Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect

Psychiatry Research - Neuroimaging

Volumn 83, Issue 2, 1998, Pages 105-115

  Heimberg, Carolyn ^a,b,f   Komoroski, Richard A ^b,c   Lawson, William B ^b,e   Cardwell, David ^b   Karson, Craig N ^b,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Brain imaging; Inositol; N acetylaspartate; NMR spectroscopy; Psychopharmacology; Psychosis

Indexed keywords

CHOLINE; CLOZAPINE; CREATINE; FLUPHENAZINE; FLUPHENAZINE DECANOATE; HALOPERIDOL; INOSITOL; MOLINDONE; N ACETYLASPARTIC ACID; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; TRIFLUOPERAZINE;

ADULT; AGED; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; MALE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PSYCHOPHARMACOLOGY; PSYCHOSIS; SCHIZOIDISM; SCHIZOPHRENIA;

ADULT; AGED; ANALYSIS OF VARIANCE; ANTIPSYCHOTIC AGENTS; ASPARTIC ACID; BASAL GANGLIA; BRAIN; CASE-CONTROL STUDIES; CHOLINE; CREATINE; FRONTAL LOBE; HUMANS; INOSITOL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; SCHIZOPHRENIA; TEMPORAL LOBE; THALAMUS;

EID: 0032569216     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4927(98)00034-1     Document Type: Article

References (32)

