Complement-mediated pulmonary xenograft injury: Studies in swine-to- primate orthotopic single lung transplant models

Transplantation

Volumn 65, Issue 8, 1998, Pages 1084-1093

  Yeatman, Mark ^a   Daggett, Casey W ^a   Parker, William ^a   Byrne, Guerard W ^b   Logan, John S ^b   Platt, Jeffrey L ^a   Davis, R Duane ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Nextran   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD59 ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; BABOON; COMPLEMENT ACTIVATION; GRAFT VERSUS HOST REACTION; IMMUNOPATHOGENESIS; LUNG ARTERY; LUNG BIOPSY; LUNG BLOOD FLOW; LUNG TRANSPLANTATION; LUNG VASCULAR RESISTANCE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SWINE; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD; ANTIGENS, CD55; ANTIGENS, CD59; COBRA VENOMS; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT SYSTEM PROTEINS; GRAFT SURVIVAL; HEMODYNAMIC PROCESSES; HUMANS; LUNG TRANSPLANTATION; PAPIO; PULMONARY CIRCULATION; SWINE; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 0032571862     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199804270-00013     Document Type: Article

References (38)

1. Hosenpud JD, Novick RJ, Breen TJ, Keck B, Daily P. The Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Report - 1995. J Heart Lung Transplant 1995; 14: 805.
2. Evans RW, Orians CE, Ashe NL. The potential supply of organ donors: an assessment of the efficiency of organ procurement efforts in the United States. JAMA 1992; 267: 239.
3. Kallis P, Al-Saady N, Bennett D, Treasure T. Clinical use of intravascular oxygenation [Letter]. Lancet 1991; 337(8740): 549.
4. Daggett C, Yeatman M, Chen E, et al. Transgenic swine-to-primate pulmonary xenotransplantation. Surg Forum 1996; XLVII: 413.
5. Tavakoli R, Devaux JY, Nonnenmacher L, Louvel A, Weill B, Houssin D. Discordant lung xenograft rejection in the rat. Transplantation 1992; 53(1): 235.
6. Platt JL, Vercellotti GM, Dalmasso AP, et al. Transplantation of discordant xenografts: a review of progress. Immunol Today 1990; 11(12): 450.
7. Platt JL. Hyperacute xenograft rejection. Austin, TX: RG Landes Co., 1995.
8. Perper RJ, Najarian JS. Experimental renal heterotransplantation. I. In widely divergent species. Transplantation 1966; 4: 377.
9. Cook WA, Klausner SK, Sinha S, Kikkawa Y, Veith FJ. A new look at hyperacute rejection. Ann Thorac Surg 1972; 13(4): 388.
10. Pierson RN III. Pig-to-primate lung xenografts: are they hyperacutely rejected? Xeno 1995; 3(4): 61.
11. Gammie J, Kawai A, Pham S, et al. Influence of panel-reactive antibody on survival and rejection after lung transplantation. J Heart Lung Transplant 1997; 16(4): 408.
12. Kaplon RJ, Platt JL, Kwiatkowski PA, et al. Absence of hyperacute rejection in pig-to-primate orthotopic pulmonary xenografts. Transplantation 1995; 59: 410.
13. Leventhal JR, Dalmasso AP, Cromwell JW, et al. Prolongation of cardiac xenograft survival by depletion of complement. Transplantation 1993; 55(4): 857.
14. Byrne G, McCurry K, Martin M, Platt J, Logan J. Development and analysis of transgenic pigs expressing the human complement regulatory proteins CD59 and DAF. Transplant Proc 1996; 28(2): 759.
15. McCurry K, Kooyman D, Alvarado C, et al. Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury. Nature Med 1995; 1(5): 423.
16. Wallwork J, Jones K, Cavarocchi N, Hakim M, Higenbottam TW. Distant procurement of organs for clinical heart-lung transplantation using a single flush technique. Transplantation 1987; 44: 654.
17. Kimblad PO, Steen S. Eliminating the strong pulmonary vaso-constriction caused by Euro-Collins solution. Ann Thorac Surg 1994; 58(3): 728.
