2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline (NBQX) increases fibroblast growth factor mRNA levels after contusive spinal cord injury

Brain Research

Volumn 782, Issue 1-2, 1998, Pages 306-309

  Follesa, Paolo ^a   Wrathall, Jean R ^a   Mocchetti, Italo ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fibroblast growth factor; NBQX; Spinal cord injury

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; FIBROBLAST GROWTH FACTOR; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; WHITE MATTER;

ANIMALS; CONTUSIONS; EXCITATORY AMINO ACID ANTAGONISTS; FIBROBLAST GROWTH FACTORS; LAMINECTOMY; QUINOXALINES; RATS; RNA, MESSENGER; SPINAL CORD INJURIES; TISSUE DISTRIBUTION;

EID: 0032567725     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01296-1     Document Type: Article

References (17)

1. E.J. Collarini, W.D. Richardson, Growth factor for myelinating glial cells in the central and peripheral nervous system, In: S.E. Loughlin, J.H. Fallon (Eds.), Neurotrophic Factors. Academic Press, San Diego, CA, 1993.
2. Faden A.I., Ellison J.A., Noble L.J. Effects of competitive and non-competitive NMDA receptor antagonists in spinal cord injury. Eur. J. Pharmacol. 175:1990;165-174.
3. Follesa P., Mocchetti I. Regulation of basic fibroblast growth factor and nerve growth factor mRNA by β-adrenergic receptor activation and adrenal steroids in rat CNS. Mol. Pharmacol. 43:1993;132-138.
4. Follesa P., Wrathall J.R., Mocchetti I. Induction of bFGF mRNA in spinal cord trauma. Mol. Brain Res. 22:1994;1-8.
5. Gallo V., Russell J.T. Excitatory amino acid receptor in glia: different subtypes for distinct functions? J. Neurosci. Res. 42:1995;1-8.
6. Gomez-Pinilla F., Tram H., Cotman C.W., Nieto-Sampedro M. Neuroprotective effect of MK-801 and U-50488H after contusive spinal cord injury. Exp. Neurol. 104:1989;118-124.
7. Lindholm D., Castren E., Berzaghi M., Blochi A., Thoenen H. Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain-implication for neuronal plasticity. J. Neurobiol. 25:1994;1362-1372.
8. Liu D., Thangnipon W., McAdoo N. Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res. 547:1991;344-348.
9. Lyons M.K., Anderson R.E., Meyer F.B. Basic fibroblast growth factor promotes in vivo cerebral angiogenesis in chronic forebrain ischemia. Brain Res. 558:1991;315-320.
10. Mocchetti I., Colangelo A.M., Rabin S., Whittemore S.R., Wrathall J.R. Increased basic fibroblast growth factor expression following contusive spinal cord injury. Exp. Neurol. 141:1996;154-164.
11. Mocchetti I., Wrathall J.R. Neurotrophic factors in central nervous system trauma. J. Neurotrauma. 12:1995;853-870.
12. L.J. Rosenberg, Y.D. Teng, J.R. Wrathall, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline (NBQX) ameliorates acute axonal pathology after spinal cord injury. Soc. Neurosci. Abst. (1997) p. 541.3.
13. Schweigerer L., Neufeld G., Friedman J., Abraham J.A., Fiddes J., Gospodarowicz D. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature. 325:1987;257-259.
14. Wrathall J.R., Pettegrew R.K., Harvey F. Spinal cord contusion in the rat: production of graded, reproducible, injury groups. Exp. Neurol. 88:1985;108-122.
15. Wrathall J.R., Bouzoukis J., Choiniere D. Effect of kynurenate on functional deficit from traumatic spinal cord injury. Eur. J. Pharmacol. 218:1992;273-281.
16. Wrathall J.R., Choiniere D., Teng Y.D. Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX. J. Neurosci. 14:1994;6598-6607.
17. Young W. Secondary injury mechanisms in acute spinal cord injury. J. Emerg. Med. 11:1993;13-22.