Consecutive and domino processes for the synthesis of a heavily functionalised tricyclic system

Tetrahedron Letters

Volumn 39, Issue 9, 1998, Pages 1041-1044

  Marotta, Emanuela ^a   Righi, Paolo ^a   Rosini, Goffredo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TRICYCLIC AROMATIC COMPOUND;

ANALYTIC METHOD; ARTICLE; BIOTRANSFORMATION; CATALYST; COMPLEX FORMATION; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROXYLATION; NONHUMAN; REACTION ANALYSIS;

EID: 0032568063     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10698-0     Document Type: Article

References (15)

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8. 7. Rosini, G. The Henry (Nitroaldol) Reaction. In Comprehensive Organic Synthesis; Trost, B. M.; Heathcock, C. H., Eds; Pergamon Press: Oxford, 1991; Vol.2, p 321 and references therein cited.
9. 8. Rosini, G.; Marotta, E.; Righi, P.; Seerden J.-P. J. Org. Chem. 1991, 56, 6258-6259; Rosini, G.; Galarini, R.; Marotta, E.; Righi, P. ibid. 1990, 55, 781-783.
10. 8. Rosini, G.; Marotta, E.; Righi, P.; Seerden J.-P. J. Org. Chem. 1991, 56, 6258-6259; Rosini, G.; Galarini, R.; Marotta, E.; Righi, P. ibid. 1990, 55, 781-783.
11. 9. For the use of the temporary silicon connection in organic synthesis see: Stork, G.; Kim, G. J. Am. Chem. Soc. 1992, 114, 1087-1088. For a review see: Bols, M.; Skydstrup, T. Chem. Rev. 1995, 95, 1253-1277.
12. 9. For the use of the temporary silicon connection in organic synthesis see: Stork, G.; Kim, G. J. Am. Chem. Soc. 1992, 114, 1087-1088. For a review see: Bols, M.; Skydstrup, T. Chem. Rev. 1995, 95, 1253-1277.
13. 10. Under the same conditions, aldehydes bearing a acetoxy-, benzoyloxy-, chloroacetoxy-, trichloroacetoxy, or a trifluoroacetoxy group on the α-carbon did not give ring closure, while α-mesyloxyaldehydes gave similar results to α-tosyloxyaldehydes in both yields and diastereoisomeric ratios of the products.
14. 11. This value was calculated following: Bertz, S. H.; Sommer, T. J. Applications of Graph Theory to Synthesis Planning: Complexity, Reflexivity, and Vulnerability. In Organic Synthesis: Theory and Applications; Hudlicky, T. Ed.; JAI Press Inc.: Greenwich, CT, 1993, Vol. 2, p. 67-92.
15. 3 solvent. Chemical shifts are reported in ppm downfield from tetramethylsilane (TMS) and coupling constants are expressed in hertz