Enzymatic reaction with unnatural substrates: DNA photolyase (Escherichia coii) recognizes and reverses thymine [2+2] dimers in the DNA strand of a DNA/PNA hybrid duplex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 22, 1998, Pages 12902-12905

  Ramaiah, Danaboyina ^a,c   Kan, Yongzhi ^a   Koch, Troels ^b   Ørum, Henrik ^b   Schuster, Gary B ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b PNA Diagnostics A S   (Denmark)

^c REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBODIPYRIMIDINE PHOTOLYASE; DIMER; DNA; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; PERMANGANATE POTASSIUM; PHOSPHORUS 32; THYMINE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DNA STRAND; ENZYME MECHANISM; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE; ULTRAVIOLET IRRADIATION;

BASE SEQUENCE; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; DNA; DNA REPAIR; ESCHERICHIA COLI; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGOPEPTIDES; PYRIMIDINE DIMERS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032573067     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.22.12902     Document Type: Article

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