Prevalences of resistance to seven antimicrobials among fecal Escherichia coli of swine on thirty-four farrow-to-finish farms in Ontario, Canada

Preventive Veterinary Medicine

Volumn 34, Issue 4, 1998, Pages 265-282

  Dunlop, R H ^a,c   McEwen, S A ^a   Meek, A H ^a   Black, W D ^a   Friendship, R M ^a   Clarke, R C ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b Health of Animals Laboratory   (Canada)

^c DEPARTMENT OF AGRICULTURE AND FOOD WESTERN AUSTRALIA   (Australia)

Author keywords

Diseases; Drug resistance; Escherichia coli; Herd health; Hydrophobic grid membrane filter; Microbiological; Pig

Indexed keywords

ANTIINFECTIVE AGENT;

ANIMAL; ANIMAL DISEASE; ANIMAL HUSBANDRY; ANTIBIOTIC RESISTANCE; ARTICLE; CANADA; DRUG EFFECT; ENTEROBACTER INFECTION; ESCHERICHIA COLI; FECES; MICROBIOLOGY; PATHOGENICITY; PREVALENCE; SWINE; SWINE DISEASE;

ANIMAL HUSBANDRY; ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FECES; ONTARIO; PREVALENCE; SWINE; SWINE DISEASES;

EID: 0032571019     PISSN: 01675877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5877(97)00094-9     Document Type: Article

References (64)

