Epidermal mosaicism producing localised acne: Somatic mutation in FGFR2

Lancet

Volumn 352, Issue 9129, 1998, Pages 704-705

  Munro, Colin S ^a,b   Wilkie, Andrew O M ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FIBROBLAST GROWTH FACTOR RECEPTOR;

ACNE; ACROCEPHALOSYNDACTYLY; ADOLESCENT; ARTICLE; CASE REPORT; DNA SEQUENCE; GENE AMPLIFICATION; GERM LINE; HUMAN; MALE; MOSAICISM; PRIORITY JOURNAL; SOMATIC MUTATION;

EID: 0032578269     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)60820-3     Document Type: Article

References (6)

1. Happle R. Mosaicism in human skin: understanding the patterns and mechanisms. Arch Dermatol 1993; 129: 1460-70.
2. Palier AS, Syder AJ, Chan Y-M, et al. Genetic and clinical mosaicism in a type of epidermal nevus. N EnglJ M ed 1994; 331: 1408-15.
3. Orlow SJ. Cutaneous findings in craniofacial malformation syndromes. Arch Dermatol 1992; 128: 1379-86.
4. Wilkie AOM. Craniosynostosis: genes and mechanisms. Hum Mol Genet 1997; 6: 1647-56.
5. Moloney DM, Slaney SF, Oldridge M , et al. Exclusive paternal origin of new mutations in Apert syndrome. Nat Genet 1996; 13: 48-53.
6. Werner S, Weinberg W, Liao X, et al. Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EM BO J 1993; 12: 2635-43.