ADP, adrenaline and serotonin stimulate inositol 1,4,5-trisphosphate production in human platelets

European Journal of Pharmacology

Volumn 358, Issue 1, 1998, Pages 93-100

  Vanags, Daina M ^a   Lloyd, John V ^b   Rodgers, Susan E ^b   Bochner, Felix ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

5 HT (5 hydroxytrytamine, serotonin); ADP; Adrenaline; Ca2+; Human platelet; Inositol 1,4,5 trisphosphate; Synergism

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ADRENALIN; CALCIUM; INOSITOL 1,4,5 TRISPHOSPHATE; SEROTONIN;

ARTICLE; CALCIUM CELL LEVEL; HUMAN; HUMAN CELL; HYDROLYSIS; NORMAL HUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; ASPIRIN; BLOOD PLATELETS; CALCIUM; DRUG SYNERGISM; EPINEPHRINE; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; SEROTONIN;

EID: 0032566776     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00595-0     Document Type: Article

References (35)

1. Agranoff B.W., Murthy P., Seguin E.B. Thrombin - induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets. J. Biol. Chem. 258:1983;2076-2078.
2. Blockmans D., Deckmyn H., Vermylen J. Platelet activation. Blood Rev. 9:1995;143-156.
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
4. Bredt D.S., Mourey R.J., Snyder S.H. A simple, sensitive and specific radioreceptor assay for inositol 1,4,5-trisphosphate in biological tissues. Biochem. Biophys. Res. Commun. 159:1989;976-982.
5. Challiss R.A.J., Batty I.H., Nahorski S.R. Mass measurements of inositol 1,4,5-trisphosphate in rat cerebellar cortex slices using a radioreceptor assay. Biochem. Biophys. Res. Commun. 157:1988;684-691.
6. Cotecchia S., Kobilka B.K., Daniel K.W., Nolan R.D., Lapetina E.Y., Caron M.G., Lefkowitz R.J., Regan J.W. Multiple second messenger pathways of α-adrenergic receptor subtypes expressed in eukaryotic cells. J. Biol. Chem. 265:1990;63-69.
7. 3 formation in human platelets. FEBS Lett. 206:1986;299-303.
8. Daniel J.L., Dangelmaier C.A., Smith J.B. Formation and metabolism of inositol 1,4,5-trisphosphate in human platelets. Biochem. J. 246:1987;109-114.
9. De Chaffoy de Courcelles D., Leysen J.E., De Clerck F., Van Belle H., Janssen P.A.J. Evidence that phospholipid turnover is the signal transduction system coupled to 5-HT S2 receptor sites. J. Biol. Chem. 260:1985;7603-7608.
10. Deykin D., Snyder D. Effect of epinephrine on platelet lipid metabolism. J. Lab. Clin. Med. 82:1973;554-559.
11. Drummond, A.H., MacIntyre, D.E., 1987. Platelet inositol lipid metabolism and calcium flux. In: MacIntyre, D.E., Gordon, J.L. (Eds.), Platelets in Biology and Pathology III, Elsevier, Amsterdam, pp. 373-422.
12. Duncan E.M., Tunbridge L.J., Lloyd J.V. An increase in phosphatidic acid in the absence of changes in diacylglycerol in human platelets stimulated with ADP. Int. J. Biochem. 25:1992;23-27.
13. Fisher G.J., Bakshian S., Baldassare J.J. Activation of human platelets with ADP causes a rapid rise in cytosolic free calcium without hydrolysis of phosphatidylinositol 4,5-bisphosphate. Biochem. Biophys. Res. Commun. 129:1985;958-964.
14. d 7.9 μmol/L) platelet binding sites for ADP and competition by ADP analogues. Blood. 71:1988;110-116.
15. Kobilka B.K., Matsui H., Kobilka T.S., Yang-Feng T.L., Francke U., Caron M.G., Lefkowitz R.J., Regan J.W. Cloning, sequencing and expression of the gene coding for the human platelet α-2-adrenergic receptor. Science. 238:1987;650-656.
