Effect of propofol on oxidative stress in an in vitro model of anoxia- reoxygenation in the rat brain

Brain Research

Volumn 800, Issue 1, 1998, Pages 136-144

  De La Cruz, J P ^a   Villalobos, M A ^a   Sedeno G ^a   Sanchez De La Cuesta F ^a  

^a UNIVERSITY OF MÁLAGA   (Spain)

Author keywords

Glutathione; Ischemia; Lipid peroxidation; Oxidative stress; Propofol; Reperfusion

Indexed keywords

ALPHA TOCOPHEROL; GLUTATHIONE; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOXIA; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN OXYGEN CONSUMPTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REOXYGENATION; SPECTROFLUOROMETRY; THROMBOCYTE AGGREGATION; TISSUE INJURY;

ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HYPOXIA, BRAIN; LIPID PEROXIDATION; MALE; OXYGEN CONSUMPTION; PROPOFOL; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0032572591     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00516-2     Document Type: Article

References (32)

1. L. Aarts, R. Van der Hee, I. Dekker, J. De Jong, H. Langemeijer, A. Bast, The widely used anaesthetic agent propofol can replace alpha-tocopherol as antioxidant, FEBS 357 (1995) 83-85, Suppl. 1.
2. H. Arai, K. Machii, T. Tsuda, K. Kogure, T. Watanabe, M. Nakano, Possible involvement of iron-dependent lipid peroxidation in the delayed neuronal death of rat brain after a transient ischemia, J. Clin. Biochem. Nurt. 3 (1987) 227-232.
3. F. Block, M. Kunkel, K.H. Sontag, Posttreatment with EPC-K1, an inhibitor of lipid peroxidation and of phospholipase A2 activity, reduces functional deficits after global ischemia in rats, Brain Res. Bull. 36 (1995) 257-260.
4. H.B. Bossman, B.D. Hemsworth, Structure and Function of Nervous Tissue, 2nd edn., Vol. 3, Academic Press, London, 1969, pp. 1-24.
5. P.H. Chan, J.W. Schmidley, R.A. Fishman, S.M. Longar, Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals, Neurology 34 (1984) 315-320.
6. I.D. Cockshott, Propofol pharmacokinetics and metabolism: an overview, Postgrad. Med. J. 61 (1985) 45-50, Suppl. 3.
7. R.J. Davis, G.B. Bulkley, R.J. Traystman, Role of oxygen free radicals in focal brain ischemia, Fed. Proc. 46 (1987) 799.
8. J. De Alba, A. Cárdenas, J.C. Leza, M.A. Moro, I. Lizasoain, P. Lorenzo, Acetylsalicylic acid-induced neuroprotection in an in vitro model of brain ischemia-reperfusion, Methods Find. Exp. Clin. Pharmacol. 19 (1997) 116, Suppl. A.
9. J.P. De La Cruz, J.A. Carmona, M.V. Paez, E. Blanco, F. Sánchez De La Cuesta, Propofol inhibits in vitro platelet aggregation in human whole blood, Anaesth. Analg. 84 (1997) 919-921.
10. J.P. De La Cruz, T. Carrasco, G. Ortega, F. Sánchez De La Cuesta, Inhibition of ferrous-induced lipid peroxidation by pyrimido-pyrimidine derivatives in human liver membranes, Lipids 27 (1992) 192-194.
11. J.P. De La Cruz, M.A. Villalobos, T. Carrasco, J.M. Smith-Agreda, F. Sanchez De La Cuesta, The pyrimido-pyrimidine derivative RA-642 protects from brain injury in a combined model of permanent focal ischemia and global ischemia-reperfusion, Brain Res. 597 (1992) 250-256.
12. M.S. Desole, G. Esposito, R. Migheli, S. Fresu et al., Allopurinol protects against manganese-induced oxidative stress in the striatum and in the brainstem of the rat, Neurosci. Lett. 492 (1995) 1-4.
13. O. Eriksson, P. Pollesello, E.N. Saris, Inhibition of lipid peroxidation in isolated rat liver mitochondria by the general anaesthetic propofol, Biochem. Pharmacol. 44 (1992) 391-393.
