메뉴 건너뛰기




Volumn 813, Issue 1, 1998, Pages 67-72

Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: In vivo microdialysis study in conscious animals

Author keywords

Dopamine; Fenfluramine; Phentermine; Serotonin; Striatum

Indexed keywords

DOPAMINE; FENFLURAMINE; PHENTERMINE; SEROTONIN;

EID: 0032583262     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01003-8     Document Type: Article
Times cited : (34)

References (36)
  • 1
    • 0031908645 scopus 로고    scopus 로고
    • Effects of phentermine on striatal dopamine and serotonin release in conscious rats: In vivo microdialysis study
    • Balcioglu A., Wurtman R.J. Effects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study. Int. J. Obes. 22:1998;325-328.
    • (1998) Int. J. Obes. , vol.22 , pp. 325-328
    • Balcioglu, A.1    Wurtman, R.J.2
  • 2
    • 0031951628 scopus 로고    scopus 로고
    • Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism
    • Balcioglu A., Wurtman R.J. Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism. J. Pharm. Exp. Ther. 283:1998;991-997.
    • (1998) J. Pharm. Exp. Ther. , vol.283 , pp. 991-997
    • Balcioglu, A.1    Wurtman, R.J.2
  • 3
    • 0031892111 scopus 로고    scopus 로고
    • Combined phentermine/fenfluramine administration and central serotonin neurons
    • Bauman M.H., Rothman R.B. Combined phentermine/fenfluramine administration and central serotonin neurons. Synapse. 28:1998;339-942.
    • (1998) Synapse , vol.28 , pp. 339-942
    • Bauman, M.H.1    Rothman, R.B.2
  • 4
    • 0017127060 scopus 로고
    • The microsomal N-oxidation of phentermine
    • Beckett A.H., Belanger P.M. The microsomal N-oxidation of phentermine. J. Pharm. Pharmacol. 28:1976;692-699.
    • (1976) J. Pharm. Pharmacol. , vol.28 , pp. 692-699
    • Beckett, A.H.1    Belanger, P.M.2
  • 5
    • 0025864504 scopus 로고
    • Facilitation of dopamine release in vivo by serotonin agonists: Studies with microdialysis
    • Benloucif S., Galloway M.P. Facilitation of dopamine release in vivo by serotonin agonists: studies with microdialysis. Eur. J. Pharmacol. 200:1991;1-8.
    • (1991) Eur. J. Pharmacol. , vol.200 , pp. 1-8
    • Benloucif, S.1    Galloway, M.P.2
  • 6
    • 0027493103 scopus 로고
    • Serotonin-facilitated dopamine release in vivo. Pharmacological characterization
    • Benloucif S., Keegan M.J., Gallaway M.P. Serotonin-facilitated dopamine release in vivo. Pharmacological characterization. J. Pharmacol. Exp. Ther. 265:1993;373-377.
    • (1993) J. Pharmacol. Exp. Ther. , vol.265 , pp. 373-377
    • Benloucif, S.1    Keegan, M.J.2    Gallaway, M.P.3
  • 7
    • 0023406490 scopus 로고
    • Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fibre through the dorsal hippocampus in the rat
    • Benveniste H., Drejer J., Shousbrou A., Diemer N.H. Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fibre through the dorsal hippocampus in the rat. J. Neurochem. 49:1987;729-734.
    • (1987) J. Neurochem. , vol.49 , pp. 729-734
    • Benveniste, H.1    Drejer, J.2    Shousbrou, A.3    Diemer, N.H.4
  • 8
    • 0023198998 scopus 로고
    • Neuroleptic-like effects of the L-isomer of fenfluramine on striatal dopamine release in freely moving rats
    • Bettini E., Ceci A., Spinelli R., Samanin R. Neuroleptic-like effects of the L-isomer of fenfluramine on striatal dopamine release in freely moving rats. Biochem. Pharmacol. 36:1987;2387-2391.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 2387-2391
    • Bettini, E.1    Ceci, A.2    Spinelli, R.3    Samanin, R.4
  • 9
    • 0028986136 scopus 로고
    • Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: A microdialysis study in the halothane-anesthetized rat
    • Bonhomme N., De Deurwaerdere N.P., Le Moal M., Spampinato U. Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat. Neuropharmacology. 34:1995;269-279.
    • (1995) Neuropharmacology , vol.34 , pp. 269-279
