Noradrenaline neurotoxin DSP-4 effects on sleep and brain temperature in the rat

Neuroscience Letters

Volumn 248, Issue 2, 1998, Pages 93-96

  Del C González, Mónica M ^a   Debilly, Gabriel ^a   Valatx, Jean Louis ^a  

^a INSERM   (France)

Author keywords

Brain temperature; Locus coeruleus; N (2 Chloroethyl) N ethyl 2 bromobenzylamine; Neurotoxic lesion; Paradoxical sleep; Rat; Slow wave sleep

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; NEUROTOXIN; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TEMPERATURE; CONTROLLED STUDY; LIGHT DARK CYCLE; LOCUS CERULEUS; MALE; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; NORADRENERGIC NERVE; PRIORITY JOURNAL; RAT; REM SLEEP; SLOW WAVE SLEEP;

ADRENERGIC AGENTS; ANIMALS; BENZYLAMINES; BODY TEMPERATURE; BRAIN; DARKNESS; LIGHT; LOCUS COERULEUS; MALE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SLEEP; SLEEP, REM; TIME FACTORS; WAKEFULNESS;

EID: 0032577659     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00333-4     Document Type: Article

References (24)

1. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J. Neurosci. 1:1981;876-886.
2. Berger B., Hervé D., Dolphin A., Barthelemy C., Gay M., Tassin J.P. Genetically determined differences in noradrenergic input to the brain cortex: a histochemical and biochemical study in two inbred strains of mice. Neuroscience. 4:1979;877-888.
3. Cirelli, C. and Tononi, G., Changes in gene expression in DSP-4 treated rats revealed by mRNA differential display, Soc. Neurosci., 23 (1997) 689 (abstract).
4. Denoyer M., Sallanon M., Buda C., Delhomme G., Dittmar A., Jouvet M. The posterior hypothalamus is responsible for the increase of brain temperature during paradoxical sleep. Exp. Brain Res. 84:1991;326-334.
5. Dooley D.J., Bittiger H., Hauser K. L, Bischoff S.F., Waldmeier P.C. Alteration of central alpha2-and beta-adrenergic receptors in the rat after DSP-4, a selective noradrenergic neurotoxin. Neuroscience. 9:1983;889-898.
6. Féty R., Misère V., Lambàs-Señas L., Renaud B. Central and peripheral changes in catecholamine-synthesizing enzyme activities after systemic administration of the neurotoxin DSP-4. Eur. J. Pharmacol. 124:1986;197-202.
7. Fritschy J.M., Grzanna R. Immunohistochemical analysis of the neurotoxic effects of the DSP-4 identifies two populations of noradrenergic axon terminals. Neuroscience. 30:1989;181-197.
8. González M.M.C., Valatx J.L., Debilly G. Role of the locus coeruleus in the sleep rebound following two different sleep deprivation methods in the rat. Brain Res. 740:1996;215-226.
9. Hallman H., Sundström E., Jonsson G. Effects of the noradrenaline neurotoxin DSP-4 on monoamine neurons and their transmitter turnover in rat CNS. J. Neural Transm. 60:1984;89-102.
10. Jones, B.E., Basic mechanisms of sleep-wake states. In M.H. Kryger, T. Roth and W.C. Dement (Eds.), Principles and Practice of Sleep Medicine, WB Saunders, London, 1994, pp. 145-162.
11. Jouvet M. The role of monoamines and acetylcholine-containing neurons. Ergeb. Physiol. Biol. Chem. Pharmakol. 64:1972;166-307.
12. Jouvet M. Paradoxical sleep mechanisms. Sleep. 17:1994;S77-S83.
13. La Manna J.C., Harik S.I., Light A.I., Rosenthal M. Norepinephrine depletion alters cerebral oxidative metabolism in the 'active' state. Brain Res. 204:1981;87-101.
14. Logue M.P., Growdon J.H., Coviella I.L.G., Wurtman R.J. Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats. Life Sci. 37:1985;403-409.
15. Magistretti, P.J., Pellerin, L. and Martin, J.L., Brain energy metabolism. An integrated cellular perspective. In F.E. Bloom and D.J. Kupfer (Eds.), Psychopharmacology: the Fourth Generation of Progress, Raven, New York, 1995, pp. 657-670.
16. Matsuyama S., Coindet J., Mouret J. 6-hydroxydopamine intracisternale et sommeil chez le rat. Brain Res. 57:1973;85-95.
17. Monti J.M., D'Angelo L., Jantos H., Barbeito L., Abó V. Effect of DSP-4, a noradrenergic neurotoxin, on sleep and wakefulness and sensitivity to drugs acting on adrenergic receptors in the rat. Sleep. 11:1988;370-377.
18. Nakamura K., Thoenen H. Hypothermia induced by intraventricular administration of 6-hydroxydopamine in rats. Eur. J. Pharmacol. 16:1971;46-54.
19. Roussel B., Pujol J.F., Jouvet M. Effets des lésions du tegmentum pontique sur les états de sommeil chez le rat. Arch. Ital. Biol. 114:1976;188-209.
20. Sakai, K., Neurons responsible for paradoxical sleep. In A. Wauquier et al. (Eds.), Sleep: Neurotransmitters and Neuromodulators, Raven, New York, 1985, pp. 29-42.
21. Silverman, A-J. and Pickard, G.E., The hypothalamus. In Emson (Ed.), Chemical Neuroanatomy, Raven, New York, 1983, pp. 295-336.
22. Theron C.N., Devilliers A.S., Taljaard J.J.F. Effects of DSP-4 on monoamine and monoamine metabolite levels and on beta-adrenoceptor binding kinetics in the rat brain at different times after administration. Neurochem. Res. 18:1993;1321-1327.
23. Touret M., Valatx J.L., Jouvet M. The locus coeruleus: a quantitative and genetic study in mice. Brain Res. 250:1982;353-357.
24. Valatx J.L., Bugat R. Facteurs génétiques dans le déterminisme du cycle veille-sommeil chez la souris. Brain Res. 69:1974;315-330.