Altered peptide ligands act as partial agonists by inhibiting phospholipase C activity induced by myasthenogenic T cell epitopes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 24, 1998, Pages 14320-14325

  Faber Elmann, Anat ^a   Paas Rozner, Miri ^a   Sela, Michael ^a   Mozes, Edna ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Autoimmune myasthenia gravis; Peptide analogs; Signal transduction; T cell receptor; Tyrosine phosphorylation

Indexed keywords

CHOLINERGIC RECEPTOR; EPITOPE; INOSITOL PHOSPHATE; LIGAND; PHOSPHOLIPASE C; RECEPTOR SUBUNIT; SYNTHETIC PEPTIDE;

ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MYASTHENIA GRAVIS; NEUROMUSCULAR JUNCTION DISORDER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; EPITOPES; HUMANS; INOSITOL PHOSPHATES; ISOENZYMES; KINETICS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MYASTHENIA GRAVIS; PEPTIDE FRAGMENTS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; RECEPTORS, CHOLINERGIC; T-LYMPHOCYTES;

EID: 0032564415     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.24.14320     Document Type: Article

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