A conserved TN8TCCT motif in the octapeptide-encoding region of Pax genes which has the potential to direct cytosine methylation

Gene

Volumn 223, Issue 1-2, 1998, Pages 303-308

  Ziman, M R ^a   Kay, P H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Codon usage; Conserved octapeptide; Conserved sequence; DNA methylation; Paired box homeobox genes

Indexed keywords

CYTOSINE; ESTROGEN RECEPTOR; HOMEODOMAIN PROTEIN; OCTAPEPTIDE; PROTEIN P53; DNA BINDING PROTEIN; MUSCLE PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; PAX7 PROTEIN, HUMAN; PAX8 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR PAX7;

BACTERIAL GENE; CONFERENCE PAPER; DEMETHYLATION; DNA METHYLATION; DNA SEQUENCE; GENETIC CONSERVATION; GENOME; HOMEOBOX; HUMAN T CELL LEUKEMIA VIRUS 1; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; RECEPTOR GENE; RETROVIRUS; TUMOR SUPPRESSOR GENE; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; GENETICS; HUMAN; METABOLISM; MULTIGENE FAMILY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; GENES, P53; HOMEODOMAIN PROTEINS; HUMANS; MULTIGENE FAMILY; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PAIRED BOX TRANSCRIPTION FACTORS; PAX7 TRANSCRIPTION FACTOR; RECEPTORS, ESTROGEN; TRANS-ACTIVATORS;

EID: 0032569732     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00162-0     Document Type: Conference Paper

References (26)

1. Adams B., Dörfler P., Aguzzi A., Kozmik Z., Urbánek P., Maurer-Fogy I., Busslinger M. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1992;1589-1607.
2. +-ATPase in nodules of Phaseoulus vulgaris L. Plant Mol. Biol. 32:1996;1043-1053.
3. Chalepakis G., Fritsch R., Fickenscher H., Deutsch U., Goulding M., Gruss P. The molecular basis of the undulated/Pax-1 mutation. Cell. 66:1991;873-884.
4. Dressler G.R., Deutsch U., Chowdhury K., Nornes H.O., Gruss P. Pax2 a new murine paired-box-containing gene and its expression in the developing excretory system. Development. 109:1990;787-795.
5. Faust P.L., Kornfeld S., Chirgwin J.M. Cloning and sequence analysis of cDNA for human cathepsin D. Proc. Natl. Acad. Sci. USA. 82:1985;4910-4914.
6. Green S., Walter P., Kumar V., Krust A., Bornert J-M., Argos P., Chambon P. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 320:1986;134-139.
7. Jost, J-P., Saluz, H.R., 1993. DNA Methylation: Molecular Biology and Biological Significance. Birkhauser, Basel.
8. Jostes B., Walther C., Gruss P. The murine paired box gene Pax7 is expressed specifically during the development of the nervous and muscular system. Mech. Dev. 33:1991;27-38.
9. Kageyama T., Tanabe K., Koiwai O. Structure and development of rabbit pepsinogens. J. Biol. Chem. 265:1990;17031-17038.
10. Kay P.H., Harmon D., Fletcher S., Ziman M., Jacobsen P.F., Papadimitriou J.M. Variation in the methylation profile and structure of Pax3 and Pax7 among different mouse strains and during expression. Gene. 184:1997;45-53.
11. Krauss S., Johansen T., Korzh V., Fjose A. Expression pattern of zebrafish pax genes suggests a role in early brain regionalization. Nature. 353:1991;267-270.
12. Lechner M.S., Dressler G.R. Mapping of Pax-2 transcription activation domains. J. Biol. Chem. 271:1996;21088-21093.
13. Magewa A.N., Jones P.A. Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer. Mol. Cell. Biol. 14:1994;4225-4232.
14. Martin P., Carriere C., Dozier C., Quatannens B., Mirabel M.A., Vandenbunder B., Stehelin D., Saule S. Characterization of a paired box- and homeobox-containing quail gene (Pax-QNR) expressed in the neuroretina. Oncogene. 7:1992;1721-1728.
15. Neubüser A., Koseki H., Balling R. Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. Dev. Biol. 170:1995;701-716.
16. Paine E., Garcia J., Philpott T.C., Shaw G., Ratner L. Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patients. Virology. 182:1991;111-123.
17. +-ATPase in Nicotiana plumbaginifolia. J. Biol. Chem. 267:1992;1204-1211.
18. Plachov D., Chowdhury K., Walther C., Simon D., Guenet J-L., Gruss P. Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development. 110:1990;643-651.
19. Poleev A., Fickenscher H., Mundlos S., Winterpacht A., Zabel B., Fidler A., Gruss P., Plachov D. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms, tumors. Development. 116:1992;611-623.
20. Schäfer B.W., Czerny T., Bernasconi M., Genini M., Busslinger M. Molecular cloning and characterization of a human PAX7 cDNA expressed in normal and neoplastic myocytes. Nucleic Acids Res. 22:1994;4574-4582.
21. Shapiro D.N., Sublett J.E., Li B., Downing J.R., Naeve C.W. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 53:1993;5108-5112.
22. Simons, A.F.M., De Vos, W.M., 1989. DNA fragments, containing a lactic acid bacterium-specific regulator region for the expression of genes coding for normally heterologous proteins. Patent: EP 0307011-A 5 15-MAR-1989; Nederlands Instituut Voor Zuivelonderzoek.
23. Stapleton P., Weith A., Urbánek P., Kozmik Z., Busslinger M. Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9. Nature Genet. 3:1993;292-299.
24. Szafranska B., Xie S., Green J., Roberts R.M. Porcine pregnancy-associated glycoproteins: new members of the aspartic proteinase gene family expressed in trophectoderm. Biol. Reprod. 53:1995;21-28.
25. Van Renterghem P., Vassart G., Christophe D. Pax8 expression in primary cultured dog thyrocyte is increased by cyclin AMP. Biochim. Biophys. Acta. Gene Struct. Express. 1307:1996;97-103.
26. Wada K., Wada Y., Ishibashi F., Gojobori T., Ikemura T. Codon usage tabulated from the GenBank genetic sequence data. Nucleic Acids Res. 20:1992;2111-2118.