Conformational preference of two toad poison bufadienolides, bufarenogin and Ψ-bufarenogin

Heterocycles

Volumn 49, Issue 1, 1998, Pages 275-279

  Kamano, Yoshiaki ^a   Kotake, Ayano ^a   Takano, Rui ^a   Morita, Hiroshi ^b   Takeya, Koichi ^b   Itokawa, Hideji ^b  

^a KANAGAWA UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUFADIENOLIDE DERIVATIVE; BUFARENOGIN; PSI BUFARENOGIN; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATION; MOLECULAR DYNAMICS; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; TOAD; TOXIN ANALYSIS;

EID: 0032585392     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-98-S28     Document Type: Article

References (11)

1. a) T. Nanba, "Genshoku Wakanyaku Zukan"(Π), Hoikusha, 1980,.246-269.
2. b) T. Suga, "Taisha"(Zokango), 1973, 10, 762.
3. S. Yoshida, Y. Kamano, and T. Sakai, Chem. Pharm. Bull. 1976, 24, 1714.
4. Y. Jing, H. Ohizumi, N. Kawazoe, S. Hashimoto, Y. Masuda, S. Nakajo, T. Yoshida, Y. Kuroiwa, and K. Nakaya, Jpn. J. Cancer Res., 1994, 85, 645.
5. Y. Kamano, A. Kotake, H. Hashima, M. Inoue, H. Morita, K. Takeya, H. Itokawa, N. Nandachi, T. Segawa, A. Yukita, K. Saitou, M. Katsuyama, and G. R. Pettit, Bioorg. Med. Chem., in press.
6. K. Huber, H. Linde, and K. Meyer, Helv. Chim. Acta, 1967, 50, 1994.
7. D. D. Mcintryre, M. W. Germann, and H. J. Vogel, Can. J. Chem., 1990, 68, 1263.
8. H. Morita, K. Kondo, Y. Hitotsuyanagi, K. Takeya, H. Itokawa, N. Tomioka, A. Itai, and Y. litaka, Tetrahedron, 1991, 47, 2757.
9. J. J. P. Stewart, J. Computational Chem., 1989, 10, 221.
10. Molecular-modeling software SYBYL ver. 6.3 (Tripos, Inc., St. Louis, MO)
11. M. Clark, R. D. Cramer III, and N. V. Opdenbosch, J. Comp. Chem., 1989, 10, 982.