An efficient new protocol for the formation of unsymmetrical Tri-and tetrasubstituted ureas

Tetrahedron Letters

Volumn 39, Issue 35, 1998, Pages 6267-6270

  Batey, Robert A ^a   Santhakumar, V ^a   Yoshina Ishii, Chiaki ^a   Taylor, Scott D ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

IMIDAZOLE DERIVATIVE; UREA DERIVATIVE;

ALKYLATION; ARTICLE; ISOLATION PROCEDURE; PURIFICATION; SYNTHESIS; TEMPERATURE;

EID: 0032572851     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01330-6     Document Type: Article

References (12)

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4. 4. Katritzky, A. R.; Pleynet, D. P. M.; Yang, B. J. Org. Chem. 1997, 62, 4155-4158.
5. 5. 1-(Dimethylcarbamoyl)-3-methylimidazolium chloride was previously synthesized from dimethylcarbamoyl chloride and N-methylimidazole, but was reported to be unreactive toward reaction with p-nitro-aniline, see: Dadali, V. A.; Lapshin, S. A.; Litvinenko, L. M.; Simanenko, Yu, S.; Tishchenko, N. A. J. Org. Chem. USSR (Engl. Transl.) 1978, 14, 2076-2082.
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8. 8. (a) Guilbé-Jampel, E.; Bram, G.; Wakselman, M.; Vilkas M. Synthetic Commun., 1973, 3, 111-114.
9. (b) Watkins, B. E.; Rapoport, H. J. Org. Chem. 1982, 47, 4471-4477.
10. (c) Kamijo, T.; Yamamoto, R.; Harada, H.; Iizuka, K. Chem. Pharm. Bull. 1982, 30, 4242-4244.
11. 9. Staab, H. A.; Benz, W. Liebigs Ann. Chem. 1961, 648, 72-82.
12. +) 266.1419. found 266.1427.