Sevoflurane suppresses behavioral response in the rat formalin test: Combination with intrathecal lidocaine produced profound suppression of the response

Neuroscience Letters

Volumn 248, Issue 2, 1998, Pages 124-126

  Hao, Shuanglin ^a   Ogawa, Hidemichi ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Formalin test; Lidocaine; Sevoflurane

Indexed keywords

FORMALDEHYDE; LIDOCAINE; SEVOFLURANE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MIXTURE; DRUG POTENTIATION; FOREBRAIN; HYPERALGESIA; INHALATIONAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE INJURY;

ANESTHETICS, INHALATION; ANESTHETICS, LOCAL; ANIMALS; BEHAVIOR, ANIMAL; DRUG SYNERGISM; FORMALDEHYDE; HINDLIMB; INJECTIONS, SPINAL; LIDOCAINE; MALE; METHYL ETHERS; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032577666     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00282-1     Document Type: Article

References (16)

1. Abram S.E., Yaksh T.L. Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat. Anesthesiology. 80:1994;383-391.
2. Beilin B., Nemirovsky A.Y., Zeidel A., Maibord E., Zelman V., Katz R.L. Systemic physostigmine increases the antinociceptive effect of spinal morphine. Pain. 70:1997;217-221.
3. Coderre T.J., Vaccarino A.L., Melzack R. Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection. Brain Res. 535:1990;155-158.
4. Dickenson A.H., Sullivan A.F. Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin. Pain. 30:1987;349-360.
5. McQuay H.J., Carroll D., Moore R.A. Postoperative orthopaedic pain-the effect of opiate premedication and local anaesthetic blocks. Pain. 33:1988;291-295.
6. Nagy I., Woolf C.J. Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations: implications for the development of novel centrally acting analgesics. Pain. 64:1996;59-70.
7. O'Connor T.C., Abram S.E. Halothane enhances suppression of spinal sensitization by intrathecal morphine in the rat formalin test. Anesthesiology. 81:1994;1277-1283.
8. O'Connor T.C., Abram S.E. Inhibition of nociception-induced spinal sensitization by anesthetic agents. Anesthesiology. 82:1995;259-266.
9. Ogasawara H. Effects of sevoflurane anesthesia on norepinephrine metabolism in rat brain. Masui. 41:1992;78-85.
10. Ogasawara H., Takahashi S., Kudo T., Kudo M., Ishihara H., Matsuki A. Effects of sevoflurane anesthesia on serotonin metabolism in rat brain. Masui. 42:1993;1412-1417.
11. Plummer J.L., Cmielewski P.L., Gourlay G.K., Owen H., Cousins M.J. Antinociceptive and motor effects of intrathecal morphine combined with intrathecal clonidine, noradrenaline, carbachol or midazolam in rats. Pain. 49:1992;145-152.
12. Sawynok J., Reid A. Neurotoxin-induced lesions to central serotonergic, noradrenergic and dopaminergic systems modify caffeine-induced antinociception in the formalin test and locomotor stimulation in rats. J. Pharmacol. Exp. Ther. 277:1996;646-653.
13. Schouenborg J., Dickenson A. Long-lasting neuronal activity in rat dorsal horn evoked by impulses in cutaneous C fibres during noxious mechanical stimulation. Brain Res. 439:1988;56-63.
14. Sotgiu M.L., Lacerenza M., Marchettini P. Selective inhibition by systemic lidocaine of noxious evoked activity in rat dorsal horn neurons. NeuroReport. 2:1991;425-428.
15. Sun W.Z., Shyu B.C., Shieh J.Y. Nitrous oxide or halothane, or both, fail to suppress c-fos expression in rat spinal cord dorsal horn neurones after subcutaneous formalin. Br. J. Anaesth. 76:1996;99-105.
16. Yamamota T., Yaksh T.L. Comparison of the antinociceptive effects of pre and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology. 77:1992;757-763.