메뉴 건너뛰기




Volumn 71, Issue 1, 1998, Pages 48-54

Effects of dexmedetomidine, an α2-adrenoceptor agonist, on renal sympathetic nerve activity, blood pressure, heart rate and central venous pressure in urethane-anesthetized rabbits

Author keywords

Baroreceptor reflex system; Central 2 adrenergic agonist; Dexmedetomidine; Hemodynamics; Neural blood pressure control; Peripheral 2 adrenoceptor

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; DEXMEDETOMIDINE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; IMIDAZOLE DERIVATIVE; MEDETOMIDINE; URETHAN;

EID: 0032580789     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(98)00061-7     Document Type: Article
Times cited : (60)

References (26)
  • 2
    • 0016431584 scopus 로고
    • Effects of clonidine on baroreceptor function in anesthetized dogs
    • Antonaccio, M.J., Robson, R.D., Burrel, R., 1975. Effects of clonidine on baroreceptor function in anesthetized dogs. Eur. J. Pharmacol. 30, 6-14.
    • (1975) Eur. J. Pharmacol. , vol.30 , pp. 6-14
    • Antonaccio, M.J.1    Robson, R.D.2    Burrel, R.3
  • 5
  • 6
    • 0028116955 scopus 로고
    • Oral dexmedetomedine preserves baroreceptor function and decreases anesthetic requirements of halothane-anesthetized dogs
    • Devcic, A., Schmeling, W.T., Kampine, J.P., Warltiere, D.C., 1994. Oral dexmedetomedine preserves baroreceptor function and decreases anesthetic requirements of halothane-anesthetized dogs. Anesthesiology 81, 419-430.
    • (1994) Anesthesiology , vol.81 , pp. 419-430
    • Devcic, A.1    Schmeling, W.T.2    Kampine, J.P.3    Warltiere, D.C.4
  • 7
    • 0018578718 scopus 로고
    • Evidence for two distinct types of postsynaptic α-adrenoceptor in vascular smooth muscle in vivo
    • Drew, G.M., Whiting, S.B., 1979. Evidence for two distinct types of postsynaptic α-adrenoceptor in vascular smooth muscle in vivo. Br. J. Pharmacol. 67, 207-215.
    • (1979) Br. J. Pharmacol. , vol.67 , pp. 207-215
    • Drew, G.M.1    Whiting, S.B.2
  • 8
    • 0025267255 scopus 로고
    • Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla
    • Ernsberger, P., Giuliano, R., Willette, R.N., Reis, D.J., 1990. Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla. J. Pharmacol. Exp. Ther. 253, 408-418.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 408-418
    • Ernsberger, P.1    Giuliano, R.2    Willette, R.N.3    Reis, D.J.4
  • 10
    • 0025158165 scopus 로고
    • Hemodynamic effects of dexmedetomidine, an α2-adrenergic agonist, in autonomically denervated dogs
    • Flacke, J.W., Flacke, W.E., Bloor, B.C., Mclntee, D.F., 1990. Hemodynamic effects of dexmedetomidine, an α2-adrenergic agonist, in autonomically denervated dogs. J. Cardiovasc. Pharmacol. 16, 616-623.
    • (1990) J. Cardiovasc. Pharmacol. , vol.16 , pp. 616-623
    • Flacke, J.W.1    Flacke, W.E.2    Bloor, B.C.3    Mclntee, D.F.4
  • 12
    • 0019144389 scopus 로고
    • Clonidine in the central nervous system: Site and mechanism of hypotensive action
    • Isaac, L., 1980. Clonidine in the central nervous system: site and mechanism of hypotensive action. J. Cardiovasc. Pharmacol. 2, S5-S19.
    • (1980) J. Cardiovasc. Pharmacol. , vol.2
    • Isaac, L.1
  • 16
    • 0020325999 scopus 로고
    • Prejunctional modulation of noradrenaline release by α2-adrenoceptors: Physiological and pharmacological implication in the cardiovascular system
    • Langer, S.Z., Shepperson, N.B., 1982. Prejunctional modulation of noradrenaline release by α2-adrenoceptors: physiological and pharmacological implication in the cardiovascular system. J. Cardiovasc. Pharmacol. 4, S35-S40.
    • (1982) J. Cardiovasc. Pharmacol. , vol.4
    • Langer, S.Z.1    Shepperson, N.B.2
  • 17
    • 0002697894 scopus 로고
    • Loewy, A.D., Spyer, K.M. (Eds.), Oxford Univ. Press, New York
    • Loewy, A.D., 1990. In: Loewy, A.D., Spyer, K.M. (Eds.), Central Regulation of Autonomic Functions. Oxford Univ. Press, New York, pp. 88-103.
    • (1990) Central Regulation of Autonomic Functions , pp. 88-103
    • Loewy, A.D.1
  • 18
    • 0024565007 scopus 로고
