Determinants of Clara cell protein (CC16) concentration in serum: A reassessment with two different immunoassays

Clinica Chimica Acta

Volumn 272, Issue 2, 1998, Pages 101-110

  Hermans, Cedric ^a   Aly, Osman ^a   Nyberg, Britt Inger ^b   Peterson, Christer ^b   Bernard, Alfred ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b Diagnostics Res and Devmt Asthma   (Sweden)

Author keywords

Body mass index; Clara cell protein (CC16 CC10 CCSP); Fluorescence enzyme immunoassay; Latex immunoassay; Lipids; Lung marker; Smoking

Indexed keywords

CLARA CELL PROTEIN; MARKER; POLYCLONAL ANTIBODY; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; BODY MASS; CLARA CELL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOASSAY; KIDNEY FUNCTION; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; SEX DIFFERENCE; SMOKING;

ADOLESCENT; ADULT; AGED; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; PROTEINS; SENSITIVITY AND SPECIFICITY; SMOKING; UTEROGLOBIN;

LIA; NICOTIANA TABACUM;

EID: 0032571773     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(98)00006-0     Document Type: Article

References (29)

1. [1] Singh G, Singh J, Katyal SL et al. Identification, cellular localization, isolation and characterization of human Clara cell-specific 10 kDa protein. J Histochem Cytochem 1988;36:73-80.
2. [2] Bernard A, Dumont X, Roels HA et al. The molecular mass and concentration of protein 1 or Clara cell protein in biological fluids: a reappraisal. Clin Chim Acta 1993;223:189-91.
3. [3] Bernard A, Marchandise FX, Depelchin S, Lauwerys R, Sibillle Y. Clara cell protein in serum and bronchoalveolar lavage. Eur Respir J 1995;5:1231-8.
4. [4] Hermans C, Bernard A. Clara cell protein (CC16): characteristics and potential applications as biomarker of lung toxicity. Biomarkers 1996;1:3-8.
5. [5] Bernand A, Roels HA, Lauwerys R et al. Human urinary protein 1: evidence for identity with the Clara cell protein and occurrence in respiratory tract and urogenital tract secretions. Clin Chim Acta 1992;20:239-49.
6. [6] Okutani R, Itoh Y, Hirata H, Kasahara T, Mukaida N, Kawai T. Simple and high-yield purification of urine protein 1 using immunoaffinity chromatography: evidence for the identity of urine protein 1 and human Clara cell 10-kilodalton protein. J Chromatogr 1992;577:25-35.
7. [7] Bernard A, Gonzalez-Lorenzo JM, Siles E, Trujillano G, Lauwerys R. Early decrease of serum Clara cell in silica-exposed workers. Eur Respir J 1994;7:1932-7.
8. [8] Bernard A, Roels HA, Buchet J-P, Lauwerys R. Decrease of serum Clara cell protein in smokers [Letter]. Lancet 1992;339:1620.
9. [9] Bernard A, Roels HA, Buchet J-P, Lauwerys R. Serum Clara cell protein: An indicator of bronchial cell dysfunction caused by tobacco smoking. Environ Res 1994;66:96-104.
10. [10] Shijubo N, Itoh Y, Yamaguchi T et al. Serum and BAL Clara cell 10 kDa protein (CC10) levels and CC10 positive bronchiolar cells are decreased in smokers. Eur Respir J 1997;10:1108-14.
11. [11] Lumsden AB, McLean AMc, Lamb D. Goblet and Clara cell of human distal airways, evidence for smoking induced changes in their number. Thorax 1984;39:844-9.
12. [12] Nomori H, Horio H, Fuyuno G, Kobayashi R, Morinaga S, Hirabayashi Y. Protein 1 (Clara cell protein) serum levels in healthy subjects and patients with bacterial pneumonia. Am J Respir Crit Care Med 1995;152:746-50.
13. [13] Nomori H, Horio H, Takagi M, Kobayashi R, Hirabayashi Y. Clara cell protein correlation with hyperlipidemia. Chest 1996;110:680-4.
14. [14] Bernard A, Lauwerys R, Noël A, Vandeleene B, Lambert A. Determination by latex immunoassay of protein 1 in normal and pathological urine. Clin Chim Acta 1991;201:213-6.
15. [15] Itoh Y, Ishii S, Okutani R, Asano Y, Kawai T. Protein 1: its purification and application in clinical medicine. J Clin Lab Anal 1993;7:394-400.
16. [16] Nomori H, Horio H, Kobayashi R, Morinaga S, Hirabayashi Y. Protein 1 (Clara cell protein) serum levels in lung cancer patients receiving chemotherapy. Eur Respir J 1995;8:1654-7.
17. [17] Nomori H, Kobayashi R, Iga R, Fuyuno G, Morinaga S, Torikata C. Clinicopathological examination of the relation between Clara cells and smoking. Kyobu Geka 1994;47:888-91.
18. [18] Boyd MR. Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung. Nature 1977;269:713-5.
19. [19] Suzuki E, Takahashi Y, Aida S, Kimula Y, Ito Y, Miura T. Alteration in surface of Clara cells and pulmonary cytochrome P-450 level in rats exposed to ozone. Toxicology 1992;71:223-32.
20. [20] Bernard A, Thielemans N, Lauwerys R, Vandeleene B, Lambert A. The renal handling of protein 1 (Clara cell protein): effect of age, sex and renal dysfunction. Contrib Nephrol 1993;101:66-70.
21. [21] Jorens PG, Sibille Y, Goulding NJ et al. Potential role of Clara cell protein, an endogenous phospholipase A2 inhibitor, in acute lung injury. Eur Respir J 1995;8:1647-53.
22. [22] Dierynck I, Bernard A, Roels H, De Ley M. Potent inhibition of both human interferon gamma production and biologic activity by the Clara cell protein CC16. Am J Respir Cell Mol Biol 1995;12:205-10.
23. [23] Lesur O, Bernard A, Arsalane K et al. Clara cell protein (CC16) induces a phospholipase A2-mediated inhibition of fibroblasts migration in vitro. Am J Respir Crit Care Med 1995;152:290-7.
24. [24] Haughton MA, Mason RS. Immunonephelometric assay of vitamin D-binding protein. Clin Chem 1992;38:1796-801.
25. [25] Sharma A, Artiss J, Strandbergh D, Zak B. The turbid specimen as an analytical medium: hemoglobin determination as a model. Clin Chim Acta 1985;147:7-14.
26. [26] Borque L, Yago M, Mar C, Rodriguez C. Turbidimetry of rheumatoid factor in serum with a centrifugal analyzer. Clin Chem 1986;32:124-9.
27. [27] Siedel J, Schiefer S, Rosseneu M et al. Immunoturbidimetric method for routine determinations of apolipoproteins A-I, A-II, and B in normo- and hyperlipemic sera compared with immunonephelometry. Clin Chem 1988;34:1821-5.
28. [28] Delanghe J, Chapelle JP, El Allaf M, De Buyzere M. Quantitative turbidimetric assay for determining myoglobin evaluated. Ann Clin Biochem 1991;28:474-9.
29. [29] Bernard A, Lauwerys R. Continuous-flow system for automation of latex immunoassay by particle counting. Clin Chem 1983;29:1007-11.