    • Bonhomme, N.1    De Deurwaerdere, N.P.2    Le Moal, M.3    Spampinato, U.4
  • 10
    • 0025924932 scopus 로고
    • Activation of 5-HT3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens
    • Chen J., van Praag H.M., Gardner E.L. Activation of 5-HT3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens. Brain Res. 543:1991;354-357.
    • (1991) Brain Res. , vol.543 , pp. 354-357
    • Chen, J.1    Van Praag, H.M.2    Gardner, E.L.3
  • 11
    • 0018574827 scopus 로고
    • The effect of propranolol, phentolamine and pimozide on drug-induced anorexia in the mouse
    • Dobrzanski S., Doggett N.S. The effect of propranolol, phentolamine and pimozide on drug-induced anorexia in the mouse. Psychopharmacology. 66:1979;297-300.
    • (1979) Psychopharmacology , vol.66 , pp. 297-300
    • Dobrzanski, S.1    Doggett, N.S.2
  • 12
    • 0027337279 scopus 로고
    • Dopamine D2 receptor-mediated regulation of serotonin extracellular concentration in the dorsal raphe nucleus of freely moving rats
    • Ferre S., Artigas F. Dopamine D2 receptor-mediated regulation of serotonin extracellular concentration in the dorsal raphe nucleus of freely moving rats. J. Neurochem. 61:1993;772-775.
    • (1993) J. Neurochem. , vol.61 , pp. 772-775
    • Ferre, S.1    Artigas, F.2
  • 13
    • 0027318008 scopus 로고
    • Local infusion of the selective 5-HT1b agonist CP-93,129 facilitates striatal dopamine release in vivo
    • Galloway M.P., Suchowski C.S., Keegan M.J., Hjorth S. Local infusion of the selective 5-HT1b agonist CP-93,129 facilitates striatal dopamine release in vivo. Synapse. 15:1993;90-92.
    • (1993) Synapse , vol.15 , pp. 90-92
    • Galloway, M.P.1    Suchowski, C.S.2    Keegan, M.J.3    Hjorth, S.4
  • 14
    • 0001906905 scopus 로고
    • Differences and similarities among anorectic agents
    • in: S. Garattini, R. Samanin (Ed.), Raven Press, New York
    • S. Garattini, E. Borroni, T. Mennini, R. Samanin, Differences and similarities among anorectic agents, in: S. Garattini, R. Samanin (Ed.), Central Mechanisms of Anorectic Drugs, Raven Press, New York, 1978, pp. 127-141.
    • (1978) Central Mechanisms of Anorectic Drugs , pp. 127-141
    • Garattini, S.1    Borroni, E.2    Mennini, T.3    Samanin, R.4
  • 15
    • 0003099198 scopus 로고
    • Anorectic drugs and brain neurotransmitters
    • in: T. Silverstone (Ed.), Abakon, Berlin
    • S. Garattini, R. Samanin, Anorectic drugs and brain neurotransmitters, in: T. Silverstone (Ed.), Dahlem Workshop on Appetite and Food Intake, Abakon, Berlin, 1976, pp. 83-108.
    • (1976) Dahlem Workshop on Appetite and Food Intake , pp. 83-108
    • Garattini, S.1    Samanin, R.2
  • 16
    • 0026545894 scopus 로고
    • Progress report on the anorexia induced by drugs believed to mimic some of the effects of serotonin on the central nervous system
    • Garattini S., Bizzi A., Codegoni A.M., Caccia S., Mennini T. Progress report on the anorexia induced by drugs believed to mimic some of the effects of serotonin on the central nervous system. Am. J. Clin. Nutr. 55:1992;160S-166S.
    • (1992) Am. J. Clin. Nutr. , vol.55
    • Garattini, S.1    Bizzi, A.2    Codegoni, A.M.3    Caccia, S.4    Mennini, T.5
  • 17
    • 0018248907 scopus 로고
    • Biochemical and behavioral effects of serotonin neurotoxins on the nigro-striatal dopamine system: Comparison of injection sites
    • Giambalvo C.T., Snodgrass S.T. Biochemical and behavioral effects of serotonin neurotoxins on the nigro-striatal dopamine system: comparison of injection sites. Brain Res. 152:1978;555-556.
    • (1978) Brain Res. , vol.152 , pp. 555-556
    • Giambalvo, C.T.1    Snodgrass, S.T.2
  • 18
    • 0030070015 scopus 로고    scopus 로고
    • Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: Implications for serotonin-dopamine interactions
    • Gudelsky G.A., Nash J.F. Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions. J. Neurochem. 66:1996;243-249.
