[Methyl-11C] thymidine positron emission tomography in tumoral and non-tumoral cerebral lesions

Acta Neurologica Belgica

Volumn 99, Issue 2, 1999, Pages 118-125

  De Reuck, Jacques ^a   Santens, Patrick ^a   Goethals, Patrick ^a   Strijckmans, Karel ^a   Lemahieu, Ignace ^a,b   Boon, Paul ^a   Achten, Eric ^a   Lemmerling, Marc ^a   Vandekerckhove, Tom ^a   Caemaert, Jacques ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Blood brain barrier disruption; Cerebral tumors; Computed tomography; Magnetic resonance imaging; Positron emission tomography

Indexed keywords

CARBON; DIAGNOSTIC AGENT; DRUG DERIVATIVE; METHYLTHYMIDINE; RADIOPHARMACEUTICAL AGENT; THYMIDINE; THYMIDINE C 11; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; ASTROCYTOMA; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN DISEASE; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN TUMOR; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; FEMALE; FOLLOW UP; HEMATOMA; HUMAN; MALE; MIDDLE AGED; PROSPECTIVE STUDY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; TUMOR RECURRENCE; BRAIN BLOOD FLOW; BRAIN INJURY; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; IMAGE ANALYSIS; INTERMETHOD COMPARISON; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY;

