Mutual inhibition between Botzinger-complex bulbospinal expiratory neurons detected with cross-correlation in the decerebrate rat

Experimental Brain Research

Volumn 125, Issue 4, 1999, Pages 440-446

  Tian, G F ^a   Peever, J H ^a   Duffin, J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Botzinger complex; Cross correlation; Decerebrate rat; Expiratory neurons; Respiration

Indexed keywords

CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIDROMIC STIMULATION; ARTICLE; DECEREBRATION; INHIBITORY POSTSYNAPTIC POTENTIAL; IONTOPHORESIS; MALE; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY NERVE CELL; SPINAL CORD; SYNAPTIC POTENTIAL; TIME; ANIMAL; BREATHING; CYTOLOGY; ELECTROPHYSIOLOGY; MEDULLA OBLONGATA; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DECEREBRATE STATE; ELECTROPHYSIOLOGY; MALE; MEDULLA OBLONGATA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; SPINAL CORD;

EID: 0032588020     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050701     Document Type: Article

References (28)

1. Anderson KE, Duffin J (1976) An instrument for cross-correlating neurophysiological data in real time. In: National Research Council (eds) Digest of the 11th International Conference on Medical and Biological Engineering. National Research Council, Ottawa, pp 234-235
2. Bianchi AL, Barillot JC (1982) Respiratory neurons in the region of the rectrofacial nucleus: pontile, medullary, spinal and vagal projections. Neurosci Lett 31:277-282
3. Bianchi AL, Grelot L, Iscoe S, Remmers JE (1988) Electrophysiological properties of rostral medullary respiratory neurones in the cat: an intracellular study. J Physiol 407:293-310
4. Bianchi AL, Denavit-Saubié M, Champagnat J (1995) Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev 75:1-45
5. Bryant TH, Yoshida S, De Castro D, Lipski J (1993) Expiratory neurons of the Bötzinger complex of the rat: a morphological study following intracellular labelling with biocytin. J Comp Neurol 335:267-282
6. Duffin J, Alphen J van (1995) Cross-correlation of augmenting expiratory neurons of the Bötzinger complex in the cat. Exp Brain Res 103:251-255
7. Duffin J, Douse MA (1993) Bötzinger expiratory neurones inhibit propriobulbar decrementing inspiratory neurones. Neuroreport 4:1215-1218
8. Duffin J, Ezure K, Lipski J (1995) Breathing rhythm generation: focus on the rostral ventrolateral medulla. News Physiol Sci 10:133-140
9. Ezure K, Manabe M (1988) Decrementing expiratory neurons of the Bötzinger complex. II. Direct inhibitory synaptic linkage with ventral respiratory group neurons. Exp Brain Res 72: 159-166
10. Fedorko L, Duffin J, England SJ (1989) Inhibition of inspiratory neurons of the nucleus retroambigualis by expiratory neurons of the Bötzinger complex in the cat. Exp Neurol 106:74-77
11. Gdovin MJ, Knuth SL, Bartlett D Jr. (1994) Respiratory motor nerve activities during spontaneous bladder contractions. J Appl Physiol 77:1349-1354
12. Graham K, Duffin J (1981) Cross correlation of medullary expiratory neurons in the cat. Exp Neurol 73:451-464
13. Grelot L, Bianchi AL, Iscoe S, Remmers JE (1988) Expiratory neurones of the rostral medulla: anatomical and functional correlates. Neurosci Lett 89:140-145
14. Jiang C, Lipski J (1990) Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat. Exp Brain Res 81:639-648
15. Kalia M, Feldman JL, Cohen MI (1979) Afferent projections to the inspiratory neuronal region of the ventrolateral nucleus of the tractus solitarius in the cat. Brain Res 171:135-141
16. Merrill EG, Fedorko L (1984) Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Bötzinger neurons. J Neurosci 4:2350-2353
17. Merrill EG, Lipski J, Kubin L, Fedorko L (1983) Origin of the expiratory inhibition of nucleus tractus solitarius inspiratory neurones. Brain Res 263:43-50
18. Moore GP, Segundo JP, Perkel DH, Levitan H (1970) Statistical signs of synaptic interaction in neurons. Biophys J 10:876-900
19. Otake K, Sasaki H, Mannen H, Ezure K (1987) Morphology of expiratory neurons of the Bötzinger complex: an HRP study in the cat. J Comp Neurol 258:565-579
20. Sears TA, Stagg D (1976) Short-term synchronization of intercostal motoneurone activity. J Physiol 263:357-381
21. Schwarzacher SW, Wilhelm Z, Anders K, Richter DW (1991) The medullary respiratory network in the rat. J Physiol 435:631-644
22. Tian G-F, Duffin J (1996) Spinal connections of ventral-group bulbospinal inspiratory neurons studied with cross-correlation in the decerebrate rat. Exp Brain Res 111:178-186
23. Tian G-F, Duffin J (1997) Synchronization of ventral-group, bulbospinal inspiratory neurons in the decerebrate rat. Exp Brain Res 117:479-487
24. Tian G-F, Duffin J (1998) Dorsal respiratory group neurons studied with cross-correlation in the decerbrate rat. Exp Brain Res 121:29-34
25. Tian G-F, Peever JH, Duffin J (1998a) Bötzinger-complex expiratory neurons monosynaptically inhibit phrenic motoneurons in the decerebrate rat. Exp Brain Res 122:149-156
26. Tian G-F, Peever JH, Duffin J (1998b) Bötzinger-complex, bulbospinal expiratory neurons monosynaptically inhibit ventral-group respiratory neurons in the decerebrate rat. Exp Brain Res 124:173-180
27. Zheng Y, Barillot JC, Bianchi AL (1991) Patterns of membrane potentials and distributions of the medullary respiratory neurons in the decerebrate rat. Brain Res 546:261-270
28. Zheng Y, Barillot JC, Bianchi AL (1992) Medullary expiratory neurons in the decerebrate rat: an intracellular study. Brain Res 576:245-253