    • (1996) J. Neurochem. , vol.66 , pp. 243-249
    • Gudelsky, G.A.1    Nash, J.F.2
  • 19
    • 0013514965 scopus 로고
    • Dopamine receptor regulation of serotonin release from the rat hippocampus measured by in vivo microdialysis
    • Matsumoto M., Yoshioka M., Togashi H., Saito H. Dopamine receptor regulation of serotonin release from the rat hippocampus measured by in vivo microdialysis. J. Neurochem. 65:1995;S29.
    • (1995) J. Neurochem. , vol.65 , pp. 29
    • Matsumoto, M.1    Yoshioka, M.2    Togashi, H.3    Saito, H.4
  • 20
    • 0013510808 scopus 로고    scopus 로고
    • Systemic administration of the dopamine agonist apomorphine increases serotonin release in rat forebrain
    • Mendlin A., Martin F.J., Reeves A.J., Jacobs B.L. Systemic administration of the dopamine agonist apomorphine increases serotonin release in rat forebrain. Soc. Neu. Abst. 23:1997;1227.
    • (1997) Soc. Neu. Abst. , vol.23 , pp. 1227
    • Mendlin, A.1    Martin, F.J.2    Reeves, A.J.3    Jacobs, B.L.4
  • 21
    • 0024405395 scopus 로고
    • Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine
    • Moghaddam B., Bunney B.S. Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine. J. Neurochem. 53:1989;652-654.
    • (1989) J. Neurochem. , vol.53 , pp. 652-654
    • Moghaddam, B.1    Bunney, B.S.2
  • 22
    • 0018191224 scopus 로고
    • A preliminary study on the behavior and biochemical responses subsequent to the injection of 5,6-dihydroxytryptamine into the substantia nigra of the rat
    • Osborne N.N., Neuhall V., Sontag K.H., Wolfarth S. A preliminary study on the behavior and biochemical responses subsequent to the injection of 5,6-dihydroxytryptamine into the substantia nigra of the rat. Experientia. 34:1978;495-496.
    • (1978) Experientia , vol.34 , pp. 495-496
    • Osborne, N.N.1    Neuhall, V.2    Sontag, K.H.3    Wolfarth, S.4
  • 23
    • 0027532412 scopus 로고
    • Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis
    • Parsons L.H., Justice J.B. Jr. Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Res. 606:1993;195-199.
    • (1993) Brain Res. , vol.606 , pp. 195-199
    • Parsons, L.H.1    Justice J.B., Jr.2
  • 25
    • 0016816599 scopus 로고
    • Fenfluramine: A review. A review of its pharmacological properties and therapeutic efficacy in obesity
    • Pinder R.M., Brogden R.N., Sawyer P.R., Speight T.M., Avery G.S. Fenfluramine: a review. A review of its pharmacological properties and therapeutic efficacy in obesity. Drugs. 10:1975;241-323.
    • (1975) Drugs , vol.10 , pp. 241-323
    • Pinder, R.M.1    Brogden, R.N.2    Sawyer, P.R.3    Speight, T.M.4    Avery, G.S.5
  • 26
    • 0026322577 scopus 로고
    • The effect of four days of continuous striatal microdialysis on indices of dopamine and serotonin neurotransmission in rats
    • Robinson T.E., Camp D.M. The effect of four days of continuous striatal microdialysis on indices of dopamine and serotonin neurotransmission in rats. J. Neurosci. Methods. 40:1991;211-222.
    • (1991) J. Neurosci. Methods , vol.40 , pp. 211-222
    • Robinson, T.E.1    Camp, D.M.2
  • 27
    • 0015393299 scopus 로고
    • The effect of selective lesioning of brain serotonin or catecholamine containing neurons on the anorectic activity of fenfluramine and amphetamine
    • Samanin R., Ghezzi D., Valzelli L., Garattini S. The effect of selective lesioning of brain serotonin or catecholamine containing neurons on the anorectic activity of fenfluramine and amphetamine. Eur. J. Pharmacol. 19:1972;318-322.
    • (1972) Eur. J. Pharmacol. , vol.19 , pp. 318-322
    • Samanin, R.1    Ghezzi, D.2    Valzelli, L.3    Garattini, S.4
  • 28
    • 0016587925 scopus 로고
    • The effect of selective lesioning of brain catecholamine-containing neurons on the activity of various anorectics in the rat
