Structural and functional characterization of Streptomyces plicatus β- N-acetylhexosaminidase by comparative molecular modeling and site-directed mutagenesis

Journal of Biological Chemistry

Volumn 273, Issue 31, 1998, Pages 19618-19624

  Mark, Brian L ^a   Wasney, Gregory A ^a   Salo, Tim J S ^a   Khan, Amir R ^b   Cao, Zhimin ^a,d   Robbins, Phillips W ^c   James, Michael N G ^b   Triggs Raine, Barbara L ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVITY; GANGLIOSIDOSIS; GENE EXPRESSION; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SERRATIA MARCESCENS; SITE DIRECTED MUTAGENESIS; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BETA-N-ACETYLHEXOSAMINIDASE; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STREPTOMYCES;

SERRATIA MARCESCENS; SPHEX; STREPTOMYCES; STREPTOMYCES PLICATUS;

EID: 0032584586     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.31.19618     Document Type: Article

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