Mutations in the hydrophobic surface of an amphiphatic groove of 14-3- 3ζ disrupt its interaction with Raf-1 kinase

Journal of Biological Chemistry

Volumn 273, Issue 26, 1998, Pages 16297-16304

  Wang, H ^a   Zhang, L ^a   Liddington, R ^a   Fu, H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; LIGAND; MUTANT PROTEIN; PROTEIN 14 3 3; PROTEIN KINASE; RAF PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; HYDROPHOBICITY; LEUKEMIA CELL LINE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

14-3-3 PROTEINS; AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENZYME INHIBITORS; HUMANS; JURKAT CELLS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; ONCOGENE PROTEIN V-CBL; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN-TYROSINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCR; PROTO-ONCOGENE PROTEINS C-RAF; RETROVIRIDAE PROTEINS, ONCOGENIC; TYROSINE 3-MONOOXYGENASE;

EID: 0032568944     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.26.16297     Document Type: Article

References (48)