1. American Psychiatric Association, Committee on Nomenclature and Statistics. 1987. Diagnostic and Statistical Manual of Mental Disorders, 3rd ed., revised. American Psychiatric Association, Washington, DC.
2. Andreasen, N.C., Arndt, S., Swayze, V., Cizadlo, T., Flaum, M., O'Leary, D., Ehrhardt, J.C., Yuh, W.T.C., 1994. Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging. Science 266, 294-298.
3. Bertolino, A., Callicott, J.H., Elman, I., Mattay, V.S., Tedeschi, G., Frank, J.A., Breier, A., Weinberger, D.R., 1998. Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study. Biological Psychiatry 43, 641-648.
4. Brooks, W.M., Hodde-Vargas, J., Vargas, L.A., Yeo, R.A., Ford, C.C., Hendren, R.L., 1998. Frontal lobe of children with schizophrenia spectrum disorders: a proton magnetic resonance spectroscopic study. Biological Psychiatry 43, 263-269.
5. 1H-magnetic resonance spectroscopy of the left temporal and frontal lobes in schizophrenia: clinical, neurodevelopmental, and cognitive correlates. Biological Psychiatry 36, 792-800.
6. 1H magnetic resonance spectroscopy characterization of neuronal dysfunction in drug-naive, chronic schizophrenia. Academic Radiology 1, 211-216.
7. Choe, B-Y., Suh, T-S., Shinn, K-S., Lee, C-W., Lee, C., Paik, I-H., 1996. Observation of metabolic changes in chronic schizophrenia after neuroleptic treatment by in vivo hydrogen magnetic resonance spectroscopy. Investigative Radiology 31, 345-352.
8. Deicken, R.F., Zhou, L., Corwin, F., Vinogradov, S., Weiner, M.W., 1997. Decreased left frontal lobe N-acetylaspartate in schizophrenia. American Journal of Psychiatry 154, 688-690.
9. Deicken, R.F., Zhou, L., Schuff, N., Fein, G., Weiner, M.W., 1998. Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy. Biological Psychiatry 43, 483-488.
10. Essali, M.A., Das, I., de Belleroche, J., Hirsch, S.R., 1989. The platelet polyphosphoinositide system in schizophrenia: pathological and pharmacological implications. Schizophrenia Research 2, 148.
11. Essali, M.A., Das, I., de Belleroche, J., Hirsch, S.R., 1990. The platelet polyphosphoinositide system in schizophrenia: the effects of neuroleptic treatment. Biological Psychiatry 28, 475-487.
12. Fujimoto, T., Nakano, T., Takano, T., Takeuchi, K., Yamada, K., Fukuzako, T., Akimoto, H., 1996. Proton magnetic resonance spectroscopy of basal ganglia in chronic schizophrenia. Biological Psychiatry 40, 14-18.
13. Fukuzako, H., Takeuchi, K., Hokazono, Y., Fukuzako, T., Yamada, K., Hashiguchi, T., Obo, Y., Ueyama, K., Takigawa, M., Fujimoto, T., 1995. Proton magnetic resonance spectroscopy of the left medial temporal and frontal lobes in chronic schizophrenia: preliminary report. Psychiatry Research: Neuroimaging 61, 193-200.
14. Gadian, D.G., 1995. NMR and Its Applications to Living Systems, 2nd ed. Oxford University Press, Oxford.
15. Kaiya, H., Nishida, A., Imai, A., Nakashima, S., Nozawa, Y., 1989. Accumulation of diacylglycerol in platelet phosphoinositide turnover in schizophrenia: a biological marker of good prognosis? Biological Psychiatry 26, 669-676.
16. 31P NMR of cat optic nerve. Spectroscopy Letters 24, 1123-1144.
17. Kreis, R., Ernst, T., Ross, B.D., 1993. Absolute quantitation of water and metabolites in the human brain. II. Metabolite concentrations. Journal of Magnetic Resonance, Series B 102, 9-19.
18. 1H MRS of brain. Magnetic Resonance Imaging 14, 281-292.
19. Maier, M., Ron, M.A., Barker, G.J., Tofts, P.S., 1995. Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia. Psychological Medicine 25, 1201-1209.
20. Moats, R.A., Ernst, T., Shonk, T.K., Ross, B.D., 1994. Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magnetic Resonance in Medicine 32, 110-115.
21. 1H MRS) of the hippocampal formation in schizophrenia: a pilot study. British Journal of Psychiatry 165, 481-485.
22. 1H-magnetic resonance spectroscopy of postmortem brains with schizophrenia. Biological Psychiatry 42, 359-366.
23. Renshaw, P.F., Yurgelun-Todd, D.A, Tohen, M., Gruber, S., Cohen, B.M., 1995. Temporal lobe proton magnetic resonance spectroscopy of patients with first-episode psychosis. American Journal of Psychiatry 152, 444-446.
24. Salibi, N., Brown, M.A., 1998. Clinical MR Spectroscopy. Wiley-Liss, New York, pp. 134-137.
25. Sigmundsson, T., Simmons, A., Maier, M., Toone, B.K., Williams, S.C.R., Andrews, C., Glover, A., Ron, M.A, 1997. Single voxel in vivo proton magnetic resonance spectroscopy in the frontal lobe of schizophrenic patients with negative symptoms. Proceedings of the International Society of Magnetic Resonance in Medicine, 5th Scientific Meeting, Vancouver, BC, Canada, 1997, p. 1165.
26. Stanley, J.A, Williamson, P.C., Drost, D.J., Carr, T., Rylett, J., Merskey, H., 1992. In vivo proton magnetic resonance spectroscopy in never treated schizophrenics. Proceedings of the 145th Annual Meeting of the American Psychiatric Association, New Research Program and Abstracts, 1992. APA, Washington, DC, 50 (Abstract NR10).
27. Stanley, J.A, Williamson, P.C., Drost, D.J., Rylett, R.J., Carr, T.J., Malla, A., Thompson, R.T., 1996. An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients. Schizophrenia Bulletin 22, 597-609.
28. Strauss, W.L., Tsuruda, J.S., Richards, T.L., 1995. Partial volume effects in volume-localized phased-array proton spectroscopy of the temporal lobe. Journal of Magnetic Resonance Imaging 4, 433-436.
29. Webb, P.G., Sailasuta, N., Kohler, S.J., Raidy, T., Moats, R.A., Hurd, R.E., 1994. Automated single-voxel proton MRS: technical development and multisite verification. Magnetic Resonance in Medicine 31, 365-373.
30. 1H MRS study of never-treated schizophrenics and normals (Abstract 468.2). Society for Neuroscience Abstracts 22, 1190.
31. 1H spectroscopy of the temporal lobes in schizophrenic and bipolar patients. Society of Magnetic Resonance in Medicine Abstracts 2, 1539.
32. Zilbermann-Kaufman, M., Agam, G., Moscowits, L., Livne, A.A., Belmaker, R.H., 1992. Raised monophosphatase activity in schizophrenic patients. Clinica Chimica Acta 209, 89-93.