First direct synthesis of pyrrolo[1,2-α]thieno[3,2-ε]- or [2,3- ε][1,4]diazepines, thiophene analogues of pyrrolo [2,1- c][1,4]benzodiazepines

Tetrahedron Letters

Volumn 39, Issue 30, 1998, Pages 5369-5372

  Jolivet Fouchet, Sandrine ^a   Fabis, Frédéric ^a   Rault, Sylvain ^a  

^a UNIVERSITÉ DE CAEN   (France)

Author keywords

Pyrrolo 1,2 thieno 3,2 or 2,3 1,4 diazepines; Pyrrolo 2,1 c 1,4 benzodiazepines; Thiaisatoic anhydrides

Indexed keywords

PYRROLO[1,2 A]THIENO[3,2 E]BENZODIAZEPINE DERIVATIVE; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE; PYRROLO[2,3 E][1,4]BENZODIAZEPINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0032560707     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01108-3     Document Type: Article

References (9)

1. [1] a. Bose DS, Thompson AS, Smellie M, Berardini MD, Hartley SA, Jenkins TC, Neidle S, Thurston DE. J. Chem. Soc., Chem. Commun. 1992: 1518-1520.
2. b. Jenkins TC, Hurley LH, Neidle S, Thurston DE. J. Med. Chem. 1994, 37: 4529-4537.
3. c. Thurston DE, Morris SJ, Hartley JA. J. Chem. Soc., Chem. Commun. 1996: 563-565.
4. [2] Thurston DE, Bose DS. Chem. Rev. 1994, 94: 433-467.
5. [3] O'Neil IA, Murray CL, Hunter RC, Kalindjian SB, Jenkins TC. Synlett. 1997: 75-78.
6. [4] Kamal A, Howard PW, Reddy BSN, Reddy BSP, Thurston DE. Tetrahedron. 1997, 53(9): 3223-3230.
7. [5] Walser A, Flynn T. J. Het. Chem. 1992, 29: 1477-1480 (and references cited therein).
8. [6] Fabis F, Jolivet-Fouchet S, Robba M, Landelle H, Rault S. Tetrahedron. 1998, 54 : 00-00 (in press).
9. 2S: C, 54.04; H, 4.53; N, 12.60. Found C, 53.72; H, 4.56; N, 12.36.