16. Kroegel C., Chilvers E.R., Giembycz M.A., Challiss R.A.J., Barnes P.J. Platelet-activating factor stimulates a rapid accumulation of inositol (1,4,5)trisphosphate in guinea pig eosinophilis: relationship to calcium mobilisation and degranulation. J. Allergy Clin. Immunol. 88:1991;114-124.
17. Lalau-Keraly C., Vickers J.D., Kinlough-Rathbone L., Mustard J.F. Involvement of phosphoinositide metabolism in potentiation by adrenaline of ADP-induced aggregation of rabbit platelets. Biochem. J. 242:1987;841-847.
18. 32P content of phosphatidic acid and the phosphoinositides of rabbit platelets during aggregation induced by collagen or thrombin Br. J. Haematol. 26:1974;243-253.
19. 32P labelling of platelet phospholipids in response to ADP Br. J. Haematol. 23:1972;571-585.
20. 32P incorporation into phosphatidic acid and mono-, di- and triphosphatidylinositol Br. J. Haematol. 24:1973;589-604.
21. 32P into phosphatidic acid and mono-, di- and triphosphatidylinositol Br. J. Haematol. 25:1973;77-99.
22. MacIntyre D.E., Pollock W.K., Shaw A.M., Bushfield M., McMillan L.J., McNicol A. Agonist induced inositol phospholipid metabolism and calcium flux in human platelet activation. Adv. Exp. Med. Biol. 192:1985;127-144.
23. Molner J., Lorand L. Preparation of apyrase. Arch. Biochem. Biophys. 93:1961;353-355.
24. Mustard J.F., Kinlough-Rathbone R., Packham M.A. Isolation of human platelets from plasma by centrifugation and washing. Methods Enzymol. 169:1989;3-11.
25. Potevin F., Lecompte T., Favier R., Samana M. Rapid aequorin loading into platelets in the presence of DMSO - characteristics of the responses (changes in light transmission and in calcium) to various agonists. Thromb. Haemost. 66:1990;334-342.
26. Raha S., Jones G.D., Gear A.R. Sub-second oscillations of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate during platelet activation by ADP and thrombin. Biochem. J. 292:1993;643-646.
27. Rittenhouse S.E., Sasson J.P. Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. J. Biol. Chem. 260:1985;8657-8660.
28. Sage S.O., Rink T.J. The kinetics of changes in intracellular calcium concentration in fura-2 loaded human platelets. J. Biol. Chem. 262:1987;16364-16369.
29. Schächter M., Godfrey P.P., Minchin M.C.W., McClue S.J., Young M.M. Serotonergic agonists stimulate inositol lipid metabolism in rabbit platelets. Life Sci. 37:1985;1641-1647.
30. Siess W., Weber P.C., Lapetina E.G. Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet activating factor. J. Biol. Chem. 259:1984;8286-8292.
31. Tysnes O.B., Steen V.M., Aarbakke G.M., Holmsen H. Stimulation of platelets with low concentrations of thrombin: evidence for equimolar accumulation of inositol trisphosphates and phosphatidic acid. Int. J. Biochem. 23:1991;305-310.
32. Vanags D.M., Rodgers S.E., Duncan E.M., Lloyd J.V., Bochner F. Potentiation of ADP-induced aggregation in human platelet-rich plasma by 5-hydroxytryptamine and adrenaline. Br. J. Pharmacol. 106:1992;917-923.
33. Vickers J.D., Kinlough-Rathbone R.L., Mustard J.F. Changes in phosphatidylinositol 4,5-bisphosphate 10 seconds after stimulation of washed rabbit platelets with ADP. Blood. 60:1982;1247-1250.
34. Vickers J.D., Kinlough-Rathbone R.L., Mustard J.F. The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation. Biochem. J. 237:1986;327-332.
35. Vickers J.D., Kinlough-Rathbone R.L., Packham M.A., Mustard J.F. Inositol phospholipid metabolism in human platelets stimulated by ADP. Eur. J. Biochem. 193:1990;521-528.