Tolerance induction by intrathymic inoculation prevents chronic renal allograft rejection

Transplantation

Volumn 65, Issue 2, 1998, Pages 272-275

  Blom, Dennis ^a   Morrissey, Nicholas ^a   Mesonero, Clara ^a   Zuo, Xiao Jing ^b   Jordan, Stanley ^b   Fisher, Terry ^a   Bronsther, Oscar ^a   Orloff, Mark S ^a,c  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c Box Surgery ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BONE MARROW TRANSPLANTATION; CHIMERA; DATA ANALYSIS; DOSE RESPONSE; GENE AMPLIFICATION; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; INOCULATION; ISOGRAFT; KIDNEY ALLOGRAFT; MICROFLUOROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032570324     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199801270-00024     Document Type: Article

References (11)

1. Adams DH, Tilney NL, Collins JJ, Karnovsky MJ. Experimental graft arteriosclerosis. I. The Lewis-to-F-344 allograft model. Transplantation 1992; 53: 1115.
2. Orloff MS, et al. Alterations of the interleukin-4 pathway in production of tolerance by mixed hematopoietic chimerism Surgery 1995; 118: 212.
3. Microsurgery (in press).
4. Orloff MS, et al. Prevention of chronic rejection and graft arteriosclerosis by tolerance induction. Transplantation 1995; 59: 282.
5. Cook DJ, Terasaki PI. Renal transplantation on the American continent. In: Brent L, Sells RA, eds. Organ transplantation: current clinical and immunological concepts. London: Balliere Tindall, 1989: 195.
6. Shin YT, Adams DH, Wyner LR, Enver A, Sayegh MH, Karnovsky M. Intrathymic tolerance in the Lewis-to-F-344 chronic cardiac allograft rejection model. Transplantation 1995; 59: 1647.
7. Fabre JW, Morris PJ. The effect of donor strain blood pretreatment on renal allograft rejection in rats. Transplantation 1972; 14: 608.
8. Josien R, Pannetier C, Douillard P, et al. Graft-infiltrating T helper cells, CD45RC phenotype, and Th1/Th2-related cytokines in donor-specific transfusion-induced tolerance in adult rats. Transplantation 1995; 60: 1131.
9. Dallman MJ, Osamu S, Page TH, Wood KJ, Morris PJ. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J Exp Med 1991; 173: 79.
10. Sayegh MH, Perico N, Gallon L, et al. Mechanisms of acquired thymic unresponsiveness to renal allografts. Transplantation 1994; 58: 125.
11. Blom D, Morrissey NJ, Mesonero C, et al. Induction of specific tolerance through mixed hematopoietic chimerism prevents chronic renal allograft rejection in a rat model. Surgery 1996; 120: 213.