Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase

FEBS Letters

Volumn 437, Issue 3, 1998, Pages 273-277

  Fang, Rui ^a   Nixon, Peter F ^b   Duggleby, Ronald G ^b  

^a JILIN UNIVERSITY   (China)

^b Funct Eng   (Australia)

Author keywords

Active site; Catalytic mechanism; Enzyme activity; Pyruvate dehydrogenase; Site directed mutagenesis; Thiamine diphosphate

Indexed keywords

COCARBOXYLASE; GLUTAMIC ACID; PYRUVATE DEHYDROGENASE;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME MODIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; HUMAN; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; GLUTAMIC ACID; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PYRUVATE DEHYDROGENASE (LIPOAMIDE); PYRUVATE DEHYDROGENASE COMPLEX; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; THIAMINE PYROPHOSPHATE;

EID: 0032561512     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01249-6     Document Type: Article

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