P21Wafl/Cipl and p53 expression in the skin-intertwined but not inseparable

British Journal of Dermatology

Volumn 141, Issue 4, 1999, Pages 614-616

  Quinn, A G ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ENZYME INHIBITOR; PROTEIN P53; PROTEIN P21;

DRUG ANTAGONISM; EDITORIAL; HUMAN; METABOLISM; POROKERATOSIS; SKIN; SKIN DISEASE; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; ARTICLE; CELL CYCLE; CLINICAL FEATURE; DISEASE COURSE; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CARCINOMA, SQUAMOUS CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME INHIBITORS; HUMANS; POROKERATOSIS; SKIN; SKIN DISEASES; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032585878     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1999.3097a.x     Document Type: Note

References (12)

1. Schamroth JM, Zlotogorski A, Gilead L,. Porokeratosis of Mibelli. Overview and review of the literature. Acta Derm Venereol 1997; 77: 207 13.
2. Otsuka F, Someya T, Ishibashi Y,. Porokeratosis and malignant skin tumors [editorial]. J Cancer Res Clin Oncol 1991; 117: 55 60.
3. Otsuka F, Shima A, Ishibashi Y,. Porokeratosis has neoplastic clones in the epidermis: microfluorometric analysis of DNA content of epidermal cell nuclei. J Invest Dermatol 1989; 92: 231S 3S.
4. Gray MH, Smoller BS, McNutt NS,. Carcinogenesis in porokeratosis. Evidence for a role relating to chronic growth activation of keratinocytes. Am J Dermatopathol 1991; 13: 438 44.
5. Ponten F, Berne B, Ren ZP, Nister M, Ponten J,. Ultraviolet light induces expression of p53 and p21 in human skin: effect of sunscreen and constitutive p21 expression in skin appendages. J Invest Dermatol 1995; 105: 402 6.
6. Liu M, &, Pelling JC,. UV-B/A irradiation of mouse keratinocytes results in p53-mediated WAF1/CIP1 expression. Oncogene 1995; 10: 1955 60.
7. Campbell C, Quinn AG, Angus B, Rees JL,. The relation between p53 mutation and p53 immunostaining in non-melanoma skin cancer. Br J Dermatol 1993; 129: 235-41.
8. Rehman 1 Takata M, Wu YY, Rees JL,. Genetic change in actinic keratoses. Oncogene 1996; 12: 2483 90.
9. Matsuta M, Kon S, Sasaki K, Matsuta M,. Immunohistochemical detection of p21WAF1/CIP1 and p53 proteins in formalin-fixed paraffin-embedded tissue sections of squamous cell carcinoma of the skin. J Dermatol Sci 1997; 14: 233 9.
10. Magee JW, McCalmont TH, LeBoit PE,. Overexpression of p53 tumor suppressor protein in porokeratosis. Arch Dermatol 1994; 130: 187 90.
11. Urano Y, Sasaki S, Ninorniya Y, Oura H, Arase S,. Immunohistochemical detection of p53 tumor suppressor protein in porokeratosis. J Dermatol 1996; 23: 365 8.
12. Ninomiya Y, Urano Y, Yoshimoto K, et al,. p53 gene mutation analysis in porokeratosis and porokeratosis-associated squamous cell carcinoma. J Dermatol Sci 1997; 14: 3 8.