Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes

Toxicology Letters

Volumn 94, Issue 2, 1998, Pages 115-125

  Amacher, David E ^a   Schomaker, Shelli J ^a  

^a PFIZER INC   (United States)

Author keywords

CYP3A; Cytochrome P450; Ethylmorphine N demethylase; Liver; Rat

Indexed keywords

16ALPHA CYANOPREGNENOLONE; BETA NAPHTHOFLAVONE; CLOFIBRATE; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; ENZYME INDUCING AGENT; ETHYLMORPHINE N DEMETHYLASE; ISONIAZID; PHENOBARBITAL; POLYCLONAL ANTIBODY; TROLEANDOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ANIMALS; ANTIBODIES; ARYL HYDROCARBON HYDROXYLASES; BETA-NAPHTHOFLAVONE; BIOLOGICAL MARKERS; CLOFIBRATE; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; ENZYME INDUCTION; ENZYME INHIBITORS; ETHYLMORPHINE-N-DEMETHYLASE; FEMALE; ISONIAZID; MALE; MICROSOMES, LIVER; OXIDOREDUCTASES, N-DEMETHYLATING; PHENOBARBITAL; PREGNENOLONE CARBONITRILE; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; SEX FACTORS;

ANIMALIA;

EID: 0032583895     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)00108-2     Document Type: Article

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