    • Effect of pertussis-toxin treatment on postjunctional alpha-1 and alpha-2 adrenoceptor function in cardiovascular system of the pithed rat
    • Nichols, A.J., Motley, E.D., Ruffolo, R.R., 1989. Effect of pertussis-toxin treatment on postjunctional alpha-1 and alpha-2 adrenoceptor function in cardiovascular system of the pithed rat. J. Pharmacol. Exp. Ther. 249, 203-209.
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 203-209
    • Nichols, A.J.1    Motley, E.D.2    Ruffolo, R.R.3
  • 19
    • 0029796874 scopus 로고    scopus 로고
    • Renal sympathetic nerve activity after dexmedetomidine in nerve-intact and baroreceptor-denervated rabbits
    • Oku, S., Benson, K.T., Hirakawa, M., Goto, H., 1996. Renal sympathetic nerve activity after dexmedetomidine in nerve-intact and baroreceptor-denervated rabbits. Anesth. Analg. 83, 477-481.
    • (1996) Anesth. Analg. , vol.83 , pp. 477-481
    • Oku, S.1    Benson, K.T.2    Hirakawa, M.3    Goto, H.4
  • 20
    • 0030969122 scopus 로고    scopus 로고
    • 3.5% hypertonic saline produces sympathetic activation in hemorrhaged rabbits
    • Seki, K., Aibiki, M., Ogura, S., 1997. 3.5% hypertonic saline produces sympathetic activation in hemorrhaged rabbits. J. Auton. Nerv. Syst. 64 (1), 49-56.
    • (1997) J. Auton. Nerv. Syst. , vol.64 , Issue.1 , pp. 49-56
    • Seki, K.1    Aibiki, M.2    Ogura, S.3
  • 21
    • 0026062301 scopus 로고
    • An imidazoline-specific mechanism for the hypotensive effect of clonidine: A study with yohimbine and idazoxan
    • Tibirica, E., Feldman, J., Mermet, C., Gonon, F., Bousquet, P., 1991. An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan. J. Pharmacol. Exp. Ther. 256, 606-613.
    • (1991) J. Pharmacol. Exp. Ther. , vol.256 , pp. 606-613
    • Tibirica, E.1    Feldman, J.2    Mermet, C.3    Gonon, F.4    Bousquet, P.5
  • 22
    • 0021396341 scopus 로고
    • Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents
    • Unnnerstall, J.A., Kopajtic, T.A., Kuhar, M.J., 1984. Distribution of α2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents. Brain Res. Rev. 7, 69-101.
    • (1984) Brain Res. Rev. , vol.7 , pp. 69-101
    • Unnnerstall, J.A.1    Kopajtic, T.A.2    Kuhar, M.J.3
  • 23
    • 0023903938 scopus 로고
    • Characterization of the selectivity, specifity and potency of medetomidine as an α2-adrenoceptor agonist
    • Virtanen, R., Savola, J.-M., Saano, V., Nyman, L., 1988. Characterization of the selectivity, specifity and potency of medetomidine as an α2-adrenoceptor agonist. Eur. J. Pharmacol. 150, 9-14.
    • (1988) Eur. J. Pharmacol. , vol.150 , pp. 9-14
    • Virtanen, R.1    Savola, J.-M.2    Saano, V.3    Nyman, L.4
  • 24
    • 0016211656 scopus 로고
    • Action of clonidine on baroreceptor reflexes in conscious dogs
    • Walland, A., Kobinger, W., Csongrady, A., 1974. Action of clonidine on baroreceptor reflexes in conscious dogs. Eur. J. Pharmacol. 26, 184-190.
    • (1974) Eur. J. Pharmacol. , vol.26 , pp. 184-190
    • Walland, A.1    Kobinger, W.2    Csongrady, A.3
  • 25
    • 0028139292 scopus 로고
    • Clonidine has comparable effects on spontaneous sympathetic activity and Aδ- And C-fiber-mediated somatosympathetic reflexes in dogs
    • Wang, C., Knowles, M.G., Chakrabarti, M.K., Whitwam, J.G., 1994. Clonidine has comparable effects on spontaneous sympathetic activity and Aδ- and C-fiber-mediated somatosympathetic reflexes in dogs. Anesthesiology 81, 710-717.
    • (1994) Anesthesiology , vol.81 , pp. 710-717
    • Wang, C.1    Knowles, M.G.2    Chakrabarti, M.K.3    Whitwam, J.G.4
  • 26
    • 0026134114 scopus 로고
    • Anesthetic and hemodynamic effects of dexmedetomidine during isoflurane anesthesia in a canine model
    • Weitz, D.J., Foster, S.D., Waugaman, W.R., Katz, R.L., Bloor, B.C., 1991. Anesthetic and hemodynamic effects of dexmedetomidine during isoflurane anesthesia in a canine model. Nurse Anesth. 2, 19-27.
    • (1991) Nurse Anesth. , vol.2 , pp. 19-27
    • Weitz, D.J.1    Foster, S.D.2    Waugaman, W.R.3    Katz, R.L.4    Bloor, B.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.