Extracellular proton alters the divalent cation binding affinity in a cyclic nucleotide-gated channel pore

FEBS Letters

Volumn 440, Issue 1-2, 1998, Pages 199-202

  Rho, Seong Hwan ^a   Park, Chul Seung ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Binding affinity; Cyclic nucleotide gated channel; Extracellular proton; Glutamate residue

Indexed keywords

CATION CHANNEL; DIVALENT CATION; GLUTAMIC ACID; MEMBRANE PROTEIN; PROTON; RETINAL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CATTLE; CONTROLLED STUDY; NONHUMAN; OOCYTE; PH; PRIORITY JOURNAL; RETINA; SODIUM CURRENT; SODIUM TRANSPORT; XENOPUS;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CATIONS, DIVALENT; CATTLE; ELECTROPHYSIOLOGY; ELECTROSTATICS; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; ION CHANNELS; MUTATION; OOCYTES; PROTONS; SODIUM; STRONTIUM; TITRIMETRY; XENOPUS LAEVIS;

BOVINAE;

EID: 0032573393     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01353-2     Document Type: Article

References (8)

1. [1] Eismann, E., Muller, F., Heinemann, S.H. and Kaupp, U.B. (1994) Proc. Natl. Acad. Sci. USA 91, 1109-1113.
2. [2] Goulding, E.H., Tibbs, G.R., Liu, D. and Siegelbaum, S.A. (1994) Nature 364, 61-64.
3. [3] Heginbotham, L., Abramson, T. and MacKinnon, R. (1992) Science 258, 1152-1155.
4. [4] Liman, E.R., Tytgat, J. and Hess, P. (1992) Neuron 9, 861-871.
5. [5] Martell, A.E., and Smith, R.M. (1994) in: Critical Stability Constants, Vol. 1, pp. 204-271, Plenum Press, New York, NY.
6. [6] Park, C.-S. and MacKinnon, R. (1995) Biochemistry 34, 13328-13333.
7. [7] Root, M. and MacKinnon, R. (1993) Neuron 11, 459-466.
8. [8] Root, M. and MacKinnon, R. (1994) Science 265, 1852-1856.