Expansion of γδt cells in an infant with severe combined immunodeficiency syndrome after disseminated BCG infection and bone marrow transplantation

Journal of Allergy and Clinical Immunology

Volumn 103, Issue 6, 1999, Pages 1218-1219

  Fisch, Paul ^a   Millner, Martina ^b   Müller, Susanna M ^c   Wahn, Ulrich ^b   Friedrich, Wilhelm ^c   Renz, Harald ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCOBACTERIAL AGENT; CYCLOSPORIN; ETHAMBUTOL; ISONIAZID; RIFAMPICIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; BCG VACCINATION; BONE MARROW TRANSPLANTATION; CASE REPORT; CELL PROLIFERATION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DISEASE COURSE; FEVER; GRAFT VERSUS HOST REACTION; HEPATOMEGALY; HUMAN; INFANT; INTRAVENOUS DRUG ADMINISTRATION; MALE; MYCOBACTERIOSIS; MYCOBACTERIUM BOVIS; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SKIN BIOPSY; SKIN NODULE; SPLENOMEGALY; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; BLOOD; CHEMISTRY; PATHOLOGY;

BONE MARROW TRANSPLANTATION; HUMANS; INFANT; MALE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM INFECTIONS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTE SUBSETS;

EID: 0032587653     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70205-8     Document Type: Article

References (5)

1. 1. De Libero G. Sentinel function of broadly reactive human γδ T cells. Immunol Today 1997;18:22-6.
2. 2. Abramowsky C, Gonzalez B. Sorensen RU. Disseminated bacillus Calmette-Guérin infections in patients with primary immunodeficiencies. Am J Clin Pathol 1993;100:52-6.
3. 3. Wahn V, Yokota S, Meyer KL, Janssen JW, Hansen-Hagge TE, Knobloch C, et al. Expansion of a maternally derived monoclonal T cell population with CD3+/CD8+ T cell receptor-γδ+ phenotype in a child with severe combined immunodeficiency. J Immunol 1991;147:2934-41.
4. 4. Viale M, Ferrini S, Bacigalupo A. TCR γδ positive lymphocytes after allogeneic bone marrow transplantation. Bone Marrow Transplant 1992;10:249-53.
5. 5. Izzo AA, North RJ. Evidence for an αβ T cell-independent mechanism of resistance to mycobacteria. Bacillus Calmette-Guérin causes progressive infection in severe combined immunodeficient mice, but not in nude mice or in mice depleted of CD4+ and CD8+ T cells. J Exp Med 1992;176:581-6.