Effect of cocaine, 95% oxygen and ellagic acid on the development and antioxidant status of cultured rat embryos

Toxicology Letters

Volumn 95, Issue 1, 1998, Pages 15-21

  Bohn, A A ^a   Forsyth, C S ^b   Stoner, G D ^c   Reed, D J ^d   Frank, A A ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d OREGON STATE UNIVERSITY   (United States)

Author keywords

Antioxidant status; Cocaine; Cultured rat embryos; Ellagic acid; Oxygen

Indexed keywords

ANTIOXIDANT; COCAINE; ELLAGIC ACID; GLUTATHIONE; OXYGEN;

ARTICLE; CROWN RUMP LENGTH; EMBRYO; EMBRYO DEVELOPMENT; LIPID PEROXIDATION; NONHUMAN; PERINATAL DEATH; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; UTERUS BLOOD FLOW;

EID: 0032584003     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0378-4274(98)00010-1     Document Type: Article

References (33)

1. Barch, D.H., Rundhaugen, L.M., Sokalingum Pillay, N., 1995. Ellagic acid induces transcription of the rat glutathione S-transferase-Ya gene. Carcinogenesis 16, 665-668.
2. Barton, S.J., Harrigan, R., Tse, A.M., 1995. Prenatal cocaine exposure: implications for practice, policy development, and needs for future research. J. Perinatol. 15, 10-22.
3. Brent, R.L., 1990. Relationship between uterine vascular clamping, vascular disruption syndrome, and cocaine teratogenicity. Teratology 41, 757-760.
4. Brown, N.A., Fabro, S., 1981. Quantitation of rat embryonic development in vitro: a morphological scoring system. Teratology 24, 65-78.
5. Burin, G.J., Al-Ghaith, L.K., Anitole, K.G., Barber, M.K., Brown, K.M., 1991. Investigation of the developmental toxicity of cocaine in in vitro cultured chick embryos: correlation of effects with intra-embryonic drug levels. Toxicol. in vitro 5, 285-293.
6. Chasnoff, I.J., 1992. Cocaine, pregnancy and the growing child. Curr. Prob. Pediatr. 22, 302-322.
7. Church, M.W., Dintcheff, B.A., Gessner, P.K., 1988. Dose-dependent consequences of cocaine on pregnancy outcome in the Long-Evans rat. Neurotoxicol. Teratol. 10, 51-58.
8. 2. J. Appl. Physiol. 30, 753-763.
9. Ellis, J.E., Byrd, L.D., Sexson, W.R., Patterson-Barnett, C.A., 1993. In utero exposure to cocaine: a review. Southern Med. J. 86, 725-731.
10. Fantel, A.G., Person, R.E., Burroughs-Gleim, C.J., Mackler, B., 1990. Direct embryotoxicity of cocaine in rats: effects on mitochondrial activity, cardiac function, and growth and development in vitro. Teratology 42, 35-44.
11. Fantel, A.G., Barber, C.V., Mackler, B, 1992a. Ischemia-reperfusion: a new hypothesis for the developmental toxicity of cocaine. Teratology 46, 285-292.
12. Fantel, A.G., Barber, C.V., Carda, M.B., Tumbic, R.W., Mackler, B., 1992b. Studies of the role of ischemia-reperfusion and superoxide anion radical production in the teratogenicity of cocaine. Teratology 46, 293-300.
13. Fariss, M.W., Reed, D.J., 1987. High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives. Meth. Enzymol. 143, 101-109.
14. Finnell, R.H., Toloyan, S., Van Waes, M., Kalivas, P.W., 1990. Preliminary evidence for a cocaine-induced embryopathy in mice. Toxicol. Appl. Pharmacol. 103, 228-237.
15. Fisher, J.E., Potturi, R.B., Collins, M., Resnick, E., Zimmerman, E.F., 1994. Cocaine-induced embryonic cardiovascular disruption in mice. Teratology 49, 182-191.
16. Frank, A.A., Collier, J.M., Forsyth, C.S., Heur, Y.-H., Stoner, G.D., 1992. Ellagic acid protects rat embryos in culture from the embryotoxic effects of N-methyl-N-nitrosourea. Teratology 46, 109-115.
17. Frank, D.A., Bresnahan, K., Zuckerman, B.S., 1993. Maternal cocaine use: impact on child health and development. Adv. Pediatr. 40, 65-99.
18. Gonzalez, N.M., Campbell, M., 1994. Cocaine babies: does prenatal exposure to cocaine affect development? J. Am. Acad. Child Adolesc. Psychiatry 33, 16-19.
19. Holzman, C., Paneth, N., 1994. Maternal cocaine use during pregnancy and perinatal outcomes. Epidemiol. Rev. 16, 315-334.
20. Kain, Z.N., Kain, T.S., Scarpelli, E.M., 1992. Cocaine exposure in utero: perinatal development and neonatal manifestations - review. Clin. Toxicol. 30, 607-636.
21. Kapur, R.P., Shaw, C.M., Shepard, T.H., 1991. Brain hemorrhages in cocaine exposed human fetuses. Teratology 44, 11-18.
22. Mahalik, M.P., Gautieri, R.F., Mann, D.E., 1980. Teratogenic potential of cocaine hydrochloride in CF-1 mice. J. Pharm. Sci. 69, 703-706.
23. Moore, T.R., Sorg, J., Miller, L., Key, T.C., Resnick, R., 1986. Hemodynamic effects of intraveneous cocaine on the pregnant ewe and fetus. Am. J. Obstet. Gynecol. 155, 883-888.
24. New, D.A.T., 1978. Whole-embryo culture and the study of mammalian embryos during organogenesis. Biol. Rev. 53, 81-122.
25. Plessinger, M.A., Woods, J.R., 1993. Maternal, placental, and fetal pathophysiology of cocaine exposure during pregnancy. Clin. Obstet. Gynecol. 36, 267-278.
26. Richardson, G.A., Day, N.L., McGauhey, P.J., 1993. The impact of prenatal marijuana and cocaine use on the infant and child. Clin. Obstet. Gynecol. 36, 302-318.
27. Shoji, R., Kimura, R., Matsuda, M., Matsui, F., Naruse, I., Oohira, A., 1989. Developmental toxicity assessment of DMSO with whole embryo culture and tissue reconstruction systems. Teratology 40, 661.
28. Slutsker, L., 1992. Risks associated with cocaine use during pregnancy. Obstet. Gynecol. 79, 778-789.
29. Webster, W.S., Brown-Woodman, P.D.C., 1990. Cocaine as a cause of congenital malformations of vascular origin: experimental evidence in the rat. Teratology 41, 689-697.
30. Woods, J.R., Plessinger, M.A., Clark, K.E., 1987. Effect of cocaine on uterine blood flow and fetal oxygenation. J. Am. Med. Assoc. 257, 957-961.
31. Woods, J.R., Plessinger, M.A., Scott, K., Miller, R.K., 1989. Prenatal cocaine exposure to the fetus: a sheep model for cardiovascular evaluation. Ann. NY Acad. Sci. 252, 267-279.
32. Young, S.L., Vosper, H.J., Phillips, S.A., 1992. Cocaine: its effects on maternal and child health. Pharmacotherapy 12, 2-17.
33. Zimmerman, E.F., Potturi, R.B., Resnick, E., Fisher, J.E., 1994. Role of oxygen free radicals in cocaine-induced vascular disruption in mice. Teratology 49, 192-201.