Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190

Biochemistry

Volumn 37, Issue 4, 1998, Pages 971-982

  Lu, Fu ^a   Schumacher, Maria A ^c   Arvidson, Dennis N ^c   Haldimann, Andreas ^b   Wanner, Barry L ^b   Zalkin, Howard ^a   Brennan, Richard G ^c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; DNA BINDING; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; REGULON; REPRESSOR GENE; TRANSCRIPTION REGULATION;

ADENINE; ALANINE; ARGININE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; ENZYME REPRESSION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GLUTAMINE; GUANINE; HYPOXANTHINE; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PURINES; REPRESSOR PROTEINS;

EID: 0032570289     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971942s     Document Type: Article

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