Molecular approaches for production of pravastatin, a HMG-CoA reductase inhibitor: Transcriptional regulation of the cytochrome P450(sca) gene from Streptomyces carbophilus by ML-236B sodium salt and phenobarbital

Gene

Volumn 210, Issue 1, 1998, Pages 109-116

  Watanabe, Ichiro ^a   Serizawa, Nobufusa ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Actinomycetes; DNA binding protein; Induction; Recombinant DNA; Repression; Transcription

Indexed keywords

COMPACTIN; CYTOCHROME P450; DNA; DNA BINDING PROTEIN; HELIX LOOP HELIX PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PHENOBARBITAL; PRAVASTATIN; SODIUM;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; DRUG SYNTHESIS; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE INDUCTION; GENE MUTATION; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DNA BINDING; STREPTOMYCES; TRANSCRIPTION REGULATION;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); STREPTOMYCES CARBOPHILUS; STREPTOMYCES LIVIDANS;

EID: 0032571447     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00041-9     Document Type: Article

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