Group II intron mobility in yeast mitochondria: Target DNA-primed reverse transcription activity of all and reverse splicing into DNA transposition sites in vitro

Journal of Molecular Biology

Volumn 282, Issue 3, 1998, Pages 505-523

  Yang, Jian ^a,d   Mohr, Georg ^a,b   Perlman, Philip S ^c   Lambowitz, Alan M ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

DNA endonuclease; Recombination; Reverse transcriptase; Ribozyme; Transposition

Indexed keywords

COMPLEMENTARY DNA; DEOXYRIBONUCLEASE; ENDONUCLEASE; MITOCHONDRIAL DNA; RIBONUCLEOPROTEIN; RNA; RNA DIRECTED DNA POLYMERASE; TRANSCRIPTASE;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA RECOMBINATION; DNA SYNTHESIS; DNA TRANSPOSITION; ENZYME ACTIVITY; INTRON; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; REVERSE TRANSCRIPTION; RNA SPLICING; YEAST; YEAST CELL;

EID: 0032566493     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2029     Document Type: Article

References (20)

1. Bonitz, S. G., Coruzzi, G., Thalenfeld, B. E., Tzagoloff, A. & Macino, G. (1980). Assembly of the mitochondrial membrane system. Structure and nucleotide sequence of the gene coding for subunit 1 of yeast cytochrome oxidase. J. Biol. Chem. 255, 11927-11941.
2. Cote, F. & Perreault, J. P. (1997). Peach latent mosaic viroid is locked by a 2′,5′-phosphodiester bond produced by in vitro self-ligation. J. Mol. Biol. 273, 533-543.
3. Cousineau, B., Smith, D., Lawrence-Cavanagh, S., Mueller, J. E., Yang, J., Mills, D., Manias, D., Dunny, G., Lambowitz, A. M. & Belfort, M. (1998). Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination. Cell, in the press.
4. Eskes, R., Yang, J., Lambowitz, A. M. & Perlman, P. S. (1997). Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Cell, 88, 865-874.
5. Guo, H., Zimmerly, S., Perlman, P. S. & Lambowitz, A. M. (1997). Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA. EMBO J. 16, 6835-6848.
6. Kennell, J. C., Moran, J. V., Perlman, P. S., Butow, R. A. & Lambowitz, A. M. (1993). Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell, 73, 133-146.
7. Lazowska, J., Meunier, B. & Macadre, C. (1994). Homing of a group II intron in yeast mitochondrial DNA is accompanied by unidirectional co-conversion of upstream-located markers. EMBO J. 13, 4963-4972.
8. Lorsch, J. R., Bartel, D. P. & Szostak, J. W. (1995). Reverse transcriptase reads through a 2′-5′ linkage and a 2′-thiophosphate in a template. Nucl. Acids Res. 23, 2811-2814.
9. Matsuura, M., Saldanha, S., Ma, H., Wank, H., Yang, J., Mohr, G., Cavanagh, S., Dunny, G. M., Belfort, M. & Lambowitz, A. M. (1997). A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron. Genes Dev. 11, 2910-2924.
10. Michel, F. & Ferat, J.-L. (1995). Structure and activities of group II introns. Annu. Rev. Biochem. 64, 435-461.
11. Moran, J. V., Zimmerly, S., Eskes, R., Kennell, J. C., Lambowitz, A. M., Butow, R. A. & Perlman, P. S. (1995). Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelement. Mol. Cell. Biol. 15, 2828-2838.
12. Mueller, M. W., Allmaier, M., Eskes, R. & Schweyen, R. J. (1993). Transposition of group II intron all in yeast and invasion of mitochondrial genes at new locations. Nature, 366, 174-176.
13. Perlman, P. S. & Mahler, H. R. (1983). Genetics and biogenesis of cytochrome b. Methods Enzymol. 97, 374-395.
14. Sanger, F., Nicklen, S. & Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA, 74, 5463-5467.
15. Schmidt, W. M., Schweyen, R. J., Wolf, K. & Mueller, M. W. (1994). Transposable group II introns in fission and budding yeast: site-specific genomic instabilities and formation of group II IVS plDNAs. J. Mol. Biol. 243, 157-166.
16. Vogel, J., Hess, W. R. & Borner, T. (1997). Precise branch point mapping and quantification of splicing intermediates. Nucl. Acids Res. 25, 2030-2031.
17. Wenzlau, J. M., Saldanha, R. J., Butow, R. A. & Perlman, P. S. (1989). A latent intron-encoded maturase is also an endonuclease needed for intron mobility. Cell, 56, 421-430.
18. Yang, J., Zimmerly, S., Perlman, P. S. & Lambowitz, A. M. (1996). Efficient integration of an intron RNA into double-stranded DNA by reverse splicing. Nature, 381, 332-335.
19. Zimmerly, S., Guo, H., Perlman, P. S. & Lambowitz, A. M. (1995a). Group II intron mobility occurs by target DNA-primed reverse transcription. Cell, 82, 545-554.
20. Zimmerly, S., Guo, H., Eskes, R., Yang, J., Perlman, P. S. & Lambowitz, A. M. (1995b). A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell, 83, 529-538.