    • Samanin R., Bernasconi S., Garattini S. The effect of selective lesioning of brain catecholamine-containing neurons on the activity of various anorectics in the rat. Eur. J. Pharmacol. 34:1975;373-375.
    • (1975) Eur. J. Pharmacol. , vol.34 , pp. 373-375
    • Samanin, R.1    Bernasconi, S.2    Garattini, S.3
  • 29
    • 0030871421 scopus 로고    scopus 로고
    • Behavioural and neurochemical characteristics of phentermine and fenfluramine administered separately and as a mixture in rats
    • Shoaib M., Baumann M.H., Rothman R.B., Goldberg S.R., Schindler C.W. Behavioural and neurochemical characteristics of phentermine and fenfluramine administered separately and as a mixture in rats. Psychopharmacology. 131:1997;296-306.
    • (1997) Psychopharmacology , vol.131 , pp. 296-306
    • Shoaib, M.1    Baumann, M.H.2    Rothman, R.B.3    Goldberg, S.R.4    Schindler, C.W.5
  • 31
    • 0019194355 scopus 로고
    • Serotoninergic and non-serotoninergic projections from nucleus raphe dorsalis to the caudate putamen complex in the rat, studied by a combined immunofluorescence and fluorescent retrograde axonal labeling technique
    • Steinbusch H.V., Van Der Kooy D., Verhofstad A.A., Pellegrino A. Serotoninergic and non-serotoninergic projections from nucleus raphe dorsalis to the caudate putamen complex in the rat, studied by a combined immunofluorescence and fluorescent retrograde axonal labeling technique. Neurosci. Lett. 19:1980;137-142.
    • (1980) Neurosci. Lett. , vol.19 , pp. 137-142
    • Steinbusch, H.V.1    Van Der Kooy, D.2    Verhofstad, A.A.3    Pellegrino, A.4
  • 32
    • 0022470850 scopus 로고
    • Microdialysis in the study of extracellular levels of aminoacids in the rat brain
    • Tossman U., Ungerstedt U. Microdialysis in the study of extracellular levels of aminoacids in the rat brain. Acta Physiol. Scand. 128:1986;9-14.
    • (1986) Acta Physiol. Scand. , vol.128 , pp. 9-14
    • Tossman, U.1    Ungerstedt, U.2
  • 33
    • 0027317069 scopus 로고
    • Ultrastructure of serotonin-immunoreactive terminals in the core and shell of the rat nucleus accumbens: Cellular substrates for interactions with catecholamine afferents
    • Van Bockstaele E.J., Pickel V.M. Ultrastructure of serotonin-immunoreactive terminals in the core and shell of the rat nucleus accumbens: cellular substrates for interactions with catecholamine afferents. J. Comp. Neurol. 334:1993;603-617.
    • (1993) J. Comp. Neurol. , vol.334 , pp. 603-617
    • Van Bockstaele, E.J.1    Pickel, V.M.2
  • 34
    • 0018890580 scopus 로고
    • Dorsal raphe cells with collateral projections to the caudate-putamen and substantia nigra: A fluorescent retrograde double labelling study in the rat
    • Van Der Kooy D., Hattori T. Dorsal raphe cells with collateral projections to the caudate-putamen and substantia nigra: a fluorescent retrograde double labelling study in the rat. Brain Res. 186:1980;1-7.
    • (1980) Brain Res. , vol.186 , pp. 1-7
    • Van Der Kooy, D.1    Hattori, T.2
  • 35
    • 0021242404 scopus 로고
    • A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination
    • Weintraub M., Hasday J.D., Mushlin A.I., Lockwood D.H. A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination. Arc. Int. Med. 144:1984;1143-1148.
    • (1984) Arc. Int. Med. , vol.144 , pp. 1143-1148
    • Weintraub, M.1    Hasday, J.D.2    Mushlin, A.I.3    Lockwood, D.H.4
  • 36
    • 0026518794 scopus 로고
    • Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
    • Weintraub M., Sundaresan P.R., Madan M., Schuster B., Balder A., Lasagna L., Cox C. Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo. Clin. Pharmacol. Ther. 51:1992;586-594.
    • (1992) Clin. Pharmacol. Ther. , vol.51 , pp. 586-594
    • Weintraub, M.1    Sundaresan, P.R.2    Madan, M.3    Schuster, B.4    Balder, A.5    Lasagna, L.6    Cox, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.