3-Deoxyl-D-myo-inositol 1-phosphate, 1-phosphate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth

Journal of Medicinal Chemistry

Volumn 41, Issue 18, 1998, Pages 3303-3306

  Qiao, L ^a   Nan, F ^a   Kunkel, M ^a   Gallegos, A ^a   Powis, G ^a   Kozikowski, A P ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEOXYPHOSPHATIDYLINOSITOL; ETHER PHOSPHOLIPID; INOSITOL DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; INOSITOL PHOSPHATE; LIPID;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LETTER; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; ANIMAL; ARTICLE; CANCER TRANSPLANTATION; CATTLE; CELL CULTURE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; PHYSIOLOGY; SYNTHESIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATTLE; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; INOSITOL PHOSPHATES; LIPIDS; MICE; NEOPLASM TRANSPLANTATION; PHOSPHONIC ACIDS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0032572649     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980254j     Document Type: Letter

References (30)