Structure of the glycosylphosphatidylinositol-anchor of the trans-sialidase from Trypanosoma cruzi metacyclic trypomastigote forms

Molecular and Biochemical Parasitology

Volumn 97, Issue 1-2, 1998, Pages 123-131

  Agusti, Rosalía ^a   Couto, Alicia S ^a   Campetella, Oscar ^b   Frasch, Alberto C C ^b   De Lederkremer, Rosa M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

Author keywords

Ceramide; GPI anchor; Trans sialidase; Trypanosoma cruzi

Indexed keywords

CERAMIDE; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE PROTEIN; SIALIDASE;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

BACILLUS THURINGIENSIS; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0032583154     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00137-6     Document Type: Article

References (31)

1. Campetella O., Sanchez D., Cazzulo J.J., Frasch A.C.C. A superfamily of Trypanosoma cruzi surface antigens. Parasitol. Today. 8:1992;378-381.
2. Parodi A.J., Pollevick G.D., Mautner M., Buschiazzo A., Sanchez D.O., Frasch A.C.C. Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi. EMBO. J. 11:1992;1705-1710.
3. Schenkman S., Eichinger D. Trypanosoma cruzi trans-sialidase and cell invasion. Parasitol. Today. 9:1993;218-222.
4. Schenkman S., Jiang M., Hart G.W., Nussenzweig V. A novel cell surface trans-sialidase of Trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells. Cell. 65:1991;1117-1125.
5. Pollevick G.D., Sanchez D.O., Campetella O. et al. Members of the SAPA/trans-sialidase protein family have identical N-terminal sequences and a putative signal peptide. Mol. Biochem. Parasitol. 59:1993;171-174.
6. Bertello L.E., Andrews N.W., Lederkremer R.M. Developmentally regulated expression of ceramide in Trypanosoma cruzi. Mol. Biochem. Parasitol. 79:1996;142-151.
7. Acosta Serrano A., Schenkman S., Yoshida N., Mehlert A., Richardson J.M., Ferguson M.A.J. The lipid structure of the glycosylphosphatidylinositol-anchored mucin-like sialic acid acceptors of Trypanosoma cruzi changes during parasite differentiation from epimastigotes to infective metacyclic trypomastigote forms. J. Biol. Chem. 270:1995;27244-27253.
8. Güther M.L.S., Cardoso de Almeida M.L., Yoshida N., Ferguson M.A.J. Structural studies on the GPI membrane anchor of Trypanosoma cruzi 1G7 antigen. J. Biol. Chem. 267:1992;6820-6828.
9. Previato J.O., Jones C., Xavier M.T. et al. Structural characterization of the major GPI-membrane anchored glycoprotein from epimastigote forms of Trypanosoma cruzi Y-strain. J. Biol. Chem. 270:1995;7241-7250.
10. Camargo M.M., Almeida I.C., Pereira M.E.S., Ferguson M.A.J., Travassos L.R., Gazzinelli R.T. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages. J. Immunol. 158:1997;5890-5901.
11. Couto A.S., Lederkremer R.M., Colli W., Alves M.J.M. The glycosylphosphatidylinositol anchor of the trypomastigote-specific Tc-85 glycoprotein from Trypanosoma cruzi. Metabolic-labeling and structural studies. Eur. J. Biochem. 217:1993;597-602.
12. Agusti R., Couto A.S., Campetella O.E., Frasch A.C.C., Lederkremer R.M. The trans-sialidase of Trypanosoma cruzi is anchored by two different lipids. Glycobiology. 7:1997;731-735.
13. Chiari E, Camargo EP. Culturing and cloning of Trypanosoma cruzi. In: Morel CM, editor. Genes and antigens of parasites: A laboratory manual. 2nd ed. Rio de Janeiro: Fundaçao Oswaldo Cruz, 1984; 23-26.
