Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells

Experimental and Molecular Medicine

Volumn 30, Issue 1, 1998, Pages 47-51

  Sohn, Jeongwon ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Cell cycle; Interleukin 4; Panax ginseng; Panaxydol; Panaxynol; Renal cell carcinoma

Indexed keywords

DNA; INTERLEUKIN 4; PANAXYDOL; PANAXYNOL; PETROLEUM DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; FLOW CYTOMETRY; GINSENG; HUMAN; HUMAN CELL; KIDNEY CARCINOMA;

PANAX GINSENG;

EID: 0032584128     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.1998.7     Document Type: Article

References (11)

1. Brekman, I.I. and Dardymov, I. V. (1969) New substances of plant origin which increase nonspecific resistance. Annu. Rev. Pharmacol. 9: 419-430
2. Cheon, J., Chung, D. J., Kim, J. J., Koh, S. K. and Sohn, J. (1996) Inhibitory effects of interleukin 4 on human renal cell carcinoma cells in vitro in combination with interferon-alpha, tumor necrosis factor-alpha, or interleukin 2. Int. J. Urol. 3: 196-201
3. Hoon, D. B. S., Okun, E., Banez, M., Irie, R. F. and Morton, D. L (1991) lnterleukin-4 alone and with Interferon or tumor necrosis factor inhibits cell growth and modulates cell surface antigen on human renal cell carcinomas. Cancer Res. 51: 5687-5693
4. Hwang, W. I. and Cha, S. M. (1978) A cytotoxic activity of extract of Panax ginseng root against some cancer cells in vitro and in vivo. Proc. 2nd Int. Ginseng Symp. 43-49
5. Hwang, W. I. (1993) A study on the antitumor activity of Panax ginseng. Korean J. Ginseng Sci. 17: 52-601
6. Kim, S. R, Cho, C. K., Yoo, S. Y, Koh, K. H., Yun, H. G. and Kim, T. H. (1993) In vivo radioprotective activity of Panax ginseng and diethyldithio-carbamate. In Vivo 7. 467-470
7. Kimura, I, Saunders, P. A., Kim, H. S., Rheu, H. M., Oh, K. W. and Ho, I. K. (1994) Interactions of ginsenosides with ligand bindings of GABA (A) and GABA(B) receptors. Gen. Pharmacol. 25: 193-199
8. Lee, S. H. and Hwang, W. I. (1986) Inhibitory effect of petroleum ether extract of Panax ginseng root against growth of human cancer cells. J. Ginseng. Sci. 10: 141-150
9. Matsunaga, H., Katano, M., Yamamoto, H., Fujito, H., Mori, M. and Takata, K. (1990) Cytotoxic activity of polyacetylenic compounds in Panax ginseng C. A. Meyer. Chem. Pharm. Bull. 38: 3480-3482
10. 2+ channels through a pertussis toxin sensitive G protein. Proc. Natl. Acad. Sci.USA 92: 8739-8743
11. Stancheva, S. L. and Alova, L. G. (1993) Ginsenoside Rg1 inhibits the brain cAMP phosphodiesterase activity in young and aged rats. Gen. Pharmacol. 24: 1459-1462