1. Aalbaek, B., Rasmussen, J., Nielsen, B., Olsen, J.E., 1991. Prevalence of antibiotic-resistant Escherichia coli in Danish pigs and cattle. Acta Pathol. Microbiol. Immunol. Scand. 99, 1103-1110.
2. Agriculture Canada, 1990. Compendium of medicating ingredient brochures. Agriculture Canada, Ottawa.
3. Babcock, G.F., Berryhill, D.L., Marsh, D.H., 1973. R-factors of Escherichia coli from dressed beef and humans. Appl. Microbiol. 25 (1), 21-23.
4. Christie, P.J., Dunny, G.M., 1984. Antibiotic selection pressure resulting in multiple antibiotic resistance and localization of resistance to conjugative plasmids in streptococci. J. Infect. Dis. 149 (1), 74-82.
5. Coates, S.R., Hoopes, K.H., 1980. Sensitivities of Escherichia coli isolated from bovine and porcine enteric infections to antimicrobial substances. Am. J. Vet. Res. 41, 1882.
6. Corpet, D.E., 1993. An evaluation of methods to assess the effect of antimicrobial residues on the human gut flora. Vet. Microbiol. 35, 199-212.
7. Craven, J.A., Barnum, D.A., 1971. Ecology of intestinal Escherichia coli in pigs. Can. J. Comp. Med. 35, 325-331.
8. Das, N.K., 1984. In vitro susceptibility of Escherichia coli of swine origin to carbadox and other antimicrobials. Am. J. Vet. Res. 45 (2), 252-254.
9. Dawson, K.A., Langlois, B.E., Stahly, T.S., Cromwell, G.L., 1984. Antibiotic resistance in anaerobic and coliform bacteria from the intestinal tract of swine fed therapeutic and subtherapeutic concentrations of chlortetracycline. J. Anim. Sci. 58 (1), 123-131.
10. Devriese, L.A., 1975. Furizolidone sensitivity tests with Escherichia coli and Staphylococcus aureus strains of animal origin. Zbl. Vet. Med. 22, 220-229.
11. Dubel, J.R., Zink, D.L., Kelley, L.M., Naqi, S.A., Renshaw, H.W., 1982. Bacterial resistance: frequency of gentamicin-resistant strains of Escherichia coli in the fecal microflora of commercial turkeys. Am. J. Vet. Res. 43 (10), 1786-1789.
12. Dunlop, R.H., 1996. Antimicrobial treatments and antimicrobial resistance of fecal Escherichia coli of swine in Ontario, Canada. PhD Dissertation, University of Guelph, Guelph, Ontario, 1996, 351 pp.
13. Dunlop, R.H., McEwen, S.A., Meek, A.H., Black, W.D., Clarke, R.C., Friendship, R.M., 1998. Individual and group antimicrobial treatment rates on 34 farrow-to-finish swine farms in Ontario. Canada. Prev. Vet. Med. 34, 245-263.
14. Elbers, A.R.W., 1991. The use of slaughterhouse information in monitoring systems for herd health control in pigs. PhD Thesis, University of Utrecht, 152 pp.
15. Everitt, B.S., 1989. Measurement in medicine. In: Statistical Methods: for Medical Investigations. Oxford Univ. Press, New York, pp. 16-27.
16. Gast, R.K., Stephens, J.F., 1985. In vitro transfer of antibiotic resistance to a strain of Salmonella arizonae. Poult. Sci. 65, 270-279.
17. Hartl, D.L., Dykhuizen, D.E., 1984. The population genetics of Escherichia coli. Annu. Rev. Genet. 18, 31-68.
18. Helrich, K. (Ed.), 1990. Official Methods of Analysis of the Association of Official Analytical Chemists, 15th edn., Vol. 1. Association of Official Analytical Chemists, Arlington.
19. Hinton, M.M., Al-Chalaby, Z.A., Allen, V., Linton, A.H., 1982. The persistence of drug resistant Escherichia coli in the intestinal flora of healthy broiler chicks. J. Hyg. Camb. 89, 269-278.
20. Hinton, M., Hampson, D.J., Hampson, E., Linton, A.H., 1985a. A comparison of the ecology of Escherichia coli in the intestine of healthy unweaned pigs and pigs after weaning. J. Appl. Bacteriol. 58, 471-478.
21. Hinton, M., Hampson, D.J., Hampson, E., Linton, A.H., 1985b. The effects of oxytetracycline on the intestinal Escherichia coli flora of newly weaned pigs. J. Hyg. Camb. 95, 77-85.
22. Hinton, M., Lim, S.K., Linton, A.H., 1987. The influence of antibacterial agents on the complexity of the Escherichia coli flora of chickens. FEMS Microbiol. Lett. 41, 169-173.
23. Howe, K., Linton, A.H., 1976a. The distribution of O-antigen types of Escherichia coli in normal calves, compared with man, and their R plasmid carriage. J. Appl. Bacteriol. 40, 317-330.
24. Howe, K., Linton, A.H., Osborne, A.D., 1976b. An investigation of calf carcass contamination by Escherichia coli from the gut contents at slaughter. J. Appl. Bacteriol. 41, 37-45.
