Role of cytoplasmic tail of the type 1A angiotensin II receptor in agonist- and phorbol ester-induced desensitization

Circulation Research

Volumn 82, Issue 5, 1998, Pages 523-531

  Tang, Hua ^a   Guo, Deng Fu ^a   Porter, James P ^b   Wanaka, Yoshio ^a   Inagami, Tadashi ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Angiotensin II; AT(1A) receptor; Desensitization; Phorbol ester

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; COMPLEMENTARY DNA; DIGITONIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; INOSITOL TRISPHOSPHATE; IODINE 125; LOSARTAN; MASTOPARAN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C INHIBITOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CHO CELL; DOSE TIME EFFECT RELATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0032559830     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.5.523     Document Type: Article

References (40)

1. Abdellatif MM, Neubauer FC, Lederer WJ, Rogers TB. Angiotensin- induced desensitization of the phosphoinositide pathway in cardiac cells occurs at the level of the receptor. Circ Res. 1991;69:800-809.
2. Tang H, Shirai H, Inagami T. Inhibition of protein kinase C prevents rapid desensitization of type 1B angiotensin II receptor. Circ Res. 1995;77:239-248.
3. Oppermann M, Freedman NJ, Alexander RW, Lefkowitz RJ. Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C. J Biol Chem. 1996;271:13266-13272.
4. Lefkowitz RJ, Hausdorff WP, Caron MG. Role of phosphorylation in desensitization of the β-adrenoceptor. Trends Pharmacol Sci. 1990;11:190-194.
5. 1A receptor in CHO-K1 cells. J Biol Chem. 1995;270:207-213.
6. 1A receptor. Eur J Pharmacol. 1995;291:135-141.
7. Du Y, Yao A, Guo D, Inagami T, Wang DH. Differential regulation of angiotensin II receptor subtypes in rat kidney by low dietary sodium. Hypertension. 1995;25(pt 2):872-877.
8. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chainterminating inhibitors. Proc Natl Acad Sci U S A. 1977;74:5463-5467.
9. 125I-LH-RH. Endocrinology. 1973;92:1725-1730.
10. Benya RV, Kusui T, Shikado F, Battey JF, Jensen RT. Desensitization of neuromedin B receptors (NMB-R) on native and NMB-R-transfected cells involves down-regulation and internalization. J Biol Chem. 1994;269:11721-11728.
11. Taylor ST, Chae HZ, Rhee SG, Exton JH. Activation of the β1 isozyme of phospholipase C by a subunits of the Gq class of G proteins. Nature. 1991;350:516-518.
12. 1 in vascular smooth muscle cells. J Biol Chem. 1994;269:10935-10939.
13. Brock TA, Rittenhouse SE, Powers CW, Ekstein LS, Gimbrone MA, Alexander RW. Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells. J Biol Chem. 1985;260:14158-14162.
14. Sakuta H, Sekiguchi M, Okamoto K, Sakai Y. Desensitization of endogenous angiotensin II receptors in Xenopus oocytes: a role of protein kinase C. Eur J Pharmacol. 1991;208:41-47.
15. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem. 1991;266:15771-15781.
16. 2+ accumulation in cardiac sarcoplasmic reticulum. J Biol Chem. 1990;265:4302-4308.
17. Higashijima T, Uzu S, Nakajima T, Ross EM. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J Biol Chem. 1988;263:6491-6494.
18. Haga K, Kameyama K, Haga T. Synergistic activation of a G protein- coupled receptor kinase by G protein βγ subunits and mastoparan or related peptides. J Biol Chem. 1994;269:12594-12599.
19. Benovic JL, Stone WC, Caron MG, Letkowitz RJ. Inhibition of the β-adrenergic receptor kinase by polyanions. J Biol Chem. 1989;264:6707-6710.
20. Loudon RP, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6. J Biol Chem. 1994;269:22691-22697.
21. Cheng HC, Litwin CM, Hwang DM, Wang JH. Structural basis of specific and efficient phosphorylation of peptides derived from p34cdc2 by a pp60src- related protein tyrosine kinase. J Biol Chem. 1991;266:17919-17925.
22. Lefkowitz RJ. G protein-coupled receptor kinases. Cell. 1993;74:409-412.
23. Keefer JR, Limbird LE. The alpha 2A-adrenergic receptor is targeted directly to the basolateral membrane domain of Madin-Darby canine kidney cells independent of coupling to pertussis toxin-sensitive GTP- binding proteins. J Biol Chem. 1993;268:11340-11347.
24. Haller H, Quass P, Lindschau C, Luft FC, Distler A. Platelet-derived growth factor and angiotensin II induce different spatial distribution of protein kinase C-α and -β in vascular smooth muscle cells. Hypertension. 1994;24:848-852.
25. Arai H, Escobedo JA. Angiotensin II type I receptor signals through raf-1 by a protein kinase C-dependent, ras-independent mechanism. Mol Pharmacol. 1996;50:522-528.
26. 1β-adrenergic receptor. J Biol Chem. 1994;269:22887-22893.
27. Tobin AB, Lambert DG, Nahorski SR. Rapid desensitization of muscarinic m3 receptor-stimulated polyphosphoinositide responses. Mol Pharmacol. 1992;42:1042-1048.
28. Sasaki K, Yamano Y, Bardhan S, Iwai N, Murray JJ, Hasegawa M, Matsuda Y, Inagami T. Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature. 1991;351:230-233.
29. Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature. 1991;351:233-236.
30. 2+ mobilization in renal mesangial cells. Eur J Pharmacol. 1993;245:15-21.
31. Pfeilschifter J, Fandrey J, Ochsner M, Whitebread S, De Gasparo M. Potentiation of angiotensin II-stimulated phosphoinositide hydrolysis, calcium mobilization and contraction of renal mesangial cells upon down- regulation of protein kinase C. FEBS Lett. 1990;261:307-311.
32. Pfeilschifter J, Ochsner M, Whitebread S, De Gasparo M. Down- regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells. Biochem J. 1989;262:285-291.
33. Brass LF. Homologous desensitization of HEL cell thrombin receptors. J Biol Chem. 1992;267:6044-6050.
34. Richardson RM, Haribabu B, Ali H, Snyderman R. Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. J Biol Chem. 1996;271:28717-28724.
35. Inglese J, Freedman NJ, Koch WJ, Lefkowitz RJ. Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem. 1993;268:23735-23738.
36. Palczewski K, Buczylko J, Lebioda L, Crabb JW, Polans AS. Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin. J Biol Chem. 1993;268:6004-6013.
37. Chen C-Y, Dion SB, Kim CM, Benovic JL. β-Adrenergic receptor kinase: agonist-dependent receptor binding promotes kinase activation. J Biol Chem. 1993;268:7825-7831.
38. Onorato JJ, Palczewski K, Regan J, Caron MG, Lefkowitz RJ, Benovic JL. Role of acidic amino acids in peptide substrates of the β-adrenergic receptor kinase and rhodopsin kinase. Biochemistry. 1991;30:5118-5125.
39. βγ subunits and lipid. J Biol Chem. 1995;270:11707-11710.
40. Tobin AB, Keys B, Nahorski SR. Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor. J Biol Chem. 1996;271:3907-3916.