14. L. Flohe, W.A. Gunzel, Assay of glutathione peroxidase, Methods Enzymol. 105 (1984) 114-121.
15. M. Gerlach, P. Riederer, M.B.H. Youdim, Neuroprotective therapeutic strategies. Comparison of experimental and clinical results, Biochem. Pharmacol. 50 (1995) 1-16.
16. T.R. Green, S.R. Bennett, V.M. Nelson, Specificity and properties of propofol as an antioxidant free radical scavenger, Toxicol. Appl. Pharmacol. 129 (1994) 163-169, Suppl. 1.
17. P. Hans, C. Deby, G. Deby-Dupont, B. Vrijens, A. Albert, M. Lamy, Effect of propofol on in vitro lipid peroxidation induced by different free radical generating systems: a comparison with vitamin E, J. Neurosurg. Anaesthesiol. 8 (1996) 154-158, Suppl. 2.
18. H. Hara, H. Kato, K. Kogure, Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus, Brain Res. 510 (1990) 335-338.
19. L. Hillered, L. Ernster, Respiratory activity of isolated rat brain mitochondria following in vitro exposure to oxygen radicals, J. Cereb. Blood Flow Metab. 3 (1983) 207-214.
20. L. Hillered, L. Ernster, B.K. Siesjö, Influence of in vitro lactid acidosis and hypercapnia on respiratory activity of isolated rat brain mitochondria, J. Cereb. Blood Flow Metab. 4 (1984) 430-437.
21. L. Hillered, B.K. Siesjö, K.E. Arfors, Mitochondrial response to transient forebrain ischemia and recirculation in the rat, J. Cereb. Blood Flow Metab. 4 (1984) 438-446.
22. P.J. Hissin, R. Hill, A fluorimetric method of determination of oxidized and reduced glutathione on tissues, Anal. Biochem. 74 (1976) 214-226.
23. K. Kogure, H. Arai, K. Abe, M. Nakano, Free radical damage of the brain following ischemia, Prog. Brain Res. 63 (1985) 237-259.
24. O. Lowry, H. Rosebrough, A. Farr, R. Randall, Protein measurement with the Polin Phenol reagent, J. Biol. Chem. 193 (1951) 265-275.
25. S.D. Michowiz, E. Melamed, E. Pikarsky, Z.H. Rappaport, Effect of ischemia induced by middle cerebral artery occlusion on superoxide activity in rat brain, Stroke 21 (1991) 1613-1617.
26. P.G. Murphy, D.S. Myers, M.J. Webster et al., The antioxidant potential of propofol (2,6-diisopropylphenol), Br. J. Anaesth. 68 (1992) 613-618.
27. E. Musacchio, V. Rizzoli, M. Bianchi, A. Bindoli, L. Galzigna, Antioxidant action of propofol on liver microsomes, mitochondria and brain synaptosomes in the rat, Pharmacol. Toxicol. 69 (1991) 75-77.
28. I. Nakahara, H. Kikuchi, W. Taki, S. Nishi, M. Kito, Y. Yonekawa, Y. Goto, N. Ogata, Degradation of mitochondrial phospholipids during experimental cerebral ischemia in rats, J. Neurochem. 57 (1991) 839-844.
29. M. Spranger, S. Krempien, S. Schwab, S. Donneberg, W. Hacke, Superocide dismutase activity in serum of patients with acute cerebral ischemic injury, Stroke 28 (1997) 2425-2428.
30. G. Sutherland, R. Bose, D. Louw, C. Minski, Global elevation of brain superoxide dismutase activity following forebrain ischemia in rat, Neurosci. Lett. 128 (1991) 3169-3172.
31. M.A. Villalobos, J.P. De La Cruz, T. Carrasco, J.M. Smith-Agreda, F. Sanchez De La Cuesta, Effects of α-tocopherol on lipid peroxidation and mitochondrial reduction of tetraphenyl tetrazolium in the rat brain, Brain Res. Bull. 33 (1994) 313-318.
32. M. Warholm, C. Guthemberg, C. von Bahr, B. Mannervik, Glutathione transferase from human liver, Methods Enzymol. 113 (1985) 449-503.