Time-dependent changes of levels of endogenous epidermal growth factor in submandibular glands, in kidneys, and in urine in rats during systemic treatment with EGF

Regulatory Peptides

Volumn 78, Issue 1-3, 1998, Pages 75-82

  Vinter Jensen, Lars ^a,b   Jørgensen, Per E ^a   Thulesen, Jesper ^c   Poulsen, Steen Seier ^c   Nexø, Ebba ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Endogenous; Epidermal growth factor; Exogenous; Time dependence

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORMONE SYNTHESIS; IMMUNOHISTOCHEMISTRY; KIDNEY; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; RAT; SALIVA ANALYSIS; SUBCUTANEOUS DRUG ADMINISTRATION; SUBMANDIBULAR GLAND; TIME; URINALYSIS;

ANIMALS; EPIDERMAL GROWTH FACTOR; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUBMANDIBULAR GLAND; TIME FACTORS;

TRIXIS;

EID: 0032583206     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(98)00126-8     Document Type: Article

References (30)

1. [1] Cohen S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the newborn animal. J Biol Chem 1962;237:1555-62.
2. [2] Gregory H. Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature 1975;257:325-7.
3. [3] Olsen PS, Kirkegaard P, Poulsen SS, Nexø E. Adrenergic effects on exocrine secretion of rat submandibular epidermal growth factor. Gut 1984;25:1234-40.
4. [4] Jørgensen PE, Hilchey SD, Nexø E, Poulsen SS, Quilley CP. Urinary epidermal growth factor is excreted from the rat isolated perfused kidney in the absence of plasma. J Endocrinol 1993;139:227-34.
5. [5] Olsen PS, Poulsen SS, Kirkegaard P, Nexø E. Role of submandibular saliva and epidermal growth factor in gastric cytoprotection. Gastroenterology 1984;87:103-8.
6. [6] Messing EM, Hanson P, Ulrich P, Erturk E. Epidermal growth factor - interactions with normal and malignant urothelium: in vivo and in situ studies. J Urol 1987;138:1329-35.
7. [7] Gresik EW. The granular convoluted tubule (GCT) cell of rodent submandibular glands. Microsc Res Tech 1994;27:1-24.
8. [8] Salido EC, Yen PH, Shapiro LJ, Fisher DA, Barajas L. In situ hybridization of prepro-epidermal growth factor mRNA in the mouse kidney. Am J Physiol 1989;256:F632-8.
9. [9] Tuomela T, Miettinen P, Viinikka L, Perheentupa J. Estrogenandrogen antagonism in the regulation of epidermal growth factor in mouse submandibular salivary gland and kidneys. Life Sci 1990;47:1925-32.
10. [10] Walker P. Thyroxine increases submandibular gland nerve growth factor and epidermal growth factor concentrations precociously in neonatal mice: evidence for thyroid hormone-mediated growth factor synthesis. Pediatr Res 1986;20:281-4.
11. [11] Rogers SA, Miller SB, Hammerman MR. Triiodothyronine stimulates renal epidermal growth factor expression in adult rat. Am J Physiol 1995;268:F128-34.
12. [12] Prigent SA, Lemoine NR. The type 1 (EGFR-related) family of growth factor receptors and their ligands. Prog Growth Factor Res 1992;4:1-24.
13. [13] Barnard JA, Graves Deal R, Pittelkow MR, DuBois R, Cook P, Ramsey GW, Bishop PR, Damstrup L, Coffey RJ. Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family. J Biol Chem 1994;269:22817-22.
14. [14] Vinter-Jensen L, Jørgensen PE, Poulsen SS, Nexø E. The effects of chronic administration of epidermal growth factor (EGF) to rats on the levels of endogenous EGF in the submandibular glands and in the kidneys. Regul Pept 1996;67:179-85.
15. [15] Jørgensen PE, Vinter-Jensen L, Nexø E. An immunoassay designed to quantitate different molecular forms of rat urinary epidermal growth factor with equimolar potency: application on fresh rat urine. Scand J Clin Lab Invest 1996;56:25-36.
16. [16] Vinter-Jensen L, Smerup M, Jørgensen PE, Juhl CO, Ørntoft T, Poulsen SS, Nexø E. Chronic treatment in the rat with epidermal growth factor stimulates growth of the urinary tract. Urol Res 1996;24:15-21.
17. [17] Nexø E, Jørgensen PE, Thim L, Roepstorff P. Purification and characterization of a low and a high molecular weight form of epidermal growth factor from rat urine. Biochim Biophys Acta 1990;1037:388-93.
18. [18] Nexø E, Jørgensen E, Hansen MR. Human epidermal growth factor - on molecular forms present in urine and blood. Regul Pept 1992;42:75-84.
19. [19] Vinter-Jensen L, Flyvbjerg A, Nexø E. Systemic treatment with EGF causes organ growth concomitant with reduced circulating levels of IGF-I and IGFBP-3. Time-dependent changes in female rats. Growth Regul 1997;7.
20. [20] Hansson HA, Tunhall S. Epidermal growth factor and insulin-like growth factor I are localized in different compartments of salivary gland duct cells. Immunohistochemical evidence. Acta Physiol Scand 1988;134:383-9.
21. [21] Hiramatsu M, Kashimata M, Takayama F, Minami N. Developmental changes in and hormonal modulation of epidermal growth factor concentration in the rat submandibular gland. J Endocrinol 1994;140:357-63.
22. [22] Pascall JC, Saunders J, Blakeley DM, Laurie MS, Brown KD. Tissue-specific effects of castration and ovariectomy on murine epidermal growth factor and its mRNA. J Endocrinol 1989;121:501-6.
23. [23] Schaudies RP, Grimes J, Davis D, Koldovsky O. Modulation of immunoreactive epidermal growth factor levels in the submandibular gland, pancreas, liver, kidney and gastrointestinal tract of suckling rats by cortisone and tri-iodothyronine. J Endocrinol 1991;131:95-100.
24. [24] Perheentupa J, Lakshmanan J, Fisher DA. Epidermal growth factor in neonatal mouse urine: maturative effect of thyroxine. Pediatr Res 1984;18:1080-4.
25. [25] Fujieda M, Murata Y, Hayashi H, Kambe F, Matsui N, Seo H. Effect of thyroid hormone on epidermal growth factor gene expression in mouse submandibular gland. Endocrinology 1993;132:121-5.
26. [26] Corcoran JM, Waters MJ, Eastman CJ, Jorgensen G. Epidermal growth factor: effect on circulating thyroid hormone levels in sheep. Endocrinology 1986;119:214-7.
27. [27] Jørgensen PE, Poulsen SS, Nexø E. Distribution of i.v. administered epidermal growth factor in the rat. Regul Pept 1988;23:161-9.
28. [28] Vinter-Jensen L, Juhl CO, Frystyk J, Dajani EZ, Oksbjerg N, Flyvbjerg A. The effect of epidermal growth factor (EGF) on circulating levels of insulin-like growth factor (IGF) and IGF binding proteins (IGFBPs) in adult Goettingen minipigs. J Endocrinol 1996;151:401-7.
29. [29] Gubits RM, Shaw PA, Gresik EW, Onetti Muda A, Barka T. Epidermal growth factor gene expression is regulated differently in mouse kidney and submandibular gland. Endocrinology 1986;119:1382-7.
30. [30] Gow CB, Phillips PA. Epidermal growth factor as a diuretic in sheep. J Physiol Lond 1994;477:27-33.