Role of the first aspartate residue of the 'YxDTDS' motif of ∅29 DNA polymerase as a metal ligand during both TP-primed and DNA-primed DNA synthesis

Journal of Molecular Biology

Volumn 283, Issue 3, 1998, Pages 633-642

  Saturno, Javier ^a   Lázaro, José M ^a   Blanco, Luis ^a   Salas, Margarita ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

Catalysis; DNA synthesis; Protein primed DNA replication; Site directed mutagenesis; 29 DNA polymerase

Indexed keywords

ASPARTIC ACID; DNA POLYMERASE; EXONUCLEASE; LIGAND; MAGNESIUM ION; MANGANESE; METAL;

ARTICLE; BACTERIOPHAGE; DNA SYNTHESIS; ENZYME ACTIVE SITE; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

UNIDENTIFIED BACTERIOPHAGE;

EID: 0032582787     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2121     Document Type: Article

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