Vagal efferent and afferent innervation of the rat esophagus as demonstrated by anterograde DiI and DiA tracing: Focus on myenteric ganglia

Journal of the Autonomic Nervous System

Volumn 70, Issue 1-2, 1998, Pages 92-102

  Neuhuber, Winfried L ^a,b   Kressel, Michael ^a   Stark, Andrea ^a   Berthoud, Hans Rudolf ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Anterograde tracing; Dorsal motor nucleus; Enteric nervous system; Local peristalsis control; Nodose ganglion; Nucleus ambiguus

Indexed keywords

CARBOCYANINE; TRACER;

AMBIGUUS NUCLEUS; ANIMAL TISSUE; ARTICLE; ESOPHAGUS; HISTOCHEMISTRY; INNERVATION; MALE; MOTONEURON NUCLEUS; NERVE ENDING; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH FUNDUS; VAGUS NERVE;

ANIMALS; CARBOCYANINES; ESOPHAGUS; FLUORESCENT DYES; GANGLIA, AUTONOMIC; HISTOCYTOCHEMISTRY; MALE; MEDULLA OBLONGATA; MOTOR NEURONS; MYENTERIC PLEXUS; NEURONS, AFFERENT; NEURONS, EFFERENT; NODOSE GANGLION; PYRIDINIUM COMPOUNDS; RATS; SPINAL NERVE ROOTS; VAGUS NERVE;

EID: 0032575138     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(98)00034-4     Document Type: Article

References (39)

