Convergent synthesis of N-linked glycopeptides on a solid support

Journal of the American Chemical Society

Volumn 120, Issue 16, 1998, Pages 3915-3927

  Roberge, J Y ^a   Beebe, X ^a   Danishefsky, S J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDE;

ARTICLE; METHODOLOGY; PEPTIDE SYNTHESIS; POLYMERIZATION; PROTEIN INTERACTION; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0032577049     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9740071     Document Type: Article

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55. Iodonium bis(sym-collidine) perchlorate: Under nitrogen, iodine (775 mg, 3 mmol) was added to a suspension of silver bis(sym-collidine) perchlorate and sym-collidine (45 μL, 0.34 mmol) in 12 mL of chloroform (dried over activated basic alumina). The mixture was vigorously stirred for 15 min and the bright yellow suspension was filtered over flame-dried Celite under dry nitrogen. Ether (10 mL) was added and the faintly green precipitate was filtered over sintered glass under dried nitrogen, washed with ether and dried under reduced pressure. Yield ∼ 1 g.