Rigid chiral carbocyclic clefts as building blocks for the construction of new supramolecular hosts

Tetrahedron Letters

Volumn 39, Issue 52, 1998, Pages 9809-9812

  Try, Andrew C ^a   Painter, Leoni ^a   Harding, Margaret M ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE;

ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; CYCLIZATION; MOLECULAR RECOGNITION; SYNTHESIS;

EID: 0032564537     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02179-0     Document Type: Article

References (24)

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19. 11. While unsymmetrical Tröger's Base systems may be prepared with a halogen (Cl) incorporated on one of the aryl rings), attempts to synthesise the dichloro substituted Tröger's base failed; see T. H. Webb and C. S. Wilcox, J. Org. Chem. 1990, 55, 363.
20. 2 requires: C, 82.6; H, 5.8.
21. 13. The enantiomers were resolved on a Pirkle Type 1A chiral column (3.0 mL/min, 1.5% isopropanol/light petroleum); (+)-3 (99.8% pure), retention time 22 min, (-)-3, (93.3% pure) retention time 23.5 min; (+)-4 (99.4% pure), retention time 20 min. (-)-4 (97.3% pure) retention time 22 min.
22. -3.
23. 15. For example T. N. Mitchell, Synthesis 1992, 803; J. K. Stille, Angew. Chem., Int. Ed. Engl. 1986, 25, 508.
24. 15. For example T. N. Mitchell, Synthesis 1992, 803; J. K. Stille, Angew. Chem., Int. Ed. Engl. 1986, 25, 508.