25. Hummel, R., Tschape, H., Witte, W., 1986. Spread of plasmid-mediated nourseothricin resistance due to antibiotic use in animal husbandry. J. Basic Microbiol. 26 (8), 461-466.
26. Hunter, J.E.B., Shelley, J.C., Walton, J.R., Hart, C.A., Bennett, M., 1992. Apramycin resistance plasmids in Escherichia coli: Possible transfer to Salmonella typhimurium in calves. Epidemiol. Infect. 108, 271-278.
27. Kanai, H., 1983. Drug-resistance and distribution of conjugative R plasmids in Escherichia coli strains isolated from healthy adult animals and humans. Jpn. J. Vet. Sci. 45, 171-178.
28. Kliebenstein, J.B., Kirtley, C.L., Selby, L.A., 1983. A survey of swine production health problems and health maintenance expenditures. Prev. Vet. Med. 1, 357-369.
29. Langlois, B.E., Cromwell, G.L., Stahly, T.S., Dawson, K.A., Hays, V.W., 1983. Antibiotic resistance of fecal coliforms after long-term withdrawal of therapeutic and subtherapeutic antibiotic use in a swine herd. Appl. Environ. Microbiol. 46 (6), 1433-1434.
30. Langlois, B.E., Dawson, K.A., Leak, I., Aaron, D.K., 1988. Antimicrobial resistance of fecal coliforms from pigs in a herd not exposed to antimicrobial agents for 126 months. Vet. Microbiol. 18, 147-153.
31. Larsen, J.L., Larsen, H.E., 1974. Udbredelse og persistens af antibiotikaresistente Escherichia coli i svinebesaetninger med intermitterende brug af antibiotika. [Distribution and persistence of drug resistant E. coli in swine herds with intermittent use of antibiotics] Nord. Med. 26, 417-429.
32. Linton, A.H., 1980. The role of meat in the spread to man of pathogenic and antibiotic-resistant bacteria. Meat Hygienist, February/March, pp. 22-27.
33. Linton, A.H., Howe, K., Osborne, A.D., 1975. The effects of feeding tetracycline, nitrovin and quindoxin on the drug resistance of coli-aerogenes bacteria from calves and pigs. J. Appl. Bacteriol. 38, 255-275.
34. Linton, A.H., Handley, B., Osborne, A.D., Shaw, B.G., Roberts, T.A., Hudson, W.R., 1976. Contamination of pig carcasses at two abattoirs by Escherichia coli with special reference to O-serotypes and antibiotic resistance. J. Appl. Bacteriol. 41, 89-110.
35. Linton, A.H., Howe, K., Bennett, P.M., Richmond, M.H., Whiteside, E.J., 1977a. The colonization of the human gut by antibiotic resistant Escherichia coli from chickens. J. Appl. Bacteriol. 43, 465-469.
36. Linton, A.H., Howe, K., Hartley, C.L., Clements, H.M., Richmond, M.H., 1977b. Antibiotic resistance among Escherichia coli O-serotypes from the gut and carcasses of commercially slaughtered broiler chickens: a potential public health hazard. J. Appl. Bacteriol. 42, 365-378.
37. Linton, A.H., Timoney, J.F., Hinton, M., 1981. The ecology of chloramphenicol-resistance in Salmonella typhimurium and Escherichia coli in calves with endemic salmonella infection. J. Appl. Bacteriol. 50, 115-129.
38. Linton, A.H., Hedges, A.J., Bennett, P.M., 1988. Monitoring for the development of antimicrobial resistance during the use of olaquindox as a feed additive on commercial pig farms. J. Appl. Bacteriol. 64, 311-327.
39. Liven, E., 1979. Drug resistance in strains of Escherichia coli isolated from the intestinal tract of pigs in Norway. ACTA Agric. Scand. 20, 258-269.
40. Martin, S.W., Meek, A.H., Willeberg, P., 1987. Veterinary epidemiology: principles and methods. Iowa State Univ. Press, Ames.
41. Molitoris, E., Fagerberg, D.J., Quarles, C.L., Krichevsky, M.I., 1987. Changes in antimicrobial resistance in fecal bacteria associated with pig transit and holding times at slaughter plants. Appl. Environ. Microbiol. 53, 1307-1310.
42. National Academy of Sciences, 1969. The use of drugs in animal feeds. Publication No. 1679, Natl. Acad. Sci., Washington, DC.
43. National Committee for Clinical Laboratory Standards, 1990. Approved standard M7-A2. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 2nd edn. National Committee for Clinical Laboratory Standards, Villanova, PA.
44. Neu, H.C., Cherubin, C.E., Longo, E.D., Flouton, B., Winter, J., 1975. Antimicrobial resistance and R-factor transfer among isolates of Salmonella in the northeastern United States: A comparison of human and animal isolates. J. Infect. Dis. 132 (6), 617-622.