14. Lederkremer R.M., Lima C., Ramirez M.I., Ferguson M.A.J., Homans S.W., Thomas-Oates J. Complete structure of the glycan of lipopeptidophosphoglycan from Trypanosoma cruzi epimastigotes. J. Biol. Chem. 266:1991;23670-23675.
15. Ferguson M.A.J. Glycosyl-phosphatidylinositol membrane anchors: The tale of a tail. Biochem. Soc. Trans. 20:1992;243-256.
16. Ferguson MAJ. GPI membrane anchors: isolation and analysis. In: Fukuda M, Kobata A, editors. Glycobiology: A practical approach. New York: Oxford University Press, 1993;349-383.
17. Rosenberg I., Prioli R.P., Ortega-Barria E., Pereira M.E.A. Stage-specific phospholipase C-mediated release of Trypanosoma cruzi neuraminidase. Mol. Biochem. Parasitol. 46:1991;303-306.
18. Chaves L.B., Briones M.R.S., Schenkman S. Trans-sialidase from Trypanosoma cruzi epimastigotes is expressed at the stationary phase and is different from the enzyme expressed in trypomastigotes. Mol. Biochem. Parasitol. 61:1993;96-106.
19. Uhrig M.L., Couto A.S., Alves M.J.M., Colli W., Lederkremer R.M. Trypanosoma cruzi: nitrogenous-base-containing phosphatides in trypomastigote forms. Exp. Parasitol. 87:1997;8-19.
20. Ferguson M.A.J., Homans S.W., Dwek R.A., Rademacher T.W. GPI moiety that anchors T. brucei variant surface glycoprotein to the membrane. Science. 239:1988;753-759.
21. Field M.C., Menon A.K., Cross G.A.M. A glycosylphosphatidylinositol protein anchor from procyclic stage Trypanosoma brucei: lipid structure and biosynthesis. EMBO. J. 10:1991;2731-2739.
22. Ferguson M.A.J. Site of palmitoylation of a phospholipase C-resistant glycosylphosphatidylinositol membrane anchor. Biochem. J. 284:1992;297-300.
23. Ferguson M.A.J., Murray P., Rutherford H., McConville M.J. A simple purification of procyclic acidic repetitive protein and demonstration of a sialylated glycosyl-phosphatidylinositol membrane anchor. Biochem. J. 291:1993;51-55.
24. Schneider P., Ferguson M.A.J., McConville M.J., Mehlert A., Homans S.W., Bordier C. Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease. J. Biol. Chem. 265:1990;16955-16964.
25. Stadler J., Keenan T.W., Bauer G., Gerisch G. The contact site A glycoprotein of Dictyostelium discoideum carries a phospholipid anchor of a novel type. EMBO. J. 8:1989;371-377.
26. da Silva A.M., Klein C. Characterization of a GPI-degrading activity in Dyctiostelium discoideum membranes. Exp. Cell. Res. 185:1989;464-472.
27. Gonçalves M.F., Umezawa E.S., Katzin A.M. et al. Trypanosoma cruzi: Shedding of surface antigens as membrane vesicles. Exp. Parasitol. 72:1991;43-53.
28. Abuin G., Couto A.S., Lederkremer R.M. et al. Trypanosoma cruzi: The Tc-85 surface glycoprotein shed by trypomastigotes bears a modified glycosylphosphatidylinositol anchor. Exp. Parasitol. 82:1996;290-297.
29. Holder A.A. Glycosylation of the variant surface antigens of Trypanosoma brucei. Curr. Top. Microbiol. Immunol. 117:1985;57-92.
30. Couto A.S., Gonçalves M.F., Colli W., Lederkermer R.M. The N-linked carbohydrate chain of the 85-kilodalton glycoprotein from Trypanosoma cruzi trypomastigotes contains sialyl, fucosyl and galactosyl (α1-3)galactose units. Mol. Biochem. Parasitol. 39:1990;101-108.
31. Almeida I.C., Ferguson M.A.J., Schenkman S., Travassos L.R. Lytic anti-α-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosylphosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi. Biochem. J. 304:1994;793-802.