ADOLESCENT; ADULT; AGED; ASTROCYTOMA; BLOOD-BRAIN BARRIER; BRAIN DISEASES; BRAIN NEOPLASMS; CARBON RADIOISOTOPES; CEREBRAL CORTEX; CEREBRAL HEMORRHAGE; CEREBRAL INFARCTION; DIAGNOSIS, DIFFERENTIAL; FEMALE; FOLLOW-UP STUDIES; HEMATOMA; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; SENSITIVITY AND SPECIFICITY; SUPRATENTORIAL NEOPLASMS; THYMIDINE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032586916     PISSN: 03009009     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. ALI-AISK M., COLEMAN R. E., LARSON S. M. et al. Advances in clinical imaging using positron emission tomography; National Cancer Institute Workshop Statement. Arch. Intern. Med., 1990, 150 : 735-739.
2. ALAVI J. B., ALAVI A., CHAWLUH J. et al. Positron emission tomography in patients with glioma ; a predictor of prognosis. Cancer, 1988, 62: 1074-1078.
3. BERGSTROM M., ERICSON K., HAGENFELDT L. et al. PET study of methionine accumulation in gliomas and normal brain tissue: competition with branched chain amino acids. J. Comput. Assist. Tomogr., 1987, 11 : 208-213.
4. COLEMAN R. E., HOFFMANN J. M., HANSON M. W. et al. Clinical application of PET for evaluation of brain tumors. J. Nucl. Med., 1991, 32: 616-622.
5. 11C] L-methionine uptake in gliomas. Neurosurgery, 1989, 25 : 720-728.
6. DETHY S., GOLDMAN S., BLECIC S. et al. Carbon-11 methionine and fluorine-18 FDG PET study in brain hematoma. J. Nucl Med., 1994, 35: 1162-1166.
7. 18F] fluorodeoxyglucose in brain tumors : a powerful diagnostic and prognostic tool. Invest. Radiol., 1986, 22 : 360-371.
8. DI CHIRO G. Which PET radiopharmaceutical for brain tumors? J. Nucl. Med., 1991, 32: 1346-1348.
9. FRANCAVILLA T. L., MILETICH R. S., DI CHIRO G. et al. Positron emission tomography in the detection of malignant degeneration of low-grade gliomas. J. Neurosurg., 1989, 25 : 1-5.
10. 11C] thymidine. Appl. Radiat. Isot., 1992, 42 : 952-954.
11. GOETHALS P., VAN EYKEREN M., LODEWIJCK W., DAMS R. Measurement of [methyl-carbon-11] thymidine and its metabolites in head and neck tumours. J. Nucl Med., 1995, 36 : 880-882.
12. 11C] thymidine in Wistar rats. J. Nucl. Med. (in press).
13. HERHOLZ K., PIETRZYK V., VOGES J. et al. Correlation of glucose consumption and tumor cell density in astrocytomas: A stereotactic PET study. J. Neurosurg., 1993, 79 : 853-858.
14. HOLZER T., HERHOLZ K., JESKE J., HEISS W. D. FDG-PET as a prognostic indicator in radiochemotherapy of glioblastoma. J. Comput. Assist. Tomogr., 1993, 17 : 681-687.
15. HOSHINO T. The commentary on the biology and growth kinetics of low-grade and high grade gliomas. J. Neurosurg., 1984, 61 : 895-900.
16. HOSHINO T., NAGASHIMA T., MUROVIC J. A. et al. In situ cell kinetic studies of human neuroectodermal tumours with bromodeoxyuridine labelling. J. Neurosurg., 1986, 64 : 453-459.
17. JANUS T. J., KIM E. E., TILBURY R. et al. Use of [18F] fluoro-deoxyglucose positron emission tomography in patients with primary malignant brain tumors. Ann. Neurol., 1993, 33 : 540-548.
18. 11C] methionine, [3H] thymidine and gallium-67. J. Nucl. Med., 1991, 32: 2118-2123.
19. KUHL D. E., WAGNER H. N., ALAVI A. et al. Positron emission tomography : clinical status in the United States in 1987. J. Nucl. Med., 1988, 29 : 1136-1143.
20. LAMMERTSMA A. A., WISE R. J. S., COX T. C. S. et al. Measurement of blood flow, oxygen utilisation, oxygen extraction ratio and fractional blood volume in human brain tumours and surrounding oedematous tissue. Brit. J. Radiol., 1985, 58 : 725-734.
21. MARTIAL Ph., FERRANT A., LABAR D. et al. In vivo measurement of carbon-11-thymidine uptake in non-Hodgkin's lymphoma using positron emission tomography. J. Nucl. Med., 1988, 29 : 1633-1637.
22. MIGHELI A., ATTANASIO A., MOCELLINI C., SCHIFFER D. Ultrastructural localization of Factor VIII-related antigen in endothelial proliferation of malignant gliomas. Neuropathol. Appl. Neurobiol., 1991, 17 : 11-16.
23. 18F-fluorophenylalanine and positron emission tomography. Surg. Neurol., 1989, 31 : 468-469.
24. MINEURA K., SASAJIMA T., KOWADA M. et al. Innovative approach in the diagnosis of gliomatosis cerebri using carbon-11 L methionine positron emission tomography. J. Nucl. Med., 1991, 32 : 726-728.
25. 11C methionine for diagnosis of recurrent brain tumor and radiation injury. Acta Radiol., 1991, 32 : 197-202.
26. OGAWA T., SHISHIDO F., KANNO I. et al. Cerebral glioma : evaluation with methionine PET. Radiology, 1993, 186 : 45-53.
27. OLIVERO W. C., DULEBOHN S. C., LISTER R. J. The use of PET in evaluating patients with primary tumours: is it useful? J. Neurol. Neurosurg. Psych., 1995, 57 : 250-252.
28. 18F] FDG in brain abscess: a PET study. J. Comput. Assist. Tomogr., 1990, 14 : 486-487.
29. SCHIFFER D., CHIO A., GIORDANA M. T. et al. The vascular response to tumor infiltration in malignant gliomas : Morphometric and reconstruction study. Acta Neuropathol. (Berl.), 1989, 77 : 369-378.
30. SCHIFFER D. Brain tumors: Pathology and its biological correlates. Berlin, Springer-Verlag, 1993 : 148-152.
31. SCHIFTER T., HOFFMAN J. M., HANSON M. W. et al. Serial FDG-PET studies in the prediction of survival in patients with primary brain tumors. J. Comp. Ass. Tomogr., 1993, 17 : 509-516.
32. SEITZ R. J., WECKSLER W. Vascularization of human cerebral gliomas: A lecithin-cytochemical morphometric study. In: Biology of brain tumour. WALKER M. D., THOMAS D. G. T. (eds.), Boston, Martinus Nijhoff, 1986, 132-137.
33. SHIELDS A. F., LARSON S. M., GRUNBAUM Z., GRAHAM M. M. Short-term thymidine uptake in normal and neoplastic tissues : Studies for PET. J. Nucl. Med., 1984, 25 : 759-764.
34. TJUVAJEV J. G., HOMER A., MACAPINLAC A. et al. Imaging of brain tumor proliferative activity with iodine-131-iododeoxyuridine. J. Nucl. Med., 1994, 35 : 1407-1417.
35. TYLER J. L., DIKSIC M., VILLEMURE J. G. et al. Metabolic and hemodynamic evaluation of gliomas using positron emission tomography. J. Nucl. Med., 1987, 28 : 1123-1133.
36. VALK P. E., BUDINGER T. I., LEVIN V. A. et al. PET of malignant cerebral tumors after interstitial brachytherapy: demonstration of metabolic activity and correlation with clinical outcome. J. Neurosurg., 1988, 69 : 830-836.
37. VANDER BORGHT T., PAUWELS S., LAMBOTTE L. et al. Brain tumor imaging with PET and 2-[carbon-11] thymidine. J. Nucl. Med., 1994, 35 : 974-982.
38. 11C-thymidine uptake in tumours of the head and neck using positron emission tomography. Acta Oncol., 1992, 31 : 539-543.
39. 18F] fluorotyrosine. J. Nucl. Med., 1991, 32 : 1338-1346.
40. WONG C. Y. O., YUNG B. C. Y., CONTI P. et al. [C-11] thymidine PET imaging as a measure of DNA synthesis rate: A preliminary quantitative study of human brain glioblastoma. J. Nucl. Med., 1994, 35 : 9P.