45. Ohmae, K., Yonezawa, S., Terakado, N., 1981. Plasmid with carbadox resistance from Escherichia coli of porcine origin. Antimicrob. Agents Chemother. 19 (1), 86-90.
46. Ohmae, K., Yonezawa, S., Terakado, N., 1983. Epizootiological studies on R plasmid with carbadox resistance. Jpn. J. Vet. Sci. 45 (2), 165-170.
47. Ohmae, K., Hamamoto, S., Yonezawa, S., 1985. Naturally occurring plasmid coding for heat-labile enterotoxin production and drug resistance from Escherichia coli strain of porcine origin. Jpn. J. Vet. Sci. 47, 125-128.
48. Ozanne, G., Bedard, P., Ducic, S., Panisset, J.C., 1987. Antibiotic multiresistance among coliforms isolated from the gut of swine and abattoir workers: evidence of transfer from animal to man. Can. J. Public Health 78, 340-344.
49. Phillips, I., King, A., Rowe, B., Eykyn, S., Gransden, W.R., Frost, J.A., Gross, R.J., 1988. Epidemic multiresistant Escherichia coli infection in West Lambeth Health District. Lancet, pp. 1038-1041.
50. Saida, K., Ike, Y., Mitsuhashi, S., 1981. Drug resistance and R plasmids of Escherichia coli strains isolated from pigs, slaughterers, and breeders of pigs in Japan. Antimicrob. Agents Chemother. 19, 1032-1036.
51. Sharpe, A.N., Peterkin, P.I., 1988. Membrane filter food microbiology. Res. Studies Press, Taunton, UK (distributed by Wiley).
52. Sharpe, A.N., Rayman, M.K., Burgener, D.M., Conley, D., Loit, A., Milling, M., 1983. Collaborative study of the MPN, Anderson-Baird-Parker direct plating, and hydrophobic grid membrane filter methods for the enumeration of Escherichia coli biotype I in foods. Can. J. Microbiol. 29, 1247-1252.
53. Siegel, D., Huber, W.G., Enloe, F., 1974. Continuous non-therapeutic use of antibacterial drugs in feed and drug resistance of Gram-negative enteric florae of food-producing animals. Antimicrob. Agents Chemother. 6 (6), 697-701.
54. Smith, H.W., 1980. Antibiotic-resistant Escherichia coli in market pigs in 1956-1979: the emergence of organisms with plasmid-borne trimethoprim resistance. J. Hyg. Camb. 84, 467-477.
55. Smith, H.W., Crabb, W.E., 1957. The effect of the continuous administration of diets containing low levels of tetracyclines on the incidence of drug-resistant Bacterium coli in the faeces of pigs and chickens: the sensitivity of the Bact. coli to other chemotherapeutic agents. Vet. Rec. 69, 24-30.
56. Snedecor, G.W., Cochran, W.G., 1989. Statistical Methods, 8th edn. Iowa State Univ. Press, Ames.
57. Sogaard, H., 1973. Incidence of drug resistance and transmissible R factors in strains of Escherichia coli isolated from faeces of healthy pigs. Acta Vet. Scand. 14, 381-391.
58. Spanoghe, P., Pohl, P., 1987. Comparison between the influence of carbadox and that of traditional antibiotics on the resistance of enterobacteria in pigs. Ann. Rech. Vet. 18, 249-254.
59. Szabo, R., Todd, E., MacKenzie, J., Parrington, L., Armstrong, A., 1990. Increased sensitivity of the rapid hydrophobic grid membrane filter enzyme-labeled antibody procedure for Escherichia coli O157 detection in foods and bovine feces. Appl. Environ. Microbiol. 56, 3546-3549.
60. Tielen, M.J.M., Scheepens, C.J.M., Hessing, M., 1988. The influence of temperature and air velocity upon the state of health in pigs. In: Ekesbo, I. (Ed.), Proceedings of the 6th International Congress on Animal Hygiene: Environment and Animal Health, Vol. 1. Swedish University of Agricultural Sciences, Skara, Sweden, pp. 334-339.
61. Van Houweling, C.D., Gainer, J.H., 1978. Public health concerns relative to the use of subtherapeutic levels of antibiotics in animal feeds. J. Anim. Sci. 46 (5), 1413-1424.
62. Walton, J.R., 1972. A dynamic study of drug resistance in populations of faecal Escherichia coli from pigs fed nitrovin and furizolidone continuously. Zbl. Vet. Med. B 19, 646-654.
63. Walton, J.R., Lewis, L.E., 1971. Contamination of fresh and cooked meals by anlibiolic-resistant coliform bacteria. Lancet, pp. 255-257.
64. Williams, H., Lovell, M.A., 1984. Antibiotic resistance in Escherichia coli causing generalized infections in chickens in the UK in 1982: the relationship between the results of in vitro and in vivo furazolidone sensitivity tests. J. Hyg. Camb. 93, 445-453.