1. Altschuler S.M., Bao X., Bieger D., Hopkins D.A., Miselis R.R. Viscerotopic representation of the upper alimentary tract in the rat: sensory ganglia and nuclei of the solitary and spinal trigeminal tracts. J. Comp. Neurol. 283:1989;248-268.
2. Ambalavanar R., Morris R. Fluoro-Gold injected either subcutaneously or intravascularly results in extensive retrograde labelling of CNS neurones having axons terminating outside the blood-brain barrier. Brain Res. 505:1989;171-175.
3. Barrett R.T., Bao X., Miselis R.R., Altschuler S.M. Brain stem localization of rodent esophageal premotor neurons revealed by transneuronal passage of Pseudorabies virus. Gastroenterology. 107:1994;728-737.
4. Berthoud H.-R. Morphological analysis of vagal input to gastrin releasing peptide and vasoactive intestinal peptide containing neurons in the rat glandular stomach. J. Comp. Neurol. 370:1996;61-70.
5. Berthoud, H.-R., Neuhuber, W.L., 1994. Distribution and morphology of vagal afferents and efferents supplying the digestive system. In: Taché, Y., Wingate, D.L., Burks, T.F. (Eds.), Innervation of the Gut. Pathophysiological Implications. CRC Press, Boca Raton, FL, pp. 43-66.
6. Berthoud H.-R., Powley T.L. Vagal afferent innervation of the rat fundic stomach: morphological characterization of the gastric tension receptor. J. Comp. Neurol. 319:1992;261-276.
7. Berthoud H.-R., Jedrzejewska A., Powley T.L. Simultaneous labelling of vagal innervation of the gut and afferent projections from the visceral forebrain with DiI injected into the dorsal vagal complex in the rat. J. Comp. Neurol. 301:1990;65-79.
8. Berthoud H.-R., Kressel M., Neuhuber W.L. An anterograde tracing study of the vagal innervation of rat liver, portal vein and biliary system. Anat. Embryol. 186:1992;431-442.
9. Berthoud H.-R., Patterson L.M., Neumann F., Neuhuber W.L. Distribution and structure of vagal afferent intraganglionic laminar endings (IGLEs) in the rat gastrointestinal tract. Anat. Embryol. 195:1997;183-191.
10. Bieger D., Hopkins D.A. Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat: the nucleus ambiguus. J. Comp. Neurol. 262:1987;546-562.
11. Cecio A., Califano G. Neurohistological observations on the oesophageal innervation of rabbit. Z. Zellforsch. 83:1967;30-39.
12. Christensen J., Rick G.A., Soll D.J. Intramural nerves and interstitial cells revealed by the Champy-Maillet stain in the opossum esophagus. J. Auton. Nerv. Syst. 19:1987;137-151.
13. Collman P.I., Tremblay L., Diamant N.E. The central vagal efferent supply to the esophagus and lower esophageal sphincter of the cat. Gastroenterology. 104:1993;1430-1438.
14. Connors N.A., Sullivan J.M., Kubb K.S. An autoradiographic study of the distribution of fibers from the dorsal motor nucleus of the vagus to the digestive tube of the rat. Acta Anat. 115:1983;266-271.
15. Cunningham E.T. Jr., Sawchenko P.E. Central neural control of esophageal motility: a review. Dysphagia. 5:1990;35-51.
16. Fryscak T., Zenker W., Kantner D. Afferent and efferent innervation of the rat esophagus. A tracing study with horseradish peroxidase and nuclear yellow. Anat. Embryol. 170:1984;63-70.
17. Green T., Dockray G.J. Calcitonin gene-related peptide and substance P in afferents to the upper gastrointestinal tract in the rat. Neurosci. Lett. 76:1987;151-156.
18. Gruber H. Über Struktur und Innervation der quergestreiften Muskulatur des Oesophagus der Ratte. Z. Zellforsch. 91:1968;236-247.
19. Gruber H. Motor innervation of the striated oesophagus muscle. J. Neurol. Sci. 36:1978;41-53.
20. Holst M.-C., Kelly J.B., Powley T.L. Vagal preganglionic projections to the enteric nervous system characterized with phaseolus vulgaris-leucoagglutinin. J. Comp. Neurol. 381:1997;81-100.
21. Hudson L.C., Cummings J.F. The origins of innervation of the esophagus of the dog. Brain Res. 326:1985;125-136.
22. Kalia M., Mesulam M.-M. Brain stem projections of sensory and motor components of the vagus complex in the cat: II. Laryngeal, tracheobronchial, pulmonary, cardiac, and gastrointestinal branches. J. Comp. Neurol. 193:1980;523-553.
23. Khurana R.K., Petras J.M. Sensory innervation of the canine esophagus, stomach and duodenum. Am. J. Anat. 192:1991;293-306.
24. Kressel M., Berthoud H.-R., Neuhuber W.L. Vagal innervation of the rat pylorus: an anterograde tracing study using carbocyanine dyes and laser scanning confocal microscopy. Cell Tiss. Res. 275:1994;109-123.
25. Neuhuber W.L. Sensory vagal innervation of the rat esophagus and cardia: a light and electron microscopic anterograde tracing study. J. Auton. Nerv. Syst. 20:1987;243-255.
26. Neuhuber W.L., Appelt M., Polak J.M., Baier-Kustermann W., Abelli L., Ferri G.-L. Rectospinal neurons: cell bodies, pathways, immunocytochemistry and ultrastructure. Neuroscience. 56:1993;367-378.
27. Neuhuber W.L., Wörl J., Berthoud H.-R., Conte B. NADPH-diaphorase-positive nerve fibers associated with motor endplates in the rat esophagus: new evidence for co-innervation of striated muscle by enteric neurons. Cell Tiss. Res. 276:1994;23-30.
28. Ottaviani G. Osservazioni istoanatomiche e sperimentali sulla innervazione dell'esofago di alcuni mammiferi. Z. Zellforsch. 27:1938;393-429.
29. Paxinos, G., Watson, C., 1992. The Rat Brain in Stereotaxic Coordinates, 2nd edn. Academic Press, Sydney.
30. Powley T.L., Berthoud H.-R. A fluorescent labelling strategy for staining the enteric nervous system. J. Neurosci. Meth. 36:1991;9-15.
31. Phillips R.J., Baronowsky E.A., Powley T.L. Afferent innervation of the gastrointestinal tract smooth muscle by the hepatic branch of the vagus. J. Comp. Neurol. 384:1997;248-270.
32. Rodrigo J., Hernandez C.J., Vidal M.A., Pedrosa J.A. Vegetative innervation of the esophagus: II. Intraganglionic laminar endings. Acta Anat. 92:1975;79-100.
33. Samarasinghe D.D. Some observations on the innervation of the striated muscle in the mouse esophagus - an electron microscope study. J. Anat. 112:1972;173-184.
34. Schemann M., Grundy D. Electrophysiological identification of vagally innervated enteric neurons in guinea pig stomach. Am. J. Physiol. 263:1992;G709-G718.
35. Sengupta J.N., Kauvar D., Goyal R.K. Characteristics of vagal esophageal tension-sensitive afferent fibers in the opossum. J. Neurophysiol. 61:1989;1001-1010.
36. Whitmore I. The ultrastructure of oesophageal striated muscle in the guinea-pig and marmoset. Cell Tiss. Res. 234:1983;365-376.
37. Wörl J., Mayer B., Neuhuber W.L. Nitrergic innervation of the rat esophagus: focus on motor endplates. J. Auton. Nerv. Syst. 49:1994;227-233.
38. Wörl J., Mayer B., Neuhuber W.L. Spatial relationships of enteric nerve fibers to vagal motor terminals and the sarcolemma in motor endplates of the rat esophagus: a confocal laser scanning and electron-microscopic study. Cell Tiss. Res. 287:1997;113-118.
39. Zheng H., Lauve A., Patterson L.M., Berthoud H.-R. Limited excitatory local effector function of gastric vagal afferent intraganglionic terminals in rats. Am. J. Physiol. 273:1997;G661-G669.