Enantioselective synthesis of α-hydroxy carboxylic acids: Direct conversion of α-oxocarboxylic acids to enantiomerically enriched α-hydroxy carboxylic acids via neighboring group control

Tetrahedron Letters

Volumn 39, Issue 31, 1998, Pages 5501-5504

  Wang, Zhe ^a   La, Brittany ^a,c   Fortunak, Joseph M ^a   Meng, Xian Jun ^a,b   Kabalka, George W ^b  

^a DUPONT COMPANY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c WESLEYAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; REDUCING AGENT;

ARTICLE; CHEMICAL REACTION; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0032581676     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01162-9     Document Type: Article

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24. 1H-NMR studies (peaks at δ = 6.12 and 6.09) revealed 96% ee.