A synthesis of 4-thiomethylbenzisothiazolone-1,1-dioxide using HDPT

Tetrahedron Letters

Volumn 39, Issue 30, 1998, Pages 5309-5312

  Yeung, Kap Sun ^a   Meanwell, Nicholas A ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Benzisothiazolones; Biologically active compounds; Halogenations; Thiols

Indexed keywords

1 (2 HYDROXYETHYL) 4,6 DIPHENYLPYRIDINE 2 THIONE; 4 THIOMETHYLBENZISOTHIAZOLONE 1,1 DIOXIDE; BROMIDE; OXIDE; THIOL; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; DRUG SYNTHESIS; HALOGENATION;

EID: 0032560705     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01074-0     Document Type: Article

References (20)

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18. (15) HDPT was prepared according to the procedures described in Ref. 10.
19. 2 (343.4120) Calcd. C, 48.97; H, 4.99; N, 4.08. Found C, 49.24; H, 4.86; N, 4.08.
20. (17) No reaction was observed by TLC analysis when a mixture of 4 in MeCN was stirred at elevated temperature (50°C).