Effect of steroids on DNA synthesis in an in vitro replication system: Initial quantitative structure - Activity relationship studies and construction of a non-estrogen receptor pharmacophore

Journal of Medicinal Chemistry

Volumn 41, Issue 9, 1998, Pages 1392-1398

  Azzaoui, Kamal ^a,d   Diaz Perez, Maria J ^a,b   Zannis Hadjoupoulos, Maria ^c   Price, Gerry B ^c   Wainer, Irving W ^a,d  

^a Department of Oncology   (Canada)

^b Department of Pharmacology ^*  (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16 KETO BETA ESTRADIOL; 16,17 EPIESTRIOL; 16ALPHA HYDROXYESTRONE; 16BETA HYDROXYESTRONE; 17 EPIESTRIOL; 2 HYDROXYESTRADIOL; 2 HYDROXYESTRONE; 2,3 METHOXYESTRONE; 4 HYDROXYESTRADIOL; 4 METHOXYESTRONE; BETA ESTRADIOL 17 ACETATE; DRUG CARRIER; EPIESTRIOL; ESTRIOL; ESTROGEN RECEPTOR; ESTRONE; ESTRONE ACETATE; PROGESTERONE; STEROID HORMONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; DNA REPLICATION; DNA SYNTHESIS; HORMONAL CARCINOGENESIS; HORMONE METABOLISM; HUMAN; HUMAN CELL; MOLECULAR MODEL; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR BINDING; STEROID ANALYSIS;

DNA; DNA REPLICATION; HELA CELLS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, STEROID; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032560136     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970725m     Document Type: Article

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