Insular cortex lesions alter baroreceptor sensitivity in the urethane- anesthetized rat

Brain Research

Volumn 813, Issue 1, 1998, Pages 73-81

  Zhang, Z H ^a   Rashba, S ^a   Oppenheimer, S M ^a  

^a NONE

Author keywords

Blood pressure; Forebrain; Heart rate; Insular lateralization

Indexed keywords

HYPERTENSIVE AGENT; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; URETHAN;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRAIN INJURY; CARDIOVASCULAR RESPONSE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; HEART RATE; INSULA; MALE; NONHUMAN; PRESSORECEPTOR; PRIORITY JOURNAL; RAT; SYMPATHETIC TONE;

ANESTHETICS, INTRAVENOUS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIOTONIC AGENTS; CEREBRAL CORTEX; HEART RATE; MALE; NITROPRUSSIDE; PHENYLEPHRINE; PRESSORECEPTORS; RATS; RATS, SPRAGUE-DAWLEY; URETHANE;

EID: 0032583263     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00996-2     Document Type: Article

References (18)

1. Butcher K., Cechetto D. Autonomic responses of the insular cortex in hypertensive and normotensive rats. Am. J. Physiol. 37:1995;214-222.
2. Butcher K., Cechetto D. Insular lesion evokes autonomic effects of stroke in normotensive and hypertensive rats. Stroke. 26:1995;459-465.
3. Cechetto D., Saper C. Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat. J. Comp. Neurol. 262:1987;27-45.
4. Cheung R.T., Hachinski V.C., Cechetto D. Cardiovascular response to stress after middle cerebral artery occlusion in rats. Brain Research. 747(2):1997;181-188.
5. Coleman T.G. Arterial baroreflex control of heart rate in the conscious rat. Am. J. Physiol. 238:1980;515-520.
6. Hachinski V.C., Oppenheimer S.M., Wilson J.X., Guiraudon C., Cechetto D. Asymmetry of sympathetic consequences of experimental stroke. Arch. Neurol. 49:1992;697-702.
7. Kulshreshtha N., Zhang Z.H., Oppenheimer S.M. Effects of insular lesions on the rat baroreceptor reflex. Soc. Neurosci. Abstr. 22(i):1996;389.
8. Oppenheimer S., Cechetto D. Cardiac chronotropic organisation of the rat insular cortex. Brain Research. 533:1990;66-72.
9. Oppenheimer S.M., Gelb A.W., Girvin J.P., Hachinski V.C. Cardiovascular effects of human insular stimulation. Neurology. 42:1992;1727-1732.
10. S.M. Oppenheimer, D.A. Hopkins, Suprabulbar regulation of cardiac rate and rhythm, in: J.A. Armour, J.L. Ardell (Eds.), Neurocardiology, Oxford Univ. Press, New York, 1994.
11. Oppenheimer S.M., Martin W.M., Kedem G. Left insular cortex lesions perturb cardiac autonomic tone. Clinical Autonomic Research. 6:1996;131-140.
12. Oppenheimer S.M., Zhang Z.H., Dougherty P.M. Convergence of baroreceptive and nociceptive neurons in the monkey insular cortex. Soc. Neurosci. Abstr. 23:1997;423.
13. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, New York, 1986.
14. Saad M., Huerta F., Trancard J., Elghozi J. Effects of middle cerebral artery occlusion on baroreceptor reflex control of heart rate in the rat. J. Auton. Nerv. Syst. 27:1989;165-172.
15. Yasui Y., Breder D., Saper C., Cechetto D. Autonomic responses and efferent pathways form the insular cortex in the rat. J. Comp. Neurol. 303:1991;355-374.
16. Zamrini F.E., Meador K., Loring D.et al. Unilateral cerebral inactivation produces differential left/right heart rate responses. Neurology. 40:1990;1408-1411.
17. Zhang Z., Oppenheimer S.M. Characterization, distribution and lateralization of baroreceptor related neurons in the rat insular cortex. Brain Research. 760:1997;243-250.
18. Zhang Z., Oppenheimer S.M. Characterization of baroreceptor related units in the monkey insular cortex. Brain Research. 796:1998;303-306.