18. Platt JL, LeBien TW, Michael AF. Stages of renal ontogenesis identified by monoclonal antibodies reactive with lymphohemopoietic differentiation antigens. J Exp Med 1983; 157: 155.
19. Platt JL, Michael AF. Retardation of fading and enhancement of intensity of immunofluorescence by p-phenylenediamine. J Histochem Cytochem 1983; 31: 840.
20. Parker W, Bruno D, Holzknecht ZE, Platt JL. Characterization and affinity isolation of xenoreactive human natural antibodies. J Immunol 1994; 153(8): 3791.
21. Platt JL, Turman MA, Noreen HJ, Fischel RJ, Bolman RM, Bach FH. An ELISA assay for xenoreactive natural antibodies. Transplantation 1990; 49: 1000.
22. Collins B, Cotterell A, McCurry K, et al. Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection. J Immunol 1995; 154: 5500.
23. Mayer M. Complement and complement fixation. In: Kabat E, Mayer M, eds. Experimental immunohistochemistry. Springfield, IL: Thomas, 1961: 133.
24. Gaither T, Ailing D, Frank M. A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement. J Immunol 1974; 113(2): 574.
25. Riquet M, Waldmann T, Le Pimpec-Barthes F, et al. Sheep lung as xenograft oxygenator of human blood: an ex vivo study. Xenotransplantation 1995; 2: 32.
26. Pierson RN III, Dunning JJ, Konig WK, Tew DN, Braidley PC, Wallwork J. Mechanisms governing the pace and character of pig heart-lung rejection by human blood. Transplant Proc 1994; 26(4): 2337.
27. Pierson RN III, Kaspar-König W, Tew DN, et al. Profound pulmonary hypertension characteristic of pig lung rejection by human blood is mediated by xenoreactive antibody independent of complement. Transplant Proc 1995; 27(1): 274.
28. Pierson RN III, Young VK, Kaspar-König W, White DJG, Wallwork J. Expression of human complement regulatory protein may protect pig lung against hyperacute rejection by human blood. J Heart Lung Transplant 1995; S94: 233.
29. Holguin MH, Wilcox LA, Belnshaw NJ, Rosse WF, Parker CJ. Relationship between the membrane inhibitor of reactive lysis and the erythrocyte phenotypes of paroxysmal nocturnal hemoglobinuria. J Clin Invest 1989; 84: 1387.
30. Dalmasso AP, Vercellotti GM, Platt JL, Bach FH. Inhibition of complement-mediated endothelial cell cytotoxicity by decay-accelerating factor: potential for prevention of xenograft hyperacute rejection. Transplantation 1991; 52(3): 530.
31. van den Berg CW, Morgan BP. Complement-inhibiting activities of human CD59 and analogues from rat, sheep, and pig are not homologously restricted. J Immunol 1994; 152: 4095.
32. Collins BH, Chari RS, Magee JC, et al. Immunopathology of porcine livers perfused with blood of humans with fulminant hepatic failure. Transplant Proc 1995; 27(1): 280.
33. Miyagawa S, Hirose H, Shirakura R, et al The mechanism of discordant xenograft rejection. Transplantation 1988; 46: 825.
34. Hancock WW, Blakely ML, van der Werf W, Bach FH. Rejection of guinea pig cardiac xenografts post-cobra venom factor therapy is associated with infiltration by mononuclear cells secreting interferon-gamma and diffuse endothelial activation. Transplant Proc 1993; 25: 2932.
35. Ratliff N, Young WJ, Hackel D, Mikat E, Wilson J. Pulmonary injury secondary to extracorporeal circulation: an ultrastructural study. J Thorac Cardiovasc Surg 1973; 65(3): 425.
36. Till G, Ward P. Lung injury secondary to chemotactic factor-induced leukocyte activation. Agents Actions Suppl 1983; 12: 383
37. Kirklin JK, Westaby S, Blackstone EH, Kirklin JW, Chenowith DE, Pacifico AD. Complement and the damaging effects of cardiopulmonary bypass. J Thorac Cardiovasc Surg 1983; 86: 845.
38. Pierson RI, Parker R. Thromboxane mediates pulmonary vaso-constriction and contributes to cytotoxicity in pig lungs perfused with fresh human blood. Transplant Proc 1996; 28(2): 625.