The globular domain of histone H1 is sufficient to direct specific gene repression in early Xenopus embryos

Current Biology

Volumn 8, Issue 9, 1998, Pages 533-536

  Vermaak, Danielle ^a   Steinbach, Oliver C ^b   Dimitrov, Stephan ^a   Rupp, Ralph A W ^b   Wolffe, Alan P ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b FRIEDRICH MIESCHER LABORATORY OF THE MAX PLANCK SOCIETY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN STRUCTURE; TRANSCRIPTION REGULATION;

AMPHIBIA; METAZOA; REPTILIA; VERTEBRATA; XENOPUS;

EID: 0032559972     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(98)70206-4     Document Type: Article

References (19)

1. Bates DL, Thomas JO: Histones H1 and H5: one or two molecules per nucleosome. Nucleic Acids Res 1981, 9:5883-5894.
2. Hartman PG, Chapman GE, Moss T, Bradbury EM: Studies on the role and mode of operation of the very-lysine-rich histone H1 in eukaryotic chromatin: the three structural regions of the histone H1 molecule. Eur J Biochem 1977, 77:45-51.
3. Allan J, Hartman PG, Crane-Robinson C, Aviles FX: The structure of histone H1 and its location in chromatin. Nature 1980, 288:675-679.
4. Crane-Robinson C: Where is the globular domain of linker histone located on the nucleosome? Trends Biochem Sci 1997, 22:75-77.
5. Allan J, Mitchell T, Harborne N, Bohm L, Crane-Robinson C: Roles of H1 domains in determining higher-order chromatin structure and H1 location. J Mol Biol 1986, 187:591-601.
6. Bouvet P, Dimitrov S, Wolffe AP: Specific regulation of chromosomal 5S rRNA gene transcription in vivo by histone H1. Genes Dev 1994, 8:1147-1159.
7. Prymakowska-Boasak M, Przewloka MR, Iwkiewicz J, Egierszdorff S, Kuras M, Chaubet N, et al.: Histone H1 overexpressed to high level in tobacco affects certain developmental programs but has limited effect on basal cellular functions. Proc Natl Acad Sci USA 1996, 93:10250-10255.
8. Shen X, Gorovsky MA: Linker histone H1 regulates specific gene expression but not global transcription in vivo. Cell 1996, 86:475-483.
9. Kandolf H: The H1A histone variant is the in vivo repressor of oocyte-type 5S gene transcription in Xenopus laevis embryos. Proc Natl Acad Sci USA 1994; 91:7257-7260.
10. Dimitrov S, Almouzni G, Dasso M, Wolffe AP: Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. Dev Biol 1993, 160:214-227.
11. Steinbach OC, Wolffe AP, Rupp R: Somatic linker histones cause loss of mesodermal competence in Xenopus. Nature 1997, 389:395-399.
12. Breeuwer M, Goldfarb DS: Facilitated nuclear transport of histone H1 and other small nucleophilic proteins. Cell 1990, 60:999-1008.
13. Dingwall C, Allan J: Accumulation of the isolated carboxy-terminal domain of histone H1 in the Xenopus oocyte nucleus. EMBO J 1984, 3:1933-1943.
14. Freeman L, Kurumizaka H, Wolffe AP: Functional assays for assembly of histones H3 and H4 into the chromatin of Xenopus embryos. Proc Natl Acad Sci USA 1996, 93:12780-12785.
15. Ura K, Hayes JJ, Wolffe AP: A positive role for nucleosome mobility in the transcriptional activity of chromatin templates: restriction by linker histones. EMBO J 1995, 14:3752-3765.
16. Sera T, Wolffe AP: The role of histone H1 as an architectural determinant of chromatin. Mol Cell Biol 1998, in press.
17. Shim EY, Woodcock C, Zaret KS: Nucleosome positioning by the winged helix transcription factor HNF3. Genes Dev 1998, 12:5-10.
18. Pruss D, Bartholomew B, Persinger J, Hayes J, Arents G, Moudrianakis EN, Wolffe AP: An asymmetric model for the nucleosome: a binding site for linker histones inside the DNA gyres. Science 1996, 274:614-617.
19. Hayes JJ: Site-directed cleavage of DNA by a linker histone-Fe(ll) EDTA conjugate: localization of a globular domain binding site within a nucleosome. Biochemistry 1996, 35:11931-11937.