, Korea, and Vietnam: a comparative study. In: Ursano RJ, McCaughey BG, Fullerton CS, editors. Individual and community responses to trauma and disaster: the structure of human chaos. Cambridge (UK): Cambridge University Press; 1994. p. 331-59.
30. Bauer M, Priebe S, Kurten I, Graf KJ, Baumgartner A. Psychological and endocrine abnormalities in refugees from East Germany, part I: prolonged stress, psychopathology and hypothalamic-pituitary-thyroid axis activity. Psychiatry Res 1994;51: 61-73.
31. Henry JP. Biological basis of the stress response. News Physiol Sci 1993;8:69-73.